#673: Dr. Nora Volkow — Director of the National Institute on Drug Abuse (NIDA)

#673: Dr. Nora Volkow — Director of the National Institute on Drug Abuse (NIDA)

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Nora D. Volkow, MD, is Director of the National Institute on Drug Abuse (NIDA) at the National Institutes of Health. NIDA is the world’s largest funder of scientific research on the health aspects of drug use and addiction. Dr. Volkow's work has been instrumental in demonstrating that drug addiction is a brain disorder. As a research psychiatrist, Dr. Volkow pioneered the use of brain imaging to investigate how substance use affects brain functions. In particular, her studies have documented how changes in the dopamine system affect the functions of brain regions involved with reward and self-control in addiction. She has also made important contributions to the neurobiology of obesity, ADHD, and aging.

Please enjoy!

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This episode is also brought to you by House of Macadamias delicious and nutritious nuts! I love macadamia nuts and have been enjoying them often since keto expert Dr. Dominic D’Agostino recommended them on the podcast in 2015. They taste great, and with more healthy, monounsaturated fat than both olive oil and avocados, 27% fewer carbs than almonds, and more than 50% fewer carbs than cashews, they’re the perfect low-carb, keto-friendly, nutty snack. In fact, I just ate a handful of lightly white-chocolate-covered macadamias about an hour ago to keep me going through the afternoon until dinner. And I will say this: ​House of Macadamias produces the best-tasting macadamia nuts I’ve ever eaten… by far.

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[06:09] Cadaver homework.

[09:07] The Trotsky connection.

[17:07] How Nora’s father viewed the role of science.

[20:59] Julian Villarreal.

[27:38] A perspective of perseverance.

[33:48] Instilling perseverance in younger scientists.

[35:08] Dancing with Demerol.

[40:05] The current state of addiction in the US.

[44:28] The War on Drugs.

[49:42] Increasing societal confidence in therapeutic psychedelics.

[55:38] Advice for researchers seeking more federal funding.

[1:02:12] Gauging the value of the hallucinogenic experience.

[1:06:04] Implications for multiple applications of one compound.

[1:13:36] Transcranial magnetic stimulation (TMS) and a promising alternative.

[1:19:49] New hope for Parkinson’s disease sufferers?

[1:23:51] Comorbidities, addiction considerations, and other parting thoughts.

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Past guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.

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#831: Frank Miller, Comic Book Legend — Creative Process, The Dark Knight Returns, Sin City, 300, and Much More

#831: Frank Miller, Comic Book Legend — Creative Process, The Dark Knight Returns, Sin City, 300, and Much More

Frank Miller is regarded as one of the most influential and awarded creators. He began his career in comics in the late 1970s, first gaining notoriety as the artist, and later writer, of Daredevil for...

20 Loka 20251h 32min

#830: Nick Kokonas and Richard Thaler, Nobel Prize Laureate — Realistic Economics, Avoiding The Winner’s Curse, Using Temptation Bundling, and Going Against the Establishment

#830: Nick Kokonas and Richard Thaler, Nobel Prize Laureate — Realistic Economics, Avoiding The Winner’s Curse, Using Temptation Bundling, and Going Against the Establishment

Richard H. Thaler is the 2017 recipient of the Nobel Memorial Prize in Economic Sciences for his contributions to behavioral economics and the Charles R. Walgreen Distinguished Service Professor of Be...

10 Loka 20251h 57min

#829: James Nestor — Breathing Protocols to Reboot Your Health, Fix Your Sleep, and Boost Performance

#829: James Nestor — Breathing Protocols to Reboot Your Health, Fix Your Sleep, and Boost Performance

James Nestor is a science journalist and the author of the international bestseller Breath: The New Science of a Lost Art, with more than three million copies sold in 44 languages.This episode is brou...

30 Syys 20251h 50min

#828: David Senra — How Extreme Winners Think and Win: Lessons from 400+ of History’s Greatest Founders and Investors (Including Buffett, Munger, Rockefeller, Jobs, Ovitz, Zell, and Names You Don’t Know But Should)

#828: David Senra — How Extreme Winners Think and Win: Lessons from 400+ of History’s Greatest Founders and Investors (Including Buffett, Munger, Rockefeller, Jobs, Ovitz, Zell, and Names You Don’t Know But Should)

David Senra is the host of the Founders podcast. For the past nine years, David has intensely studied the life and work of hundreds of history’s greatest entrepreneurs. His new podcast, David Senra, s...

24 Syys 20252h 55min

#827: Pablos Holman — One of The Scariest Hackers I’ve Ever Met

#827: Pablos Holman — One of The Scariest Hackers I’ve Ever Met

Pablos Holman is a hacker and inventor and the author of Deep Future: Creating Technology that Matters, the indispensable guide to deep tech. Previously, Pablos worked on spaceships at Blue Origin and...

16 Syys 20252h 31min

#826: Q&A with Tim — Supplements I’m Taking, Austin vs. SF, Training for Mental Performance, Current Go-To AI Tools, Recovering from Surgery, Intermittent Fasting, and More

#826: Q&A with Tim — Supplements I’m Taking, Austin vs. SF, Training for Mental Performance, Current Go-To AI Tools, Recovering from Surgery, Intermittent Fasting, and More

This episode is a solo Q&A session where I answer a bunch of questions. We covered a ton of ground, from personal health protocols to professional frameworks and creative projects. This episode is bro...

9 Syys 20251h 25min

#825: Dr. Dominic D’Agostino — All Things Ketones, How to Protect the Brain and Boost Cognition, Sardine Fasting, Diet Rules, Revisiting Metformin and Melatonin, and More

#825: Dr. Dominic D’Agostino — All Things Ketones, How to Protect the Brain and Boost Cognition, Sardine Fasting, Diet Rules, Revisiting Metformin and Melatonin, and More

Dr. Dominic D’Agostino (@DominicDAgosti2) is a tenured associate professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine and...

3 Syys 20251h 54min

#824: What Most Has My Attention Right Now — Credible (vs. Bogus) Vagus Nerve Stimulation

#824: What Most Has My Attention Right Now — Credible (vs. Bogus) Vagus Nerve Stimulation

Kevin J. Tracey, MD is president and CEO of the Feinstein Institutes for Medical Research at Northwell Health, a pioneer of vagus nerve research and author of the recent book, The Great Nerve: The New...

26 Elo 20252h 23min

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