The Ketogenic Diet with Dr. Dominic D'Agostino

In this episode of the Dr. Layne Norton Podcast, Layne sits down with renowned researcher and ketogenic diet expert Dr. Dominic D’Agostino to dive deep into the science of the ketogenic diet. Professor Dominic D’Agostino (University of South Florida Morsani College of Medicine / Institute for Human and Machine Cognition) is one of the leading voices on nutritional ketosis, exogenous ketones, and metabolic therapies. Together, they unpack what the research actually shows about keto – beyond the hype and social media claims.

They cover the mechanisms of ketosis, potential therapeutic applications (including epilepsy, metabolic health, neurological conditions, and ongoing research areas like cancer support), practical considerations for implementing a well-designed ketogenic approach, common misconceptions, protein and micronutrient needs, exogenous ketones, and how keto stacks up for fat loss, performance, and long-term adherence compared to other dietary strategies. Expect an evidence-based, no-BS conversation that prioritizes data over dogma.

#KetogenicDiet #Keto #DominicDAgostino #LayneNorton #NutritionScience #MetabolicHealth #EvidenceBasedNutrition #DrLayneNortonPodcast

SPONSORS

• David Protein - Buy 4 cartons, get 1 FREE at: https://davidprotein.com/pages/layne

• REPS Research Review: https://biolayne.com/reps

LAYNE'S COMPANIES

Carbon Diet Coach: https://joincarbon.com/podcast

Outwork Nutrition: https://outworknutrition.com

REPS Research Review: https://biolayne.com/reps

Workout Builder: https://biolayne.com/workout-builder

Team Biolayne: https://biolayne.com/online-coaching

Physique Coaching Academy: https://physiquecoachingacademy.com

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TIMESTAMPS

0:00:00 - Intro

0:02:37 - Dom's Background

0:05:57 - Ketones and Seizures

0:15:23 - Animal Research

0:18:42 - David Protein

0:20:17 - Mechanisms of Ketone Therapy

0:28:07 - Magnesium

0:29:12 - Dementia/Alzheimers

0:37:55 - Cancer

0:45:38 - REPS Research Review

0:46:29 - Cancer Cont.

1:16:50 - Muscle Hypertrophy

1:27:55 - Fasting

1:38:33 - Training

2:01:42 - Ranking Importance

2:04:34 - Last Question

2:20:13 - Outro

SHOW NOTES

https://biolayne.com/podcasts/dr-layne-norton-podcast/the-ketogenic-diet-with-dr-dominic-dagostino-episode-34