#202 Dementia Part 2: Gray Matters Segment

#202 Dementia Part 2: Gray Matters Segment

Most clinicians see dementia medications on the med rec, but many of us aren’t sure how much they actually help. In this episode we break down donepezil, memantine, and the new anti-amyloid drugs, and when to stop them.

• Do cholinesterase inhibitors really work?

• What should clinicians know about lecanemab and donanemab before referring patients?

• How much benefit should we expect and for how long?

• When should you deprescribe dementia medications?


🔹Sponsor: Caraway’s cookware set is a favorite for a reason.

For 10% off, go to Carawayhome.com/CoreIM or use code CoreIM at checkout.


🔹Transcript and Shownotes

02:27 | Deep Dive 1: How do we deliver the news of a diagnosis of dementia?

09:41 | Deep Dive 2: Prescribing medications for cognitive decline

29:30 | Deep Dive 3: Patient-centered management for a patient with cognitive decline

35:46 | Deep Dive 4: Planning for an uncertain future


Tags: CoreIM, Internal Medicine, Medical Education, Cognitive Screening, primary care, nurse practitioner, physician assistant



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Jaksot(212)

#28 What Would You Tell Your Younger Self?

#28 What Would You Tell Your Younger Self?

Women in medicine inspire us with what they would tell their younger selves. Some of the speakers with Shreya Trivedi MD @ShreyaTrivediMD at the Women in Medicine GirlMedLive Conference: Qaali Hussein...

21 Marras 201811min

#27 Treatment of Alcohol Use Disorder: 5 Pearls Segment

#27 Treatment of Alcohol Use Disorder: 5 Pearls Segment

Solidify your knowledge on Alcohol Use Disorder (AUD) treatment and more! Quiz yourself on the 5 pearls we will be covering: * Throwback: At what levels of drinking does unhealthy alcohol use start, ...

7 Marras 201827min

#26 A 85F with AMS Part 2: Hoofbeats Segment

#26 A 85F with AMS Part 2: Hoofbeats Segment

Dissect a working diagnosis through a process of validation! Time Stamps: * Your collective differential [0:40] * The test results (that you asked for) are in... [2:13] * The hospital course, and the...

24 Loka 201826min

#25 A 85F with AMS Part 1: Hoofbeats segment

#25 A 85F with AMS Part 1: Hoofbeats segment

Submit your diagnosis or differential for this episode's case at HumanDx.org (free registration required): http://hdx.org/2VP (http://hdx.org/2VP) ! Part 2 (releasing 10/24) will have the final diagno...

10 Loka 201833min

#24 Meet the Producers

#24 Meet the Producers

Join us in this episode with Doctors Who Create where we explore how Core IM was started and some things that happen behind the scenes! Episode page: https://www.coreimpodcast.com/2018/09/27/meet-the-...

27 Syys 201822min

#23 UTIs and Delirium: Mind the Gap Segment

#23 UTIs and Delirium: Mind the Gap Segment

Let's go deeper into the world of UTIs and delirium! The basics – what are the official (IDSA) definitions for bacteriuria, pyuria, and UTI? (02:07) The lay of the land – how common are bacteriu...

11 Syys 201819min

#22 Proton-Pump Inhibitors: 5 Pearls segment

#22 Proton-Pump Inhibitors: 5 Pearls segment

Solidify your knowledge on Proton-Pump Inhibitors (PPIs) and more! Quiz yourself on the 5 pearls we will be covering: * What are associated adverse effects for patients are on long-term PPIs? (2:02) ...

29 Elo 201827min

#21 57F with confusion: Hoofbeats segment

#21 57F with confusion: Hoofbeats segment

Dissect an interesting case and think about the way clinicians think! Many clinical reasoning pearls here: * Case history and exam 00:40 * Causal models 11:24 * Facets versus diagnoses 13:25 * Proble...

15 Elo 201835min

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