234 | Tobias Warnecke on Cellular Structure and Evolution

234 | Tobias Warnecke on Cellular Structure and Evolution

Eukaryotic cells manage to pull off a number of remarkable feats. One is packing quite a long DNA molecule, with potentially billions of base pairs, into a tiny central nucleus. A key role is played by histones, proteins that provide scaffolding for DNA to wrap around. Histones also appear in archaea (one of the other domains of life), but until recently there wasn't evidence for them in bacteria (the final of the three domains). Todays guest, Tobias Warnecke, is an author on a recent paper that claims to provide such evidence. We discuss this new result, as well as background questions of how cells evolved and what their current structure can teach us about their histories.

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Tobias Warnecke received his Ph.D. in biology from the University of Bath. He is currently a Programme Leader and MRC Investigator at the London Institute of Medical Sciences. He is a co-author on A. Hochner et al. (2023), "Histone-Organized Chromatin in Bacteria."


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Jaksot(411)

214 | Antonio Padilla on Large Numbers and the Scope of the Universe

214 | Antonio Padilla on Large Numbers and the Scope of the Universe

It’s a big universe we live in, so it comes as no surprise that big numbers are needed to describe it. There are roughly 10^22 stars in the observable universe, and about 10^88 particles altogether. B...

17 Loka 20221h 15min

AMA | October 2022

AMA | October 2022

Welcome to the October 2022 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pat...

10 Loka 20223h 1min

213 | Timiebi Aganaba on Law and Governance in Space

213 | Timiebi Aganaba on Law and Governance in Space

With communication satellites, weather satellites, GPS, and much more, what happens in space is already important to our lives here on Earth. And the importance of space is only going to grow as we in...

3 Loka 20221h 16min

212 | Chiara Mingarelli on Searching for Black Holes with Pulsars

212 | Chiara Mingarelli on Searching for Black Holes with Pulsars

The detection of gravitational waves from inspiraling black holes by the LIGO and Virgo collaborations was rightly celebrated as a landmark achievement in physics and astronomy. But ultra-precise grou...

26 Syys 20221h 26min

211 | Solo: Secrets of Einstein's Equation

211 | Solo: Secrets of Einstein's Equation

My little pandemic-lockdown contribution to the world was a series of videos called The Biggest Ideas in the Universe. The idea was to explain physics in a pedagogical way, concentrating on establishe...

19 Syys 20221h 51min

210 | Randall Munroe on Imagining What If...?

210 | Randall Munroe on Imagining What If...?

What’s the fastest way to get a human being around a racetrack, if we ignore all the rules of racing? How many pages would you have to read to absorb all of the government laws that apply to you? It’s...

12 Syys 20221h 8min

209 | Brad DeLong on Why the 20th Century Fell Short of Utopia

209 | Brad DeLong on Why the 20th Century Fell Short of Utopia

People throughout history have imagined ideal societies of various sorts. As the twentieth century dawned, advances in manufacturing and communication arguably brought the idea of utopia within our pr...

5 Syys 20221h 24min

AMA | September 2022

AMA | September 2022

Welcome to the September 2022 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by P...

29 Elo 20223h 30min

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