Ep 131 Parkinson’s Disease: Dopamine & discoveries

Ep 131 Parkinson’s Disease: Dopamine & discoveries

Parkinson’s is a disease of many dimensions. On the shelves of any bookstore or library you’ll find at least a handful of titles exploring the topic from a myriad of perspectives, and extending that search to the internet will turn up dozens upon dozens more options: how-to guides for the recently diagnosed, in-depth textbooks exploring the neurophysiology of disease development, memoirs about caregiving for people with Parkinson’s, books offering a tour through the history of research advancements. The choices seem limitless and maybe a tad overwhelming. But that’s where we come in. In this episode, we take you through many of the dimensions of Parkinson’s disease, from its complicated biology, still shrouded in mystery, to its history, peppered with transformative moments like the introduction of dopamine. We round out the episode by exploring the tremendous amount of promising research on the horizon, leaving us feeling like we’re *this* close to yet another revolution in Parkinson’s disease treatment. If you’ve ever wondered what dopamine does, who Parkinson was, and what might be next for this disease, this episode is for you.

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Jaksot(282)

Ep 187 Hypothermia Part 2: How it helps

Ep 187 Hypothermia Part 2: How it helps

Last week, we took you through all the ways that cold can harm us and the harrowing history of humans perishing at its icy hands. Ending the story there would be skipping over the parts where cold get...

9 Syys 20251h 5min

Ep 186 Hypothermia Part 1: How it hurts

Ep 186 Hypothermia Part 1: How it hurts

For all our wondrous adaptations as a species - our big brains, our capacity for language, our opposable thumbs - we humans are not well-equipped to deal with the cold. Take us out of our insulated dw...

2 Syys 202557min

Special Episode: Lina Zeldovich & The Living Medicine

Special Episode: Lina Zeldovich & The Living Medicine

The development of antibiotics was one of the greatest turning points in the history of medicine. Bacterial infections that were once death sentences were cured within a matter of days after administr...

26 Elo 202551min

Ep 185 The Great Smog of London: “Thick, drab, yellow, disgusting”

Ep 185 The Great Smog of London: “Thick, drab, yellow, disgusting”

Some things just go together: peanut butter and jelly, bacon and eggs, milk and cereal, London and smog. Or at least, that’s the way things used to be until the Great Smog of 1952. (Don’t worry, the f...

19 Elo 20251h 14min

Ep 184 The Gallbladder: Humor us

Ep 184 The Gallbladder: Humor us

For most of us, there probably hasn’t been a good reason for you to think about your gallbladder. Ever. Much of the time, it sits there, silently storing, concentrating, and, when needed, churning out...

12 Elo 20251h 22min

Special Episode: Carl Zimmer & Airborne

Special Episode: Carl Zimmer & Airborne

In the first years of the COVID pandemic, a debate raged: was the virus transmitted via respiratory droplets, or was it airborne? For some, this distinction seemed overly technical, pedantic even. But...

5 Elo 202549min

Ep 183 SSRIs Part 2: Action

Ep 183 SSRIs Part 2: Action

Last week, we took you on a journey of discovery and innovation, and this week we’re gonna tell you how the heck it all works. That means a deep dive into the nitty gritty of SSRIs, from what serotoni...

29 Heinä 20251h 10min

Ep 182 SSRIs Part 1: Origin

Ep 182 SSRIs Part 1: Origin

Since first hitting the shelves nearly 40 years ago, SSRIs have become one of the most commonly prescribed classes of antidepressants around the world, as well as one of the most discussed and misunde...

22 Heinä 20251h 2min

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