David Sinclair On Extending Human Lifespan & The Science Behind Aging

David Sinclair On Extending Human Lifespan & The Science Behind Aging

Everybody grows old. Everyone dies. But is this scientific fact? Or is it merely a story based on history and our current understanding of biology? What if we instead consider aging as a disease? This begs the question: what is the cure? Welcome to the mind of David Sinclair, PhD, one of the world’s leading scientific authorities on longevity, aging and how to slow its effects. A professor in the Department of Genetics at Harvard Medical School and co-Director of the Paul F. Glenn Center for the Biological Mechanisms of Aging, David obtained his Ph.D. in Molecular Genetics at the University of New South Wales, Sydney in 1995 and worked as a postdoctoral researcher at M.I.T. where, among other things, he co-discovered the cause of aging for yeast. The co-founder of several biotechnology companies, David is also co-founder and co-chief editor of the journal Aging. His work has been featured in a variety of books, documentaries, and media, including 60 Minutes, Nightline and NOVA. He is an inventor on 35 patents, has been lauded as one of the Top 100 Australian Innovators, and made TIME magazine’s list of the 100 most influential people in the world. In addition, David is the author of the forthcoming book, Lifespan: The Revolutionary Science of Why We Age — and Why We Don't Have To* which hits bookstores on Sept. 10 and is currently available for pre-order here*. This is an absolutely fascinating conversation on all things human lifespan, aging and longevity. We begin with the specific scientific mechanisms that contribute to biological degeneration. Then we dive deep into the hard science David and his peers are examining to better understand what contributes to aging and how to prevent it. According to David, the prospect of living to 200+ is not a pipe dream, but a very possible reality. If humans could indeed double lifespan, how would this change how you live? And what does this mean for the future of humanity? This conversation travels deep into the scientific weeds. Perfect for the geeks among us. But it's also grounded in practical takeaways for all of us — because David's work isn't just about extending lifespan. It's about learning how to live as vibrantly and energetically as possible for as long as possible. It’s an honor and a privilege this brilliant man’s pioneering work and wisdom with you today. Plus he's a lovely guy. If you enjoyed my episode with Dr. Valter Longo (RRP #367), a fellow brilliant warrior in the longevity space, then I’m fairly confident you’re going to love this one. So break out that pen and paper, because you're going to want to take notes on this one. I sincerely hope you enjoy the episode. Peace + Plants, Rich

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Phil Stutz & Elise Loehnen Share Tools For Inner Well-being, How To Embrace Pain, Uncertainty & Constant Work As Divine Invitations, & Why Everything You’re Avoiding Will Transform Your Life

Phil Stutz & Elise Loehnen Share Tools For Inner Well-being, How To Embrace Pain, Uncertainty & Constant Work As Divine Invitations, & Why Everything You’re Avoiding Will Transform Your Life

Phil Stutz is the legendary psychiatrist, author, and protagonist in the Netflix documentary “Stutz.” Alongside co-author and writer Elise Loehnen, they explore their new book “True & False Magic.”   This conversation delves into “Part X”—the destructive force within us all—along with Universe 1 vs. Universe 2 thinking, and how pain, uncertainty, and constant work serve as unavoidable portals to growth. Together, they present actionable tools and a profound spiritual framework for living fully.   Along the way, Phil illustrates concepts with hand-drawn diagrams, while Elise translates these insights into everyday practice.    Their complementary wisdom offers a rare treasure—an invitation to a more expansive way of being. Enjoy!   Show notes + MORE Watch on YouTube Newsletter Sign-Up   Today’s Sponsors: iFit: Use the code RICHROLL to get 10% off any purchase of $999+ 👉NordicTrack.com/richroll On: High-performance shoes & apparel crafted for comfort and style 👉on.com/richroll  Bon Charge: Get 15% OFF all my favorite wellness products w/ code RICHROLL 👉 boncharge.com                  AG1: Get a FREE bottle of Vitamin D3+K2 AND 5 free AG1 Travel Packs 👉drinkAG1.com/richroll         Squarespace: Use the code RichRoll to save 10% off your first purchase of a website or domain 👉Squarespace.com/RichRoll   BetterHelp: Get 10% OFF the first month👉BetterHelp.com/richroll                            Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors   Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

14 Huhti 1h 29min

Power, Property, & Prestige: Kurt Sutter & Katey Sagal Share The Unfiltered Truth About Marriage, Recovery, Success Addiction & The Path Back To Purpose

Power, Property, & Prestige: Kurt Sutter & Katey Sagal Share The Unfiltered Truth About Marriage, Recovery, Success Addiction & The Path Back To Purpose

