AlphaGenome & the RNA world hypothesis | The chemical breakdown podcast

AlphaGenome & the RNA world hypothesis | The chemical breakdown podcast

Welcome to our latest podcast series, The chemical breakdown. Each week, we dive deeper into two stories we've covered here at Chemistry World, providing insight into the facts, why you should care, and what it means for the chemistry community. We also give you that week's headlines to keep you up to date with what's happening in the chemistry community. And finally, we'll end each episode with a brief section on what was happening this week in chemistry history.

This week, we discuss the new deep learning model AlphaGenome and visit the very beginning of life on Earth with Mason Wakley and Neil Withers.

Google DeepMind has released a new deep learning model that can predict the effect of small changes to DNA sequences up to one million base pairs in length. What does this new tech mean for our understanding of the human genome?

And, how did life start on Earth, before the first cell came to be? We discuss the RNA world hypothesis and breakdown the chemistry it's built on.

You can find more episodes of The chemical breakdown on the Chemistry world podcast feed. We would love to hear your feedback on this new podcast, so if you have any questions or comments please get in touch.

Jaksot(627)

Lopinavir: Chemistry in its element

Lopinavir: Chemistry in its element

Ben Valsler explains how a drug that prevents HIV from donning its protective 'coat' now makes up one arm of the World Health Organisation's Covid-19 trial

17 Huhti 20206min

Remdesivir: Chemistry in its element

Remdesivir: Chemistry in its element

Will new clinical trials for Covid-19 give remdesivir a second chance?Ben Valsler introduces the broad-spectrum antiviral that didn't quite make it as the Ebola drug it was originally planned to be.

3 Huhti 20206min

Chloroquine and hydroxychloroquine: Chemistry in its element

Chloroquine and hydroxychloroquine: Chemistry in its element

Old drugs sometimes find their way back into the news. The Covid-19 pandemic – and some very high profile backing – has led to malaria drugs chloroquine and hydroxychloroquine hitting the headlines wo...

27 Maalis 20207min

Ibuprofen: Chemistry in its element

Ibuprofen: Chemistry in its element

Brian Clegg on the popular over-the-counter painkiller, developed by a high-street pharmacy chain

20 Maalis 20209min

Minoxidil and finasteride: Chemistry in its element

Minoxidil and finasteride: Chemistry in its element

Catherine Hodges explores the chemical solutions to thinning hair and patchy beards, examining the popularity of minoxidil and the cautionary tale of finasteride

13 Maalis 20206min

Fipronil: Chemistry in its element

Fipronil: Chemistry in its element

The pesticide that keeps pets free of pests, but may have also been responsible for the devastating collapse of bee colonies. With Harriet Brewerton.

6 Maalis 20206min

Leptin: Chemistry in its element

Leptin: Chemistry in its element

Rotund rodents revolutionised our understanding of the biological role of fat. Now, as Katrina Krämer discovers, the hormones created by fats could redefine obesity.

28 Helmi 202010min

Vitamin K: Chemistry in its element

Vitamin K: Chemistry in its element

Ben Valsler on vitamin K – the blood clotting factor that is likely to be the first supplement you ever receive

21 Helmi 20206min

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