From seizures to Granulation Nation: The Unexpected Story of Phenytoin in Wound Healing
This episode traces how phenytoin — an anticonvulsant known for causing gingival overgrowth — was repurposed into a topical therapy for chronic wounds. It outlines the drug’s mechanisms in wounds: act...
13 Kesä 24min
Forgotten Infection Friday- Buruli Ulcer vs Diabetic Foot: Lessons from a Painless Wound
This episode explores the rare Buruli (Buruli) ulcer caused by Mycobacterium ulcerans and its toxin mycolactone, which destroys tissue, suppresses immune signaling, and reduces pain, leading to delaye...
12 Kesä 25min
Why we use Saline vs. Sterile Water vs. Tap Water vs Seawater- Not all water is equal
In this episode Dr. G explains why 0.9% sterile saline is the preferred when using to cleanse for diabetic foot ulcers, diving into osmosis, isotonicity, and how saline preserves cell function while...
11 Kesä 29min
Wound Intelligence Wednesday: Atraumatic Dressings for Diabetic Limbs
This episode explains traumatic dressing selection for diabetic wounds, emphasizing atraumatic (especially silicone-based) dressings that protect fragile peri-wound skin, preserve keratinocytes and ca...
10 Kesä 27min
Beyond Closure/ Post Healing Maintenance : Inside the Long Remodeling Phase of Wound Healing
Dr. G explains why skin closure in diabetic foot ulcers is a transition, not a cure: the remodeling phase can last months to years, leaving the scar biologically weaker and at high risk of recurrence....
9 Kesä 31min
Pentoxifylline: How a 'Blood-Flow' Drug Helps Diabetic Foot Ulcers
In this episode of Diabetic Foot Files Dr. G explores pentoxifylline — a decades-old methylxanthine drug — and how it improves microcirculation, reduces blood viscosity and inflammation, and may suppo...
8 Kesä 21min
The Hidden Thief: How Dehydration Stops Diabetic Foot Ulcer Healing
This episode explains how chronic dehydration—often overlooked in diabetic patients—slows blood flow, reduces oxygen and nutrient delivery, and stalls cellular repair, turning otherwise manageable foo...
7 Kesä 28min
Why Vaseline Can Be Dangerous for Diabetic Feet
This episode explains what Vaseline (petroleum jelly) does: it is an occlusive that seals moisture in but does not hydrate. It can soften intact dry skin but is unsafe for diabetic ulcers, macerated o...
6 Kesä 24min
