Changing the Patient Experience with Therapeutic Plasma Exchange: A Florida Nurse’s Perspective
TPE Blueprint23 Syys 2025

Changing the Patient Experience with Therapeutic Plasma Exchange: A Florida Nurse’s Perspective

In this uplifting and insightful episode, host Joe Fier sits down with Mitch Velez-Zumbrunn, a clinical apheresis nurse spearheading Therapeutic Plasma Exchange (TPE) treatments at MDLifespan’s first clinic in Florida. Mitch shares an inside look at the patient journey, what makes TPE unique, and some of the transformative results he’s witnessed firsthand. The conversation ranges from practical details about the treatment process and overcoming patient anxieties, to the importance of toxin education and the supportive network driving MDLifespan’s mission. Whether you’re curious about TPE protocols, intrigued by detoxification, or just want to hear how frontline care is evolving, this episode delivers the goods.

Topics Discussed

  • Mitch’s Nursing Journey: From ER nursing and travel assignments to pediatric care and apheresis specialization, Mitch shares his career path and what led him to TPE.
  • What is TPE? An accessible explanation likened to an “oil change for the body”—what it does, how it works, and how it differs from procedures like dialysis and blood donation.
  • Patient Experience: Step-by-step walkthrough of a typical TPE session, addressing common patient concerns, preparation, and what to expect before, during, and after treatment.
  • Results and Surprises: Real-life stories about patient improvements, from renewed senses to decreased inflammation and increased energy—plus the variety of responses TPE can produce.
  • Toxins and Regional Trends: The types of toxins commonly seen in Florida, like pesticides and chemicals from plastics, and how environment and lifestyle impact toxin buildup.
  • The Importance of Vascular Access Skills: Why advanced ultrasound IV skills are crucial for a successful and comfortable TPE experience.
  • Overcoming Needle Anxiety: How Mitch helps patients relax—using cold sprays, supportive communication, and building confidence both in technology and technique.
  • Post-TPE Follow-Up: Details on aftercare, including communication with patients, testing protocols (objective labs and subjective quality of life surveys), and what patients might feel in the days after treatment.
  • Lifestyle and Education: Tips on reducing toxin exposure at home, plus how the MDLifespan team educates and supports patients beyond the clinic visit.
  • The Future of TPE: Mitch’s excitement about ongoing research, the growth of educational resources, and the promising direction of preventative care.

Connect with Us


If you found this episode insightful, be sure to subscribe to TPE Blueprint wherever you listen and leave us a review! Share the episode with friends or family who might benefit from learning about TPE and holistic detox. Your support helps us bring more frontline stories and health breakthroughs to the community.

Disclaimer:

MDLifespan PlasmaXchange protocols are designed to support general health and wellness. They are not intended to diagnose, treat, cure, or prevent any disease. The information provided on this podcast is for educational purposes only and should not replace medical advice. Please consult with your healthcare provider before beginning any new health program, especially if you have a medical condition or are taking prescribed medications.

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