#255 - Why you might be a lean mass hyper-responder if you go keto but have high cholesterol | Dave Feldman, Dr. Nick Norwitz & Dr. Dominic D’Agostino

#255 - Why you might be a lean mass hyper-responder if you go keto but have high cholesterol | Dave Feldman, Dr. Nick Norwitz & Dr. Dominic D’Agostino

A lean mass hyper-responder is someone with high LDL and HDL cholesterol and low triglycerides. They are often lean and healthy people who present with strange and alarming lipid numbers after going on the ketogenic diet. Dave Feldman, Dr. Nick Norwitz & Dr. Dominic D’Agostino discuss the LMHR phenotype, whether it’s a concern, whether it’s rare, the Oreo vs statin study, how exercise levels might play a role, and why more research is needed.


Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠⁠⁠https://levels.link/wnl⁠⁠⁠


Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.


🎙 What Dave Feldman, Nick Norwitz, PhD, & Dominic D’Agostino, PhD, discuss:

(4:29) — What is the lean mass hyper-responder phenotype?

(8:32) — Often the LMHR phenotype gets noticed when someone goes low carb

(19:02) — The Oreo cookie study garnered attention for the LMHR phenotype

(25:32) — Understanding the mechanisms of the LMHR

(40:04) — Exercise levels likely play a role in LMHR

(51:26) — The alarming LDL levels in LMHR prompted research

(59:25) — The “gym hypothesis” will be important for further research

(1:10:48) — An open and respectful dialogue is needed on the topic

(1:33:47) — The importance of additional research

⁠⁠Transcripts & Show notes⁠⁠⁠

🔗 Helpful links:

Watch the conversation: https://youtu.be/ItNGrGNvESY

Jaksot(288)

#104 - SEO and the approaches for pursuing a strong organic growth strategy (Ben Grynol, Mike Haney, & Eli Schwartz)

#104 - SEO and the approaches for pursuing a strong organic growth strategy (Ben Grynol, Mike Haney, & Eli Schwartz)

Levels Head of Growth, Ben Grynol, and Levels Editorial Director, Mike Haney, chatted with Growth Advisor and SEO Strategic Consultant, Eli Schwartz. They discussed the idea of SEO as a strategic growth lever and what are the most efficient and inefficient ways of using it. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health. Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health Watch the video – https://youtu.be/UqW-9YsaUpg (07:04) - Prioritize content by user need (10:46) - Don’t overcomplicate SEO (12:33) - Fit SEO into the funnel (17:12) - Focus on search intent (20:41) - Think beyond Google (23:42) - Don’t chase the algorithm (26:55) - SEO isn’t always a great growth lever (29:10) - Put SEO in product, not marketing (31:48) - Engineering-driven SEO is more scalable (42:14) - Don’t do SEO first Transcripts & Show Notes

19 Huhti 202257min

#103 - Starting a New Zealand software company (Dave ten Have & Ben Grynol)

#103 - Starting a New Zealand software company (Dave ten Have & Ben Grynol)

Levels Head of Growth, Ben Grynol, chatted with our Software Engineer, Dave ten Have, about Dave's backstory as a co-founder of Omniblox, how he became an engineer and what he's looking forward to accomplishing in the future.  Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health. Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health (17:15) – Why 3D printing caught Dave’s attention (24:09) – The culture of Silicon Valley (25:39) – The challenges of expectations (31:09) – Focus on your customers (33:18) – Changing the entrepreneurial mindset (34:23) – Startups are like music albums (36:50) – Every health journey is different (37:58) – The narrative of instant success Transcripts & Show Notes

18 Huhti 202249min

#102 - Insulin resistance and how it affects each of us differently (Dr. Ben Bikman & Austin McGuffie)

#102 - Insulin resistance and how it affects each of us differently (Dr. Ben Bikman & Austin McGuffie)

Content creator, Austin McGuffie, AKA Metabolism Mentor, chatted with Levels advisor, Dr. Ben Bikman, about all the different facets of metabolic health including how insulin resistance can affect every person differently based on gender, age and even ethnicity. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health. Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health (05:04) - Keeping insulin low (11:05) - Eating protein first (13:34) - A lesson on fat cell growth (26:14) - The first form of insulin resistance (27:31) - The second form of insulin resistance (29:57) - Elevated insulin causes insulin resistance (31:23) - Lower your insulin intake (36:04) - Type 2 diabetes follows a familial pattern (38:15) - The genetics to get metabolically sick (41:16) - Control carbs, prioritize protein, don't be afraid of fat Transcripts & Show Notes  Watch the video - https://youtu.be/TpH4mUhLFec

15 Huhti 202242min

#101 - How the world is changing the healthcare & prescription process (Varun Boriah & Chris Jones)

#101 - How the world is changing the healthcare & prescription process (Varun Boriah & Chris Jones)

Levels Head of Member Experience, Chris Jones, sat down with SVP and GM of Diagnostics at Truepill, an online B2B pharmacy delivery service. They chatted about supply chain infrastructure for prescriptions as well as how it relates to our Levels ecosystem and the future of the healthcare and prescription process. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health. Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health (03:50) - The future of consumer healthcare (05:40) - Creating a white-label experience (07:13) - Working across a wide spectrum (09:50) - Prioritizing patient confidentiality (12:13) - Consumers are changing healthcare (18:18) - Learning through collaboration (24:10) - Fixing a broken experience (25:07) - The next wave of consumer health (30:07) - From Jupiter to healthcare (44:39) - The consumerization of diagnostics Transcripts & Show Notes  Watch the Video – https://youtu.be/whpMc5jJuM8