Kurt Sutter and Katey Sagal are the Hollywood power couple behind “Sons of Anarchy,” numerous iconic performances, and hosts of the podcast “PIE.”   This conversation strips bare the intoxicating trap of fame, the parallel paths that led them both to sobriety at 31, and the brutal honesty required to save their relationship when “money, property, and prestige” threatened everything.   Kurt’s evolution from Hollywood’s combative bad boy to spiritual seeker alongside Katey’s unflinching wisdom on intimacy creates a masterclass in reinvention.    They’re authentic. They’re vulnerable. Their journey might change how you think about success. Enjoy!   Show notes + MORE Watch on YouTube Newsletter Sign-Up  Today’s Sponsors: Momentous: 20% OFF all of my favorite products  👉livemomentous.com/richroll  Roka: Unlock 20% OFF your order with code RICHROLL 👉ROKA.com/RICHROLL Pique: Get up to 20% OFF plus a FREE rechargeable frother and glass beaker with your first purchase 👉piquelife.com/richroll OneSkin: Get started today with 15% off using code RICHROLL at oneskin.co  LMNT: Get a free LMNT Sample Pack with any purchase 👉 drinkLMNT.com/richroll     Bragg: Get 20% OFF your first order with code RICHROLL👉 Bragg.com                                    IQBAR: Get 20% OFF all IQBAR products plus FREE shipping. Just text RICHROLL to sixty-four thousand. Message and data rates may apply.             Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors   Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

10 Huhti 2h 3min

Let Them Theory: Mel Robbins On Reclaiming Your Power, Finding Freedom In Letting Go & The Simple Tool That's Transforming Millions of Lives

Let Them Theory: Mel Robbins On Reclaiming Your Power, Finding Freedom In Letting Go & The Simple Tool That's Transforming Millions of Lives

Mel Robbins is a celebrated podcast host, #1 New York Times bestselling author, and one of the most sought-after experts in mindset and behavior change.   This conversation explores the paradox at the heart of human suffering—that we exhaust ourselves trying to control the uncontrollable. Mel’s counterintuitive “Let Them Theory” offers a deceptively simple yet profound antidote to this universal struggle, challenging us to disabuse ourselves of the illusion of control and redirect our energy toward what truly matters.   She deftly unpacks how relinquishing the compulsion to manage others ultimately grants us the equanimity we’ve all been seeking.   Mel is a beacon—and this conversation is a path to personal liberation. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today’s Sponsors: Bon Charge: Get 15% OFF all my favorite wellness products w/ code RICHROLL 👉 boncharge.com                                                                                                                           Squarespace: Use the code RichRoll to save 10% off your first purchase of a website or domain 👉Squarespace.com/RichRoll                                                                                                       Airbnb: Your home might be worth more than you think. Find out how much at 👉 airbnb.com/host  AG1: Get a FREE bottle of Vitamin D3+K2 AND 5 free AG1 Travel Packs 👉www.drinkAG1.com/richroll            Go Brewing: Use the code Rich Roll for 15% OFF 👉gobrewing.com           Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors   Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

7 Huhti 1h 50min

You Are Already Enough: Maria Shriver On Finding Your Voice, Healing After Heartbreak, Brain Health Advocacy, & The Power Of Self-Acceptance

You Are Already Enough: Maria Shriver On Finding Your Voice, Healing After Heartbreak, Brain Health Advocacy, & The Power Of Self-Acceptance

Maria Shriver is a renowned journalist, Kennedy family scion, and award-winning advocate for women's brain health. This conversation explores the parasocial relationship between public figure and audience as Maria shares her authentic journey of self-discovery through poetry. We discuss her upbringing in America's political "royalty," the transactional nature of achievement-based love, finding wholeness after heartbreak, and her groundbreaking work in Alzheimer's research. She shares profound insights on disentangling our true selves from predetermined narratives and the magnanimous act of forgiveness. Maria’s courage is undeniable. This conversation might just change how you see yourself. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today’s Sponsors: Momentous: 20% OFF all of my favorite products 👉livemomentous.com/richroll Go Brewing: Use the code Rich Roll for 15% OFF 👉gobrewing.com BetterHelp: Get 10% OFF the first month 👉BetterHelp.com/richroll. Prolon/L-Nutra: Get 15% OFF plus a FREE bonus gift 👉prolonlife.com/richroll Bon Charge: Get 15% OFF all my favorite wellness products w/ code RICHROLL 👉boncharge.com Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

31 Maalis 1h 49min

ROLL ON 2025 So Far: Navigating Uncertainty, Getting Unstuck, Elmo, Psychedelics, ‘Adolescence’ & More

ROLL ON 2025 So Far: Navigating Uncertainty, Getting Unstuck, Elmo, Psychedelics, ‘Adolescence’ & More

