Alzheimer’s Can Be Prevented & Reversed: Drs. Dean & Ayesha Sherzai On Optimizing Brain Health
The Rich Roll Podcast27 Marras 2017

Alzheimer’s Can Be Prevented & Reversed: Drs. Dean & Ayesha Sherzai On Optimizing Brain Health

While other major diseases are in decline, deaths from Alzheimer's have increased dramatically in recent decades. In fact, Alzheimer's is currently the 6th (and due to massive under-reporting may be as high as the 3rd ) leading cause of death in the United States. Right now, over 47 million people worldwide currently live with Alzheimer's. By 2050, it's predicted this form of dementia will plague 135.5 million people across the globe. This disease has become so pervasive, chances are you have been directly or indirectly impacted through an afflicted loved one. If so, then you know first hand the devastation it creates. You've seen it's ravaging effects. Perhaps you've even shouldered the immense emotional, financial and social burden it produces — and the hopelessness it provokes. The sad truth is that Alzheimer's is a condition that Western medicine has utterly failed to combat, let alone cure. Simply put, there is no pharmaceutical or surgical treatment to effectively prevent or reverse this savage and cataclysmic condition. But there is hope. Alzheimer's isn't a genetic inevitability. A diagnosis doesn't have to come with a death sentence. In fact, according to this week's guests, 90% of all Alzheimer's cases can be prevented. And for the 10% with a strong genetic risk for cognitive decline, the disease can be delayed for ten to fifteen years. These are not estimates. Nor are they wishful thinking. They are conclusions based on rigorous science performed by neurologists Drs. Dean and Ayesha Sherzai. Co-directors of the Brain Health and Alzheimer's Prevention Program at Loma Linda University Medical Center, Team Sherzai is the dynamic husband and wife duo behind the largest clinical and observational study on Alzheimer's to date as well as the co-authors of The Alzheimer's Solution*, a must-read primer that details their extensive research, chronicles the remarkable results they have experienced working with patients first-hand, and sets forth the first ever comprehensive program to prevent Alzheimer's disease, improve cognitive function, and ultimately optimize long-term brain health. The solution might surprise you. It's not due to a breakthrough in surgical procedures. It's not the result of new pharmaceutical trials. Instead, as far fetched as it may sound, the answer is rooted in fundamental, simple changes in nutrition and lifestyle. Dr. Dean Sherzai, M.D., PhD., completed his medical and neurology residencies at Georgetown University with a subsequent fellowship in neurodegenerative diseases at the National Institutes of Health, followed by a second fellowship in Dementia and Geriatrics at the University of California, San Diego. He also holds two Masters Degrees; in advanced sciences at UCSD and a Masters in public health from Loma Linda University. Finally, he has received a Ph.D. in Healthcare leadership at Loma Linda/Andrews University. Dr. Ayesha Sherzai, M.D., completed her medical residency at Loma Linda University. She subsequently completed a residency in preventive medicine and neurology and thereafter received a fellowship in vascular neurology from Columbia University, and is currently finalizing her PhD in Epidemiology at Loma Linda University. Ayesha also has a culinary degree, giving her a unique understanding of nutrition as a powerful tool for disease prevention. Peace + Plants, Rich

Jaksot(959)

Heidi Zuckerman: Why Art Matters

Heidi Zuckerman: Why Art Matters

What defines art? What makes one an artist? What does art teach us—and why does it matter? To help us make sense of a world elusive to many, today I convene with the singular Heidi Zuckerman. A woman I’ve known for over 30 years, Heidi has devoted her entire professional career to understanding art, the people who make art, and why we should care. Heidi currently serves as CEO and Director of the Orange County Museum of Art, where she is overseeing construction of a spectacular new building designed by legendary architect Thom Mayne of Morphosis, scheduled to open in October 2022. In addition, she hosts Conversations About Art (a podcast on which I was privileged to be a guest) and is the author of the Conversations with Artists book series. This is a conversation about art. In addition to tracking Heidi’s career arc, we discuss what defines art, what makes for great art, why we should care about art, and why artists matter. We discuss the barriers to accessing art. How art can and should be democratized. And the role of art and artists in this era of offense and content overload. On a personal level, this one is very meaningful given my long history with Heidi. I really enjoyed this conversation—I hope you learn as much as I did. Watch: YouTube. Read: Show notes Peace + Plants, Rich

8 Elo 20221h 55min

Peter Attia, MD On Becoming a Centenarian Decathlete, Metabolic Health & All Things Zone 2

