618: Methylation, Epigenetics & Longevity with Steve Horvath

618: Methylation, Epigenetics & Longevity with Steve Horvath

Kane Tanaka of Japan died in 2022 at the age of 119. Lucile Randon of France died in 2023 at 118. Jiroemon Kimura of Japan died in 2023 at 116, the oldest male ever. What did these people have in common? Were they biohackers? Did they do CrossFit? Did they take NAD supplements or run marathons? Nope. Like almost all centenarians they lived exceptionally long lives most-likely due to genetics, combined with a moderately healthy or even average healthy lifestyle. Despite the overwhelming abundance of evidence that we're all going die sooner rather than later, the quest for longevity never stops. My guest on this week's podcast has developed a unique way to measure biological age and his work is playing a key role in longevity research and biohacker communities.

Listen and learn:

  • The overlooked role of epigenetics in your health and lifespan
  • Biohackers, science fiction, and the reality of living a long time
  • How methylation patterns can be predictive of lifespan
  • The significance of GrimAge for reducing early mortality

Links

Steve on X

ABOUT OUR GUEST

Steve Horvath is a German-American researcher, geneticist, and biostatistician. He is a professor at UCLA and the principal investigator at Altos Labs, specializing in epigenetic biomarkers of aging, genomics, and comparative biology.

Like the Show?

Jaksot(668)

642: The Health Benefits of Muscle with Dan van den Hoek

642: The Health Benefits of Muscle with Dan van den Hoek

When you think about healthspan and longevity, your first thought probably isn't "muscle" - but it should be. Here are just some of the benefits of muscle strength and mass, particularly as you age: i...

16 Loka 202439min

641: Understanding Fiber and Gut Health with Dr. Will Bulsiewicz

641: Understanding Fiber and Gut Health with Dr. Will Bulsiewicz

Fiber is often overlooked in discussions about diet, weight loss, and immunity, but it shouldn't be. Fiber is essential for digestive health, improving gut motility, and regulating bowel movements. It...

9 Loka 202434min

640: Understanding Chronic Pain with Dr. David Clarke

640: Understanding Chronic Pain with Dr. David Clarke

Chronic pain affects hundreds of millions worldwide, with conditions like gastrointestinal issues, back pain, and migraine topping the list. In many cases, psychological factors play a significant rol...

2 Loka 202443min

639: Weight Loss Bankruptcy with Lucas Rockwood

639: Weight Loss Bankruptcy with Lucas Rockwood

The iconic brand Tupperware filed for bankruptcy this week, burdened with over $1.2 billion of debt. They've reached a point of no return, where digging out is virtually impossible. In many ways, this...

26 Syys 202430min

638: Brain Talk with Dr. Jesse Rissman

638: Brain Talk with Dr. Jesse Rissman

Neuroscience might be the final frontier when it comes to the human body. There is still so much to be discovered and understood about memory, attention, and how we learn. My guest on this week's podc...

18 Syys 202442min

637: Telomeres and Aging with Dr. Richard Allsopp

637: Telomeres and Aging with Dr. Richard Allsopp

You know how old you are, but do you know your biological age? Meaning, are your body and brain younger or older than your chronological years? For anyone interested in slowing down aging and preventi...

11 Syys 202439min

636: Understanding Sleep with Dr. Ketema Paul

636: Understanding Sleep with Dr. Ketema Paul

Sleep is as vital for life as food, water, and breathing, but knowing its importance doesn't necessarily provide you with the tools to improve it. What if you toss and turn and can't sleep until late?...

4 Syys 202440min

635: Understanding the Gut Microbiome with Dr. Gregor Reid

635: Understanding the Gut Microbiome with Dr. Gregor Reid

Inside your gastrointestinal tract there are trillions of microbes, about 3 lbs in total, and in terms of absolute numbers, you have more microbial cells than human cells. This collection of bacteria,...

28 Elo 202445min

Suosittua kategoriassa Koulutus

rss-murhan-anatomia
voi-hyvin-meditaatiot-2
psykopodiaa-podcast
rss-narsisti
adhd-podi
rss-liian-kuuma-peruna
aamukahvilla
rss-rahamania
rss-eron-alkemiaa
kesken
rss-duodecim-lehti
rss-koira-haudattuna
rahapuhetta
rss-tietoinen-yhteys-podcast-2
rss-niinku-asia-on
rss-uskonto-on-tylsaa
rss-onks-ok
rss-turun-yliopisto
rss-vapaudu-voimaasi
rss-finnish-daily-dialogues