#132 DTC Series: Michael Schnall-Levin on Single Cell Sequencing

#132 DTC Series: Michael Schnall-Levin on Single Cell Sequencing

Exciting Announcement: This week “DNA Today” won the Best 2020 Science and Medicine Podcast in The 15th Annual Podcast Awards! This is thanks to each and every listener who nominated and voted for the show. THANK YOU for being such loyal listeners for the past 8 years. We’ve been nominated for four years, and it’s incredible to win this year! For those that aren’t familiar, The Podcast Awards are the longest running podcast awards event open to shows worldwide, this year there was 250,000 people who nominated shows.

Michael Schnall-Levin joins host Kira Dineen on this episode to explore genetic testing technology including next-gen sequencing, single cell sequencing and bioinformatics. This episode is part 6 of our ongoing direct-consumer genetic testing series, check out our previous episodes for other deep dives into DTC topics.

Michael is the Senior Vice President President of Product, Research and Development and Founding Scientist at 10x Genomics. Before joining 10x Genomics, Michael was an NSF postdoctoral fellow with Eric Lander at the Broad Institute where he worked on developing novel applications of DNA sequencing technologies. Prior to that, Michael worked at Foundation Medicine, where he developed some of the early algorithms to accurately detect mutations in patient tumor samples. Michael earned his PhD in Mathematics from MIT with Bonnie Berger, where he was both a Hertz fellow and NDSEG fellow, and his BA in Physics from Harvard College.

On This Episode We Discuss:

Steps to Sequence DNA/RNA

Sanger and Next Gen Sequencing

Single Cell Sequencing

Process, Accuracy, Advantages

Ultiziting in Cancer, Immunotherapy

Bioinformatics

Future of Genetic Testing

Learn more about 10X Genomics on their website, Twitter and Facebook.

Picture Genetics is our sponsor for this DTC genetic testing series and offers a unique DNA testing service. These tests are designed for every stage of life, from family planning and newborn health, to personal wellness and disease risk. Unlike other companies, this is actually a clinical grade test where physicians and genetic counselors are involved. The test sequences entire genes that are medically actionable. It’s easy to order and understand with good looking reports! To order your Picture Genetics go to picturegenetics.com and use code “DNATODAY” for 25% off and free-shipping! Get actionable genetic insights today to benefit your family of tomorrow.

Stay tuned for the next new episode of DNA Today on October 23th where we continue our direct-to-consumer genetic testing podcast series! New episodes are released on the first and third Friday of the month. In the meantime, you can listen to over 130 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”.

See what else we are up to on Twitter, Instagram, Facebook and iTunes. Questions/inquiries can be sent to info@DNApodcast.com.

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Jaksot(412)

#411 Mock Cancer Genetic Counseling Session: Colon Cancer and Lynch Syndrome

#411 Mock Cancer Genetic Counseling Session: Colon Cancer and Lynch Syndrome

What happens during genetic counseling after someone develops colon cancer at a young age and their tumor testing raises concern for Lynch syndrome? This is the eighth installment in our Mock Genetic ...

11 Syys 30min

#410 Gypsy Rose Blanchard’s 1q21.1 Microdeletion: What Does It Explain?

#410 Gypsy Rose Blanchard’s 1q21.1 Microdeletion: What Does It Explain?

This episode drop from the PRETEND podcast series “The Gypsy Rose Obsession” features Kira Dineen explaining what Gypsy Rose Blanchard’s genetic test result may, and may not, mean. Gypsy Rose Blanchar...

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#409 How DNA Testing Exposed the Dark History of American Adoption

#409 How DNA Testing Exposed the Dark History of American Adoption

What happens when stigma, secrecy, and institutional power separate a mother from her child, and prevent an adoptee from accessing his own identity and medical history for decades? This week, we are s...

28 Elo 43min

#408 Low ALP, Fractures, and Early Tooth Loss Point to Hypophosphatasia

#408 Low ALP, Fractures, and Early Tooth Loss Point to Hypophosphatasia

Hypophosphatasia (HPP) can present very differently from one person to the next, from life-threatening complications in infancy to fractures, chronic pain, muscle weakness, or early tooth loss later i...

21 Elo 37min

#407 NFL and Kansas City Chiefs Star Art Still on the Missed Signs of Hereditary Amyloidosis

#407 NFL and Kansas City Chiefs Star Art Still on the Missed Signs of Hereditary Amyloidosis

What happens when the symptoms of a genetic condition look like the lasting effects of a professional football career? Former NFL defensive end and Kansas City Chiefs star Art Still spent decades attr...

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#406 Mock Teratogen Genetic Counseling Session: Ozempic, Zoloft, Xanax, and Metformin

#406 Mock Teratogen Genetic Counseling Session: Ozempic, Zoloft, Xanax, and Metformin

This is our seventh installment in our Mock Genetic Counseling Session Series! In this episode, genetic counselor and teratogen information specialist Sharon Voyer Lavigne and student Edith Atwerebour...

7 Elo 30min

#405 Why Insurance Denies Genetic Testing, and How to Navigate Coverage

#405 Why Insurance Denies Genetic Testing, and How to Navigate Coverage

Genetic testing can change the course of a patient’s care, but accessing the right test is not always straightforward. Behind the scenes, insurance coverage decisions, documentation requirements, prio...

31 Heinä 34min

#404 Male Breast Cancer with X-Men Actor and Former Pro Wrestler Tyler Mane

#404 Male Breast Cancer with X-Men Actor and Former Pro Wrestler Tyler Mane

What happens when someone known for strength, stature, and intimidating roles faces a diagnosis most people do not associate with men?   Tyler Mane is known for playing Sabretooth in X-Men and Deadpoo...

24 Heinä 21min

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