#117: Dom D'Agostino on Fasting, Ketosis, and The End of Cancer

#117: Dom D'Agostino on Fasting, Ketosis, and The End of Cancer

Dr. Dominic “Dom" D’Agostino (@DominicDAgosti2) is an Assistant Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine, and a Senior Research Scientist at the Institute for Human and Machine Cognition (IHMC). He has also deadlifted 500 pounds for 10 reps after a seven-day fast. He’s a beast and — no big surprise — he’s a good buddy of Dr. Peter Attia, my MD friend who drinks "jet fuel" in search of optimal athletic performance. The primary focus of Dom's laboratory is developing and testing metabolic therapies, including ketogenic diets, ketone esters and ketone supplements to induce nutritional/therapeutic ketosis. D’Agostino’s laboratory uses in vivo and in vitro techniques to understand the physiological, cellular and molecular mechanism of metabolic therapies and nutritional strategies for peak performance and resilience. His research is supported by the Office of Naval Research (ONR), Department of Defense (DoD), private organizations and foundations. Show notes and links for this episode can be found at www.fourhourworkweek.com/podcast. This podcast is brought to you by Audible. I have used Audible for years and I love audio books. I have 2 to recommend: The Graveyard Book by Niel Gaiman Vagabonding by Rolf Potts All you need to do to get your free audiobook and a free 30-day trial is go to Audible.com/tim. Choose one of the above books, or choose between more than 180,000 audio programs. That could be a book, a newspaper, a magazine or even a class. It's that easy. Go to Audible.com/Tim and get started today. Enjoy! This podcast is also brought to you by 99Designs, the world’s largest marketplace of graphic designers. I have used them for years to create some amazing designs. When your business needs a logo, website design, business card, or anything you can imagine, check out 99Designs. I used them to rapid prototype the cover for The 4-Hour Body, and I've also had them help with display advertising and illustrations. If you want a more personalized approach, I recommend their 1-on-1 service, which is non-spec. You get original designs from designers around the world. The best part? You provide your feedback, and then you end up with a product that you're happy with or your money back. Click this link and get a free $99 upgrade. Give it a test run… Enjoy!

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#823: Dr. Jeffrey Goldberg — Creating Supranormal Vision, Cutting-Edge Science for Eye Health, Supplements, Red Light Therapy, and The Future of Eyesight Restoration

#823: Dr. Jeffrey Goldberg — Creating Supranormal Vision, Cutting-Edge Science for Eye Health, Supplements, Red Light Therapy, and The Future of Eyesight Restoration

Dr. Jeffrey Goldberg is Professor and Chair of Ophthalmology and Director of the Byers Eye Institute at Stanford University, a leading scientist in the development and degeneration of the visual syste...

20 Elo 20251h 44min

#822: The Random Show — Ketones for Cognition, Tim’s Best Lab Results in 10+ Years, How Kevin Hit 100 Days Sober, Home Defense, Vibe Coding Unleashed, and More

#822: The Random Show — Ketones for Cognition, Tim’s Best Lab Results in 10+ Years, How Kevin Hit 100 Days Sober, Home Defense, Vibe Coding Unleashed, and More

Welcome to another wide-ranging "Random Show" episode that I recorded with my close friend Kevin Rose (digg.com)! We cover Kevin's sobriety journey and marking 100 days without alcohol, my results wit...

13 Elo 20252h 7min

#821: My Two-Year Secret Project, COYOTE — The Strategies and Tactics for Building a Bestseller from Nothing with Elan Lee of Exploding Kittens

#821: My Two-Year Secret Project, COYOTE — The Strategies and Tactics for Building a Bestseller from Nothing with Elan Lee of Exploding Kittens

This is a very special episode for me. My brand-new card game, COYOTE, created in collaboration with Elan Lee and Exploding Kittens, is here. It is available in ~8,000 locations worldwide, including W...

6 Elo 20253h

#820: Elizabeth Gilbert — How to Find Your Inner Voice, Set Strong Boundaries, and Live a Life of Radical Ease (Repost)

#820: Elizabeth Gilbert — How to Find Your Inner Voice, Set Strong Boundaries, and Live a Life of Radical Ease (Repost)

Elizabeth Gilbert is the #1 New York Times bestselling author of Big Magic and Eat, Pray, Love as well as several other international bestsellers. Her latest novel, City of Girls, was named an instant...

30 Heinä 20251h 56min

#819: Rhonda Patrick, Ph.D. — Protocols for Fasting, Lowering Dementia Risk, Reversing Heart Aging, Using Sauna for Longevity (Hotter is Not Better), and a Few Supplements That Might Actually Matter

#819: Rhonda Patrick, Ph.D. — Protocols for Fasting, Lowering Dementia Risk, Reversing Heart Aging, Using Sauna for Longevity (Hotter is Not Better), and a Few Supplements That Might Actually Matter

Rhonda Patrick, Ph.D. (@foundmyfitness) is a biomedical scientist and the founder of FoundMyFitness, a platform dedicated to delivering rigorous, evidence-based insights on improving healthspan and mi...

23 Heinä 20252h 31min

#818: John Arnold with Dr. Peter Attia — The Greatest Energy Trader of All Time on Lessons Learned, Walking Away from Wall Street, and Reinventing Philanthropy

#818: John Arnold with Dr. Peter Attia — The Greatest Energy Trader of All Time on Lessons Learned, Walking Away from Wall Street, and Reinventing Philanthropy

In this special episode, my friend—and fan-favorite guest—Dr. Peter Attia takes the mic as guest host. Peter sits down with legendary trader John Arnold, widely considered the greatest energy trader o...

1 Heinä 20252h 36min

#817: 4-Hour Workweek Success Stories — Charlie Houpert on Building “Charisma on Command” to 10M+ Subscribers, From Charging $10 for Seminars to Making Millions, Living in Brazil, Critical Early Decisions, and The Secret to Freedom

#817: 4-Hour Workweek Success Stories — Charlie Houpert on Building “Charisma on Command” to 10M+ Subscribers, From Charging $10 for Seminars to Making Millions, Living in Brazil, Critical Early Decisions, and The Secret to Freedom

Charlie Houpert is the co-founder of Charisma on Command, a company that helps people develop confidence, charisma, and strong social skills. Originally launched as a 4-Hour Workweek-inspired “muse,” ...

25 Kesä 20252h 14min

#816: Nsima Inyang, Mutant and Movement Coach — True Athleticism at Any Age, Microdosing Movement, “Rope Flow” as a Key Unlock, Why Sleds and Sandbags Matter, and Much More

#816: Nsima Inyang, Mutant and Movement Coach — True Athleticism at Any Age, Microdosing Movement, “Rope Flow” as a Key Unlock, Why Sleds and Sandbags Matter, and Much More

Nsima Inyang (@nsimainyang) is a strength athlete, movement coach, and co-host of Mark Bell’s Power Project, one of the top fitness podcasts in the world. He is also one of the most freakishly athleti...

18 Kesä 20253h 18min

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