Isabella Cooper – Part 1 – The Chemical Removed From Tampons Is Still in Most Diapers

Isabella Cooper – Part 1 – The Chemical Removed From Tampons Is Still in Most Diapers

In this episode of The Feldman Protocol, what does beta-hydroxybutyrate between meals actually reveal about a person's insulin state — and why might that matter for understanding chronic disease risk? Dave sits down with Isabella Cooper (PhD), a biochemistry and pathophysiology scientist whose research spans assay quality control, hyperinsulinemia detection, ketone thresholds, mitochondrial function, and the lipid energy model, making the case that personalized insulin thresholds — not population-wide cutoffs — may be key to identifying subclinical metabolic dysfunction.🔥 This episode is sponsored by us --Own Your Labs 👉 `https://ownyourlabs.com/sp/48` Private blood testing services🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters0:00 – Cold open & intro1:06 – Isabella's background & credentials3:05 – East-meets-West medicine upbringing5:43 – Ballet, modeling & low-carb insights6:36 – Industrial design degree & lab thinking8:58 – Assay quality problems in undergrad lab12:08 – Coefficient of variation explained17:01 – Standardizing vortex & sample handling27:30 – Back to timeline: the 15-year gap39:52 – Pregnancy, diapers & toxicology deep dive53:06 – Old physiology papers vs modern science1:00:05 – Osteocalcin hypothesis & being wrong1:06:48 – Ben Bikman, mitochondria & insulin1:19:40 – Headwinds for low-carb research1:34:19 – Personalized insulin threshold concept1:41:28 – Beta-hydroxybutyrate as insulin surrogate1:51:44 – Leptin, IGF-1 & multi-marker detection2:09:09 – Subclinical hyperinsulinemia marker cluster2:14:20 – Fasting, lipid dynamics & VLDL traffic#FeldmanProtocol #DaveFeldman #IsabellaCooper #Hyperinsulinemia #Ketosis #Mitochondria #MetabolicHealth #InsulinResistance #BetaHydroxybutyrate #LowCarb #ChronicDisease #LipidEnergyModel #AssayQuality #KetoneThreshold #LaboratoryScience #Bioenergetics #BloodTesting #Inflammation

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Arthur Agatston (Part 3) on Insulin Resistance, LP(a), and Why He Went Militantly Keto

Arthur Agatston (Part 3) on Insulin Resistance, LP(a), and Why He Went Militantly Keto

In this episode of The Feldman Protocol, how does metabolic health shape cardiovascular risk — and does the conventional focus on individual biomarkers miss the bigger picture? Dave Feldman sits down ...

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Dr. Arthur Agatston (Part 2) - Why Did Most Keto Patients Show Zero Plaque Despite LDL of 250?

Dr. Arthur Agatston (Part 2) - Why Did Most Keto Patients Show Zero Plaque Despite LDL of 250?

In this episode of The Feldman Protocol, how does metabolic health shape cardiovascular risk — and what does that mean for interpreting cholesterol markers in lean, low-carb individuals? Arthur Agatst...

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The Stent Myth: Why Fixing a Blockage Isn’t a Cure - Dr. Arthur Agatston

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In this episode of The Feldman Protocol, how well do conventional cardiovascular risk metrics actually identify who is truly at risk for a heart attack decades before it happens? Cardiologist Arthur A...

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Isabella Cooper – Part 2 – Ketogenic Diet and Cancer: What the Science Actually Shows

Isabella Cooper – Part 2 – Ketogenic Diet and Cancer: What the Science Actually Shows

In this episode of The Feldman Protocol, how does insulin influence cancer cell behavior — and what does that mean for metabolic approaches to the disease? Dave sits down with Isabella Cooper (PhD) to...

11 Syys 1h 56min

Dr Scott Murray – Is IVUS Plaque ‘Regression’ Just Measurement Noise?

Dr Scott Murray – Is IVUS Plaque ‘Regression’ Just Measurement Noise?

In this episode of The Feldman Protocol, how much does metabolic health shape cardiovascular risk beyond what standard lipid markers can reveal? Dave Feldman sits down with Scott Murray (MD), a UK-bas...

4 Syys 3h 28min

Darius Sharp – Pt 2 – What Happens to Your Lipids After 2,000 Calories of Fat?

Darius Sharp – Pt 2 – What Happens to Your Lipids After 2,000 Calories of Fat?

In this episode of The Feldman Protocol, what actually drives cardiovascular disease in a metabolically healthy, lean individual — and is elevated LDL the most important variable to consider? Darius S...

1 Syys 2h 40min

Dr. Malcolm Kendrick – The Country With the Lowest Cholesterol and the Highest Heart Disease Rate

Dr. Malcolm Kendrick – The Country With the Lowest Cholesterol and the Highest Heart Disease Rate

In this episode of The Feldman Protocol, how well does the prevailing understanding of LDL and cardiovascular disease hold up under close scrutiny? Dave sits down with Malcolm Kendrick (MD) — author, ...

31 Elo 3h 35min

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