235 - Menopause and brain health: what’s the link?

235 - Menopause and brain health: what’s the link?

In this episode Dr Louise is joined by world-renowned neuroscientist Dr Lisa Mosconi, PhD. Dr Lisa is Director of the Alzheimer’s Prevention Clinic and Women’s Brain Initiative at Weill Cornell Medicine in New York and author of bestsellers The XX Brain and Brain Food.

Dr Lisa was studying nuclear medicine and neuroscience when her grandmother and her grandmother’s three sisters all developed Alzheimer's. Dr Lisa became interested in the cause of Alzheimer’s and why women are more susceptible. Her research has shown that, rather than a disease of old age, it starts in midlife and menopause potentially plays a part.

Dr Lisa discusses her most recent paper, which found that women who took hormones in midlife to treat their menopause symptoms were less likely to develop dementia than those who hadn’t taken oestrogen.

Finally, Dr Lisa shares three things to consider about female hormones:

  1. Oestrogen, and oestradiol in particular, is the master regulator of women's brains. It really is like saying that oestrogen is to your brain what fuel is for an engine. It keeps your brain running.
  2. Endogenous oestrogen (produced within your body) is different from exogenous oestrogen (synthetic). The bioidentical oestradiol is probably the best one to use because it really maps on the same circuits for your own endogenous oestrogen.
  3. I would love for all women to be able to make an informed decision about whether or not hormone therapy is a viable option for them. Many women who are eligible for HRT do not go on HRT out of fear and the fear comes from outdated information, mislabelling on some of the packages.

Follow Dr Lisa on Instagram @dr_mosconi

Click here to find out more about Newson Health

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Jaksot(368)

45 - Inflammation, hormones and the hidden cause of chronic disease

45 - Inflammation, hormones and the hidden cause of chronic disease

In this episode, Dr Louise Newson is joined by Professor Robert Lufkin, physician, medical school professor and author, to explore how inflammation and metabolic dysfunction lie at the heart of many o...

3 Helmi 28min

44 - Testosterone and why the UK is falling behind

44 - Testosterone and why the UK is falling behind

In this episode, Dr Louise Newson is joined by urologist and sexual medicine specialist Prof Mohit Khera to talk about testosterone in women and why it remains one of the most misunderstood and underu...

27 Tammi 29min

43 - Kate Muir on the power and pushback in menopause care

43 - Kate Muir on the power and pushback in menopause care

In this episode, Dr Louise Newson is joined once again by journalist, author and friend Kate Muir to reflect on where the menopause conversation really stands. From the science behind body-identical h...

20 Tammi 30min

42 - Exposing the failures faced by perimenopausal women

42 - Exposing the failures faced by perimenopausal women

In this episode, Dr Louise Newson is joined by Jain monks and filmmakers Sadhvi Siddhali Shree and Sadhvi Anubhuti to discuss their new docuseries, Balance, which follows their personal experiences of...

13 Tammi 38min

41 - How small lifestyle changes can transform your health

41 - How small lifestyle changes can transform your health

In this episode, Dr Louise Newson sits down with GP and lifestyle medicine lead Dr Hussain Al-Zubaidi to talk about the everyday habits that shape long-term health. Hussain shares his own story of bei...

6 Tammi 35min

40 - How hormones reduce inflammation and keep you healthier for longer

40 - How hormones reduce inflammation and keep you healthier for longer

In this episode, Dr Louise Newson speaks with longevity expert and patient advocate Leslie Kenny about health span, inflammation and why prevention matters more than ever.Leslie shares her experience ...

30 Joulu 202531min

39 - Looking back at 2025: progress, pushback and what still needs to change

39 - Looking back at 2025: progress, pushback and what still needs to change

As 2025 comes to a close, Dr Louise Newson reflects on the progress that’s been made this year, as well as the ongoing frustration of knowing too many women are still not being listened to or supporte...

23 Joulu 202524min

38 - Why hormone education matters for every clinician

38 - Why hormone education matters for every clinician

In this episode, Dr Louise Newson and Dr Rebecca Lewis discuss the role of hormone education in modern clinical practice and why so many women are still affected by gaps in training. Drawing on their ...

16 Joulu 202532min

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