Roll On is back baby! Today Rich and Adam Skolnick catch up on the decade that is 2025. On tap is SXSW, Elmo, psychedelics, the LA fires, and practical strategies for navigating the turbulence of our current moment. They also go deep on the Netflix hit “Adolescence” and its many important themes, including the impact of social media on teenagers and the crisis of young men. Along the way, they answer listener questions and more. Rejoice! Show notes + MORE  Watch on YouTube Newsletter Sign-Up   Today’s Sponsors: Seed: Use code RICHROLL25 for 25% OFF your first order 👉seed.com/RichRoll Go Brewing: Use the code Rich Roll for 15% OFF 👉gobrewing.com Pique: Get up to 20% OFF plus a FREE rechargeable frother and glass beaker with your first purchase 👉piquelife.com/richroll Roka: Unlock 20% OFF your order with code RICHROLL 👉ROKA.com/RICHROLL Bragg: Use code RICHROLL for 20% off your first order 👉Bragg.com Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

27 Maalis 1h 58min

The Explorer's Gene: Alex Hutchinson On Humanity’s Drive To Seek The Unknown, The Science Of Uncertainty, & Why Effort Creates Meaning

The Explorer's Gene: Alex Hutchinson On Humanity’s Drive To Seek The Unknown, The Science Of Uncertainty, & Why Effort Creates Meaning

Alex Hutchinson is a National Magazine Award-winning journalist, Cambridge-trained physicist, and bestselling author of “Endure” and “The Explorer’s Gene.” This conversation explores Alex’s transcendent perspective on our primordial drive to seek the unknown. We unpack his fascinating evolution from elite runner and NSA researcher to becoming the voice on endurance science, and now, the cartographer of humanity’s exploratory impulse. We dive into the genetic and neurological drivers of uncertainty-seeking, the importance of embracing difficulty, the role of play, and finding meaning through effort in adventure and everyday life. Note: In celebration of Alex’s appearance on the podcast, we’re giving away five signed copies of his transformative book. Subscribe to the newsletter at richroll.com/subscribe for a chance to win. Alex’s work doesn’t merely inform—it transforms. This dialogue is an expedition worth taking. Enjoy! Show notes + MORE  Watch on YouTube Newsletter Sign-Up   Today’s Sponsors: AG1: Get a FREE bottle of Vitamin D3+K2 AND 5 free AG1 Travel Packs 👉drinkAG1.com/richroll This episode is brought to you by BetterHelp: Get 10% OFF the first month👉BetterHelp.com/richroll   Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

24 Maalis 2h 20min

Introducing Ask Lisa: The Psychology of Parenting: "Should I Talk with My Teens About My Own Mental Health Challenges?"

Introducing Ask Lisa: The Psychology of Parenting: "Should I Talk with My Teens About My Own Mental Health Challenges?"

Today I’m sharing an episode of Ask Lisa: The Psychology of Parenting hosted by Dr. Lisa Damour and Reena. In this episode, Dr. Lisa Damour and Reena explore the topic of "Should I Talk with My Teens About My Own Mental Health Challenges?" Subscribe to Ask Lisa: The Psychology of Parenting on Spotify and Apple Podcasts. Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

20 Maalis 59min

Good Stress: Jeff Krasno On The Health Benefits of Deliberate Discomfort, How To Have Hard Conversations & Applying Eastern Wisdom To Western Medicine

Good Stress: Jeff Krasno On The Health Benefits of Deliberate Discomfort, How To Have Hard Conversations & Applying Eastern Wisdom To Western Medicine

Jeff Krasno is a wellness entrepreneur, author of “Good Stress,” and co-founder of the iconic global yoga festival Wanderlust.   This conversation explores Jeff’s journey from “wealth and hellness” to authentic well-being. His thesis on hormetic stress offers an antidote to our convenience-obsessed world. We discuss the political horseshoeing of wellness, the metaphysical Tao of Health, and how embracing discomfort forges both physiological and psychological resilience.   Note: In celebration of Jeff’s appearance on the podcast, we’re giving away four signed copies of his transformative book. Subscribe to the newsletter at richroll.com/subscribe for a chance to win.   Jeff's journey offers valuable insights on stress and adaptation. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today’s Sponsors: Go Brewing: Use the code Rich Roll for 15% OFF 👉gobrewing.com Roka: Unlock 20% OFF your order with code RICHROLL 👉ROKA.com/RICHROLL Prolon: Get 15% OFF plus a FREE bonus gift 👉 prolonlife.com/richroll Birch: Get 20% OFF sitewide 👉BirchLiving.com/richroll Bragg: Use code RICHROLL for 20% off your first order 👉Bragg.com  Ollie: Use code RICHROLL to get 60% off your Welcome Kit👉Ollie.com/RICHROLL   Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors

17 Maalis 2h 19min

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