13 Huhti 202250min

#100 - Why documentation is important for engineering teams | Maxine Whitely, Steph Coates, Ian Schumann, & Ben Grynol

#100 - Why documentation is important for engineering teams | Maxine Whitely, Steph Coates, Ian Schumann, & Ben Grynol

Creating consistent and cohesive documentation is key for the Levels engineering team. But that’s easier said than done. Ben Grynol talked with some of our software engineers, Maxine Whitely, Steph Coates, and Ian Schumann, to break down their approach to documentation. They talked about why it matters for an asynchronous remote team, how it mirrors building healthy habits, and why it’s worth it to invest in documentation now for everyone on the team as well as how it will benefit future engineers as we scale. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health. Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health 🎙️ What they discuss: (02:54) - The parable of the engineer (05:03) - A bridge to non-technical stakeholders (09:30) - Having the time to document (10:12) - Understanding through teaching (13:06) - A culture of documentation (20:00) - Avoid documentation debt (20:34) - Pay now or pay later (23:49) - Don’t make assumptions (26:10) - Bottlenecks without documentation (37:47) - Curate your work for your team Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health. Look for multiple new shows per week on Levels - A Whole New Level, where we have in-depth conversations about how the Levels startup team builds a movement from the ground up in the health and wellness tech industry. ⁠Transcript & show notes⁠ 🔗 Helpful links: Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1

11 Huhti 202253min

#99 - How to make a real impact in the community: Opportunities & challenges | Mac Conwell & Ben Grynol

#99 - How to make a real impact in the community: Opportunities & challenges | Mac Conwell & Ben Grynol

It can be a challenge to reach the communities you want to impact most. How do you know you’re taking the right steps and making the right connections? The good news is it doesn’t have to happen overnight or with one big initiative; you just have to work consistently with the communities. In this episode, Ben Grynol talked with one of our investors and Co-Founder of RareBreed Ventures, McKeever “Mac” Conwell. They chatted about the idea of reaching communities that are most impacted by poor metabolic health and what we can do collectively as a society to ensure we’re taking the right steps to reach them, as well as the opportunities, challenges, and initiatives for making meaningful change in the community. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health. Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health 🎙 What Mac Conwell & Ben Grynol discuss: (15:08) – Looking for opportunity (18:37) – Inform your community (23:50) – Change has to come from both ends (25:11) – Reimagine how people interact with products (30:06) – Startups break the rules (37:19) – Bring in creative people (41:44) – Create open access to jobs (44:56) – Share resources with community leaders (49:00) – Widening the net Transcripts and Show Notes 🔗 Helpful links: Watch the conversation: https://youtube.com/watch?v=wSV23rItORI&feature=youtu.be Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1

8 Huhti 202251min

#98 - Changing your mindset to "maybe" (Ben Grynol & Mike DiDonato)

#98 - Changing your mindset to "maybe" (Ben Grynol & Mike DiDonato)

Levels Head of Growth, Ben Grynol, sat down with Head of Success, Mike DiDonato. They deconstructed the idea about mindset and how it relates to some of the situations Mike has faced over the past month. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health. Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health (23:09) – You have to keep going (24:04) – Try to be still (24:53) – There’s always more to learn (29:20) – Resentment is distracting (31:08) – You are what you think about (35:02) – You’re responsible for your response (38:09) – Be the best version of yourself (39:49) – How to keep going (41:43) – Minimize your regrets (50:24) – Don’t project your expectations onto others Transcripts and Show Notes

6 Huhti 202256min

#97 - How environmental chemicals are making us sick and fat (Dr. Rob Lustig & Dr. Casey Means)

#97 - How environmental chemicals are making us sick and fat (Dr. Rob Lustig & Dr. Casey Means)

Landmark new research published by Dr. Rob Lustig and dozens of other scientists shows us for the first time the intricate mechanisms of how environmental chemicals directly cause obesity, uncovering the latest research on this class of chemicals called obesogens. In this conversation between Dr. Rob Lustig and Dr. Casey Means, they discuss what products and environmental toxins we need to be aware of, how they are impacting our cells and causing metabolic dysfunction, and what we can do to protect ourselves.  Dr. Lustig speaks to how these environmental toxins affect our sex cells (sperm and eggs) and can impact our offspring and many generations to come. He also discusses how 15% of obesity may be directly caused by these chemicals.  Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health. Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health (07:58) - It’s not just correlative, it’s causative (10:51) - Obesogens bind to our cell proteins (11:27) - Everyday products contain obesogens (14:37) - Babies and children are the most vulnerable (24:34) - Obesogens stick around even after being banned (32:19) - Food is more than calories (43:05) - Obesogens are unregulated (51:05) - Cell alterations last for generations (01:54:00) - We need to get the EPA on board (01:02:15) - Buy organic Transcripts and Show Notes Watch the Video – https://youtu.be/GQrnEx8MNKk

5 Huhti 20221h 13min

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