#172: Dom D'Agostino -- The Power of the Ketogenic Diet

#172: Dom D'Agostino -- The Power of the Ketogenic Diet

Dr. Dominic "Dom" D'Agostino (@DominicDAgosti2) is an assistant professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine, and a senior research scientist at the Institute for Human and Machine Cognition (IHMC). He has also deadlifted 500 pounds for 10 reps after a seven-day fast. Many of you sent enthusiastic follow-up questions after the last conversation we had, so Dom took the time to answer your most popular questions. In particular, he focused on ketosis, ketones, and the ketogenic diet -- so you can consider it the ketosis master class (especially if you combine both episodes, though this one does stand alone). It takes a few minutes for Dom to warm up -- so be patient! If you have an interest in these types of metabolic therapies, whether for performance enhancement, endurance, weight loss, or fighting cancer, diabetes, or any number of other maladies, you will find a gem within this episode. Enjoy! Show notes and links for this episode can be found at www.fourhourworkweek.com/podcast. This podcast is brought to you Gymnastic Bodies. This is the training system that I am most obsessed with at the moment. Coach Sommer appeared on a previous episode of the podcast, which turned into a sleeper hit. He is the former USA national team coach for men's gymnastics and creator of this bodyweight-based training system. I'm not easily impressed, and I have been completely blown away by the sophistication and the elegance of his programming. I have been using Gymnastic Bodies for just a few months now, and I already feel more flexible and stronger than I have in years. Check out GymnasticBodies.com/tim, where you'll find the Fundamentals course for diagnosing your weakest areas, those you can tweak for fast improvements. It is incredible. Take a look at GymnasticBodies.com/tim for more details and a large discount. This podcast is also brought to you by Four Sigmatic. I reached out to these Finnish entrepreneurs after a very talented acrobat introduced me to one of their products, which blew my mind (in the best way possible). It is mushroom coffee featuring chaga, which was introduced to me by Laird Hamilton, the king of big wave surfing. You just add the entire packet to hot water. It tastes like coffee, but there are only 40 milligrams of caffeine, so it's got less than half of what you would find in a regular cup of coffee. I do not get any jitters, acid reflux, or any type of stomach burn. It put me on fire for an entire day, and I only had half of the packet! People are always asking me what I use for cognitive enhancement -- right now, this is the answer. You can try it right now by going to foursigmatic.com/tim and using the code "Tim" to get 20 percent off your first order. If you are in the experimental mindset, I do not think you'll be disappointed.

***

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#865: The Most Incredible Transformation I’ve Ever Seen — Jerzy Gregorek on Autism, Cerebral Palsy, Coaching, and the Power of Micro-Progressions

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Jerzy Gregorek (@TheHappyBody) is a 4x World Weightlifting Champion, co-founder of UCLA’s weightlifting team, and co-creator, with his wife Aniela, of the Happy Body program. You can watch the documen...

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#864: How to Simplify Your Life in 2026 — New Tips from Anne Lamott, Claire Hughes Johnson, David Yarrow, and Diana Chapman

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#862: Cathy Lanier, Chief Security Officer of the NFL — From 9th-Grade Dropout to DC's Longest-Serving Police Chief, Protecting the Super Bowl, and Resilience Under Extreme Pressure

#862: Cathy Lanier, Chief Security Officer of the NFL — From 9th-Grade Dropout to DC's Longest-Serving Police Chief, Protecting the Super Bowl, and Resilience Under Extreme Pressure

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23 Huhti 1h 35min

#861: 4-Hour Workweek Success Story Brian Dean — From Dad’s Basement to Selling Two Companies

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Brian Dean is the founder of Backlinko and Exploding Topics, both acquired by Semrush, which itself was recently acquired by Adobe for $1.9 billion. Brian's story starts exactly where a lot of great s...

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#860: Daredevil Michelle Khare — How to Become a YouTube Superstar, Open Impossible Doors (FBI, Secret Service, etc.), Craft Jedi-Level Cold Emails, and Use Fear-Setting to Change Your Life

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#859: Q&A with Tim — The Upcoming AI Tsunami and Building Offline Advantage, Book Recommendations, Spotting Psychedelic Red Flags, Courage as a Learnable Skill, and More

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Welcome back to another in-between-isode, with one of my favorite formats: the good old-fashioned Q&A.This episode is brought to you by:Our Place’s Titanium Always Pan® Pro using nonstick technology t...

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