Plain English with Derek Thompson5 Touko

One of the Deadliest Cancers in America May Have Met Its Match

Hard to detect and almost impossible to treat, pancreatic cancer has long been one of medicine’s most ruthless killers. For decades, it’s been the cancer that science couldn’t crack. But that might be starting to change. Recently, cancer researchers have announced a series of breakthroughs that, taken together, sound almost too good to be true: a drug that targets the “undruggable” gene behind most pancreatic tumors, a personalized mRNA vaccine that teaches the immune system to recognize pancreatic cancer as an enemy, and, now, an AI program that can spot the elusive disease years before doctors typically find it. So is this breakthrough a real turning point? Or another case of medical hype outrunning reality? On today’s episode, Dr. Ajit Goenka of the Mayo Clinic joins Derek to walk through the science behind the latest advances in cancer detection and what they could mean for the future of health care. They discuss Dr. Goenka’s new research using artificial intelligence to detect pancreatic cancer earlier than ever before … and whether machines might soon see what doctors can’t. Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guest: Dr. Ajit Goenka Producer: Devon Baroldi Additional Production Support: Ben Glicksman Learn more about your ad choices. Visit podcastchoices.com/adchoices

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Why the NBA Feels Broken—and Why the League Can’t Fix It

The NBA’s vibes have been unusually awful recently. There has been widespread hand-wringing about the homogenization of modern offenses and the league’s notoriously weak regular-season TV ratings. A t...

29 Touko 57min

The Men Who Think Toxic Feminism Destroyed America

Over the past century, attitudes about gender roles have become one of the clearest dividing lines in the country. Many Republicans, both men and women, say men are getting a raw deal in modern Americ...

22 Touko 59min

Does Anybody Know How to Solve an American Debt Crisis?

On his 40th birthday, Derek Thompson takes a step back and looks at how his thinking on the national debt has changed. Back when he first covered fiscal policy, concern about government borrowing was ...

19 Touko 1h 1min

The Global Fertility Crisis Is Worse Than You Think

Fertility rates are collapsing around the world. In rich countries and poor ones, in secular societies and religious ones, people are having fewer children than ever before. Some explanations focus on...

15 Touko 1h 1min

The Case Against the AI Job Apocalypse

For the past few years, Silicon Valley executives and economists have warned that artificial intelligence could wipe out millions of jobs. Some companies have even blamed AI for layoffs. But what if t...

12 Touko 54min

Why American Happiness Just Fell Off a Cliff

America is richer than ever. Unemployment is low. Wages are high. According to traditional metrics, the economy looks strong. So why are Americans feeling so bad? Today, Derek talks with bestselling ...

8 Touko 1h

Why Too Much Freedom Is the Enemy of Success

Freedom is one of the few ideas everyone agrees on. Surely more choice and autonomy is a good thing, right? But what if our endless pursuit of freedom is actually making us more anxious, less creative...

1 Touko 49min