Glasgow Neuro-2022; YNSS; Ericka Mejia Farias;  Immunotherapy
SNI Digital Podcast15 Marras 2023

Glasgow Neuro-2022; YNSS; Ericka Mejia Farias; Immunotherapy

SUMMARY: This project was performed at the University College of London in the Cancer Institute with the contribution of other scientists. Simple Summary: In the tumor micro environment in the brain there are immune cells which attack the tumor cell and those which protect it from attack. The authors use an agent which prevents the protecting immune cells from stopping the attacking immune cells from destroying the tumor and its foreign proteins. As a result the tumor is destroyed by the patient's own immune cells. The authors state that these counteracting immune systems extend to the human species. Thus, the drug treatment should be able to work to allow human glioblastoma cells to be destroyed. This report is about the animal studies. A very interesting new approach to glioblastoma treatment. Look for more publications on this subject.- JIA The authors' summary is: scRNa-seq and FACS analysis confirmed RG629-treatment in our mouse model depleted Tregs, likely through an Fc-gamma-receptor-mediated mechanism involving phagocytic-myeloid cells, and depleted tumour cells through enhanced clonal expansion of CD8 T cells. Conservation of Treg signatures between species suggest that the strong RG6292 treatment-effect observed in our GBM mouse model could be translated to clinic in the future and provide much-needed treatment for GBM patients.

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Jaksot(150)

Exposure to Neurosurgery Among Undergraduate Medical Students in Europe: A Scoping Review; Tejas A. Sawant;

Exposure to Neurosurgery Among Undergraduate Medical Students in Europe: A Scoping Review; Tejas A. Sawant;

SUMMARY: Methods: The PRISMA extension for Scoping Reviews (PRISMA-ScR) was used as a reference to guide the search strategy. PubMed was the primary database used to search for articles about “Neurosu...

7 Kesä 24min

Exposure to Neurosurgery Among Undergraduate Medical Students in Europe: A Scoping Review; Tejas A. Sawant;

Exposure to Neurosurgery Among Undergraduate Medical Students in Europe: A Scoping Review; Tejas A. Sawant;

SUMMARY: Methods: The PRISMA extension for Scoping Reviews (PRISMA-ScR) was used as a reference to guide the search strategy. PubMed was the primary database used to search for articles about “Neurosu...

7 Kesä 23min

CP Angle: Extracranial Approaches; Dr. Dennis Malkasian; Part 1

CP Angle: Extracranial Approaches; Dr. Dennis Malkasian; Part 1

SUMMARY: Dr. Dennis Malkasian, Neurosurgeon, Anatomist and Molecular biologist reviews the Surgical Anatomy of the CP ANGLE for Neurosurgeons approaching this area for the treatment of tumors there. A...

7 Kesä 1h 25min

Cauda Equina Neuroendocrine Tumour of the Filum Terminale: A Case Report and Summary of the Literature; Glasgow Neuro Meeting Video Abstracts; Theoklis Kouyialis; Christophoros Christophorou, Christina Oxinou, Demetris Fkiaras.

Cauda Equina Neuroendocrine Tumour of the Filum Terminale: A Case Report and Summary of the Literature; Glasgow Neuro Meeting Video Abstracts; Theoklis Kouyialis; Christophoros Christophorou, Christina Oxinou, Demetris Fkiaras.

SUMMARY: Cauda Equina Neuroendocrine tumours (CENETs), previously known as Cauda Equina Paragangliomas (PGLs), are extremely rare vascular tumours of the spine which are mostly benign, slow-growing an...

7 Kesä 24min

Natural History of Pineal Cysts: A Retrospective Cohort Study;  Yihui Cheng; Glasgow Neuro Meeting Video Abstracts; 2025-2026; Xin Y. Yap, Zahraa Dashti, Steven Tominey, Kevin Owusu-Agyemang, Edward J. St George.

Natural History of Pineal Cysts: A Retrospective Cohort Study; Yihui Cheng; Glasgow Neuro Meeting Video Abstracts; 2025-2026; Xin Y. Yap, Zahraa Dashti, Steven Tominey, Kevin Owusu-Agyemang, Edward J. St George.

SUMMARY: " Pineal cysts (PCs) are frequently identified incidentally on neuroimaging, yet their clinical significance was thought to be benign. While most remain stable, concerns persist regarding the...

7 Kesä 28min

The Impact of a Webinar Series on Student Perspectives to Neuroscience Research Barriers; Emilia Parsi, Alsadeg Bilal, Selnan Wuyep, Chandru Kaliaperumal; Glasgow Neuro Meeting Video Abstracts;

The Impact of a Webinar Series on Student Perspectives to Neuroscience Research Barriers; Emilia Parsi, Alsadeg Bilal, Selnan Wuyep, Chandru Kaliaperumal; Glasgow Neuro Meeting Video Abstracts;

SUMMARY: "Background: Research engagement amongst medical students tends to be minimal until it becomes a curricular requirement, and the specific barriers to early involvement remain unclear. The Gen...

7 Kesä 23min

Young Neurosurgeons Discussions with the Experts; EC-IC Bypass Surgery 1980-2025

Young Neurosurgeons Discussions with the Experts; EC-IC Bypass Surgery 1980-2025

SUMMARY: Drs. Nussbaum and Ausman discuss with Dr. Rennert the years of experience with EC -IC Bypass surgery. For Ischemia the major issue was the 1985 EC-IC Bypass Study, a RCT that was scientifica...

25 Touko 1h 14min

How we built a Stroke Center program in a LMIC for 160 million people? Qasim Bashir; Asif Bashir

How we built a Stroke Center program in a LMIC for 160 million people? Qasim Bashir; Asif Bashir

SUMMARY: Dr. Qasim Bashir, a Board certified Neurologist, Intensivist, Interventionist returned to Pakistan, a LMIC, after studying outside his country for 16 years to help develop healthcare in Punja...

25 Touko 1h 10min

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