Peter Attia, MD On Becoming a Centenarian Decathlete, Metabolic Health & All Things Zone 2

Healthspan extension may pique your interest. But it’s the obsession of today’s guest, a physician and engineer focused on the applied science of longevity to reframe and improve how we live while challenging all we’ve been previously taught about the interaction of health, human performance, and medicine. Meet Peter Attia, MD. Peter’s current practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (how long you live), while simultaneously improving healthspan (the quality of your life). Today’s conversation, the first in what I hope to be many, focuses on the following specific topics: Longevity. From a holistic perspective, discussing the physical, mental and emotional pillars required to erect the foundation for a long life well-lived, including how and why he is training (as all us of should be) for what he calls “The Centenarian Decathlon”. Metabolic health. What this actually means, how to optimize it, and the role a Continuous Glucose Monitor (or CGM) can play in engaging you with your own metabolic health. Strength, mobility and brain health. Zone 2 training. What it is, how to do it, and why it’s important. Peter is an utterly fascinating human with a clear grasp of science and how to effectively communicate it. I hope you enjoy this exchange as much as I was honored to host it. Watch: YouTube. Read: Show notes Peace + Plants, Rich

1 Elo 20222h 20min

Colin O’Brady & Jenna Besaw On Possible Mindsets, K2 Perils & 12-Hours Walks

Colin O’Brady & Jenna Besaw On Possible Mindsets, K2 Perils & 12-Hours Walks

World-record setting adventure athlete and New York Times bestselling author Colin O’Brady returns for his fifth appearance on the podcast (RRP 207, 235, 439 & 519), this time alongside wife and partner in all things Jenna Besaw —the powerful engine behind everything they have accomplished together. Today we discuss what global exploration has taught Colin & Jenna about mindset. We talk about the transformative power of an all-day walk, the subject of Colin's new book, 'The 12-Hour Walk'. Packed with actionable takeaways ad incredible stories, this is a long one, but I implore you to stick around for the final hour— a harrowing first-person account of the trauma and tragedy of death on K2. Watch: YouTube. Read: Show notes Peace + Plants, Rich

25 Heinä 20223h 20min

Roll On: Everything Roll On

Roll On: Everything Roll On

After a brief hiatus, the boys are back with a classic "old school" edition of 'Roll On', the version of the podcast where we ramble on matters of interest across culture, sports, art, politics, self-betterment, and more. This might be the most Roll On Roll On of all Roll Ons. As always, my co-host is Mr. Adam Skolnick, an activist, veteran journalist, and David Goggins’ Can’t Hurt Me co-author. Specific topics discussed in today’s episode include: Rich’s recent adventures in Colorado (and getting COVID—again); how Jim Thorpe was finally restored as sole winner of 1912 Olympics; Kaitlin Armstrong’s capture in Costa Rica; Francois D’Haene, Kilian Jornet & Courtney Dauwalter’s impressive Hardrock 100 results; Yoshihiko Ishikawa stunning performance at the Badwater 135; the importance of the Webb Telescope images; and  women’s healthcare rights and the future of abortion in America. In addition, we answer the following listener questions: Is an unbalanced life centered on work a rite of passage when it comes to success? How do you embody gratitude? What books changed your life? If you want your query discussed, drop it on our Facebook Page, or better yet leave a voicemail at (424) 235-4626. Today’s episode is also viewable on YouTube. Show notes:+ MORE: https://bit.ly/richroll693 Peace + Plants, Rich

21 Heinä 20222h 13min

Malcolm Gladwell Is Lord Of All Things Overlooked and Misunderstood

Malcolm Gladwell Is Lord Of All Things Overlooked and Misunderstood

What are the limits of human performance? How can we reimagine sport to boost lifelong adoption? And what is the athlete’s role in moving culture forward? Today we explore these questions and tons more with the lord of all things overlooked and misunderstood, Malcolm Gladwell. I suspect most of you are very familiar with Malcolm. Perhaps you’ve listened to his sensational podcast Revisionist History, where every episode re-examines something from the past—an event, a person, an idea, even a song—and asks whether our collective stories got it right the first time. Or maybe you’ve read one of his six New York Times best sellers, such as The Tipping Point,Blink, Outliers, David and Goliath, and Talking to Strangers. Today’s conversation begins with running, extends to sport, broadens into a conversation about the role of athletes in moving society forward, and (of course) unearths other topics overlooked and misunderstood—all in true Gladwellian style. We talk about his latest podcast, Legacy of Speed, and why this terrain just might be his most Gladwellian project to date. Malcolm also shares several of his orthogonal ideas around education, publishing, the future of audio, creativity, and many more fascinating topics. Today’s episode is also viewable on YouTube. More about Malcom + show notes: https://bit.ly/richroll692a Malcolm is someone I’ve wanted on the show since day one, and I am thrilled to finally have made it happen. I hope you enjoy this exchange as much as I was thrilled to host it. Peace + Plants, Rich

