TWiP 199: Chagas kisses Cruzi and Brucei bites

TWiP 199: Chagas kisses Cruzi and Brucei bites

The TWiP team solves the case of the Traveler to Tanzania with a Purple Lesion, and discuss Mosquirix, the first vaccine approved for Plasmodium parasites.

Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula

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Case Study for TWiP 199

Gentleman in 40s, repeated intestinal issues, diagnosed with Giardia and treated, a year later again, again not feeling well. Stool testing shows Blastocystis and Endolimax nana. Lives in NYC area, single, active socially with different partners, no other medical problems, does take PREP for AIDS. Exam and labs normal except for stools. HIV negative. Treated with metronidazole, no impact on symptoms. Coincides with successful encounters.

Send your case diagnosis, questions and comments to twip@microbe.tv

Music by Ronald Jenkees

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Jaksot(285)

TWiP 285: Why Is Cyclospora So Hard to Contain? Parasitologists Explain the 2026 US Outbreak

TWiP 285: Why Is Cyclospora So Hard to Contain? Parasitologists Explain the 2026 US Outbreak

TWiP reviews our current understanding of the biology of Cyclospora, the parasite currently causing a large multistate outbreak in the US traced to contaminated lettuce, and why it is so difficult to ...

6 Elo 52min

TWiP 284: It's not the pork

TWiP 284: It's not the pork

TWiP solves the case of the 39-year-old man originally from Guatemala, who moved to one of the NYC boroughs in 2023 and presented with headaches for nearly 1 year. Hosts: Vincent Racaniello, Daniel Gr...

27 Heinä 50min

TWiP 283: Warming up to cryptosporidiosis

TWiP 283: Warming up to cryptosporidiosis

TWiP reviews the projected impact of climate change on the burden of Cryptosporidium in Mali, Kenya, and The Gambia. Hosts: Vincent Racaniello and Christina Naula Subscribe (free): Apple Podcasts, Goo...

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TWiP 282: Does he live in New York?

TWiP 282: Does he live in New York?

TWiP solves the case of the nonbinary patient in his 30s with a history HIV/AIDS presenting with 3 weeks of subjective fevers, chills, generalized weakness and voluminous ostomy output. Hosts: Vincent...

24 Kesä 53min

TWiP 281: Ants under the influence

TWiP 281: Ants under the influence

TWiP reviews gene expression in wood ants infected with the larval lancet fluke, which causes them to leave their nest and attach to a flower until they are eaten by a grazing mammal. Hosts: Vincent R...

22 Kesä 58min

TWiP 280: The wriggling diagnosis

TWiP 280: The wriggling diagnosis

TWiP solves the case of the 3 yo child, who recently immigrated to the US from Central America, in the ER with acute right lower quadrant abdominal pain and a rather active serpiginous wormlike 'thing...

29 Touko 57min

TWiP 279: Tolling for hookworms

TWiP 279: Tolling for hookworms

TWiP reviews a phase 2 clinical trial of a recombinant vaccine against N. americanus glutathione S-transferase-1, an enzyme that performs a crucial enzymatic step in hookworm blood feeding. Hosts: Vin...

1 Touko 50min

TWiP 278: Trichinella from eating bear eyeballs

TWiP 278: Trichinella from eating bear eyeballs

TWiP solves the case of the male in his 20s from Hokkaido, Japan, who developed fatigue and rash, followed by fever and myalgia 6 days later, after eating a raw bear eyeball. Hosts: Vincent Racaniello...

24 Huhti 56min

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