Marjolin's Ulcer: When a Chronic Wound Turns Cancerous

Marjolin's Ulcer: When a Chronic Wound Turns Cancerous

Dr. G explains Marjolin ulcer, a form of squamous cell carcinoma that can arise in long-standing, chronically inflamed or scarred wounds—especially diabetic foot ulcers—and why early recognition matters for limb salvage and survival.

Key signs include changing or hypertrophic margins, rolled or friable edges, unexplained bleeding, disproportionate pain, non-healing despite treatment, and nearby enlarged lymph nodes. Diagnosis requires a deep biopsy and imaging; treatment often involves wide surgical excision, possible lymph node assessment, and sometimes amputation or adjunct radiation.

Prevention and vigilance are crucial: optimize diabetes and vascular care, monitor chronic wounds closely, and refer promptly for suspicious changes. Emerging research on biomarkers, targeted therapies, and AI imaging aims to detect malignant transformation earlier.

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Jaksot(100)

Limb Watch: Every Wound Has A Clock

Limb Watch: Every Wound Has A Clock

In this episode Dr. G introduces Limb Watch, a simple framework to recognize early warning signs of diabetic foot disease before they become emergencies. She explains why small changes—warmth, redness...

8 Touko 10min

From Tuberculosis to Toes: Building a System That Stops Amputations

From Tuberculosis to Toes: Building a System That Stops Amputations

This episode compares tuberculosis control strategies to diabetic foot ulcer care, showing how a public-health system transformed TB from a deadly epidemic into a controllable disease and how similar ...

7 Touko 17min

The Magic Words in Woundcare- Words That Save Limbs: The Hidden Language of Diabetic Wound Care

The Magic Words in Woundcare- Words That Save Limbs: The Hidden Language of Diabetic Wound Care

This episode examines how medical language shapes urgency, triage, and outcomes in diabetic wound care. It explains key terms—like limb-threatening infection, critical limb ischemia, osteomyelitis, ne...

7 Touko 14min

THE GEOGRAPHY OF AMPUTATION”  Why Your Chances of Keeping a Leg Depend on Where You’re Born

THE GEOGRAPHY OF AMPUTATION” Why Your Chances of Keeping a Leg Depend on Where You’re Born

In this episode Dr. G explores how where a person lives can determine whether a diabetic foot ulcer heals or leads to amputation. Using real-world examples, he explains how limited access to podiatry,...

7 Touko 29min

H2 Therapy: Could Hydrogen Help Save Diabetic Feet?

H2 Therapy: Could Hydrogen Help Save Diabetic Feet?

In this episode Dr. G explores molecular hydrogen (H2) — the smallest molecule with surprising biological effects — and how its selective antioxidant and anti-inflammatory actions might improve wound ...

6 Touko 19min

Hidden in the Waves: Vibrio, Pseudomonas and the Dangers of Water to Diabetic Ulcers

Hidden in the Waves: Vibrio, Pseudomonas and the Dangers of Water to Diabetic Ulcers

This episode explains how common water sources — oceans, lakes, rivers, pools, hot tubs and aquariums — can introduce dangerous microbes into diabetic foot wounds, including Vibrio, Aeromonas, Pseudom...

26 Huhti 20min

Amputated Spirit: The Hidden Loss of Integrity in Diabetic Limb Care

Amputated Spirit: The Hidden Loss of Integrity in Diabetic Limb Care

Dr. G explores how diabetic limb salvage is not only about preventing physical amputation but also about protecting the clinician’s and patient’s integrity and will to fight. He warns that system dela...

25 Huhti 18min

Masked Threats: Microvascular Collapse, Gait Compensation, and Silent Biofilms

Masked Threats: Microvascular Collapse, Gait Compensation, and Silent Biofilms

Dr. G investigates a diabetic foot ulcer that appears routine but reveals multiple hidden causes: microvascular ischemia, compensatory gait mechanics, biofilm infection, immune suppression, static pre...

24 Huhti 10min

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