18 Heinä 20221h 59min

Robin Arzón On Turning Doubt Into Determination & Plateaus Into Launching Pads

Robin Arzón On Turning Doubt Into Determination & Plateaus Into Launching Pads

Robin Arzón -- the inspiring and highly energetic self-proclaimed ambassador of sweat and swagger is back for her fourth appearance on the podcast. A former corporate lawyer with degrees from NYU and Villanova Law, Robin transformed herself into a global fitness icon and everybody’s favorite Peloton instructor—the company where she also holds the title of Vice President of Fitness Programming and Head Instructor. In 2020 Robin was named one of the most influential people on Fortune Magazine’s 40 Under 40 list. Robin is also a two-time New York Times bestseller of Shut Up And Run, and her latest book, Strong Mama. Finally, she recently launched a Master Class on all things mental strength. Today’s episode is also viewable on YouTube. More about Robin + show notes: https://bit.ly/richroll691 I adore Robin. She never fails to ignite the best in us all. If this conversation leaves you inspired, there is more where that came from in RRP #99, RRP #137 & RRP #230. Peace + Plants, Rich

11 Heinä 20221h 41min

Valter Longo PhD: Fasting & Nutrition Protocols for Longevity & Disease Prevention

Valter Longo PhD: Fasting & Nutrition Protocols for Longevity & Disease Prevention

When it comes to fasting, how do you parse fact from fiction? How do nutrition and lifestyle choices make or break disease? And how do we eat to live longer, healthier lives? To help us answer these questions, Dr.Valter Longo is back. Dr. Longo first graced the show back on RRP #367, where we covered the basics for fasting for longevity. Today we are getting granular on the science of longevity & nutrition, including an analysis of the latest research on fasting and what Dr. Longo calls the fasting-mimicking diet and its connection to healthspan extension & disease prvention, So today we pick up where we left off four years ago, covering: The latest research on fasting and his fasting-mimicking diet; the 5 nutrition pillars of longevity and various fasting strategies, optimal protein intake based on age, high fat versus low-fat diets, and how to think about and contextualize continuous glucose monitoring; the science around rapamycin, metformin and sirtuins; and many other topics. Today’s episode is also viewable on YouTube. Learn more + show notes: https://bit.ly/richroll690 Valter is one of the world’s brightest minds on the cutting edge of longevity science and this one is full of prescriptive advice. I hope you learn as much as I did. Peace + Plants, Rich

4 Heinä 20221h 55min

Camille Herron: Crushing World Records, Narrowing The Gender Gap, And The Power of Happiness

Camille Herron: Crushing World Records, Narrowing The Gender Gap, And The Power of Happiness

She collects world records with wild abandon. With each race, she narrows the gender gap, rewriting the rulebook on human capability with a broad smile and arms outstretched. Meet force of nature Camille Herron. Alongside 21 marathon victories, Camille won the Comrades Marathon in 2017, becoming the first athlete to win World Championship titles in the 50K, 100K and clocking the most miles in 24 hours (167.8 to be specific) of any woman in history. Just after turning 40, earlier this year Camille took home a big win at the Jackpot 100, beating all the men and besting her own 100-mile Road World Record. In addition, Camille is the youngest woman to reach 100,000-lifetime running miles and she holds my favorite world record—fastest marathon in a superhero costume—running 2:48 dressed head to toe as Spiderwoman. Today she shares her unique story, in her own unique way. How can a woman who commits herself to such hellish feats of physical performance remain so joyous? Today we dissect it all: Camille’s relentless positivity, her unique backstory, her unique, quality over quantity training style, how she thinks about closing the gender gap in ultra running, the importance of strength training, how blood work has impacted her focus on nutrition, the difference between trail running and road running, her near term goals and future ambitions. We also talk about how she manages being married to her coach Conor Holt, how running can be self-transcendent, and many other interesting topics. More about Camille + show notes: https://bit.ly/richroll689 Today’s episode is also viewable on YouTube: https://bit.ly/camilleherron689a Camille is an unbridled optimist, a super fun hang, and an inspiration for all—especially for those of us pondering our athletic capabilities as we age up. Peace + Plants, Rich

27 Kesä 20221h 55min

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