Will Taking GH Before Going To Sleep Suppress Your Natural Production Of GH?
More Plates More Dates13 Helmi 2020

Will Taking GH Before Going To Sleep Suppress Your Natural Production Of GH?

At supraphysiological dosages, taking GH before going to sleep makes sense because there is a negative feedback loop on the growth hormone (GH)/insulin-like growth factor I (IGF-1) axis. In this study, IGF-1 was constantly infused, and the effect on endogenous GH secretion was assessed [R]. Overall, GH concentrations were suppressed during the rhIGF-I infusion by 85±3%, mainly by attenuating spontaneous GH pulse amplitude (77±4% suppression). The apparent GH pulse frequency was attenuated from 7.8±0.9 to 4.7±0.6 pulses/24h (P= 0.006). IGF-1 is the primary feedback, and the mechanism is similar to what you see with the HPTA axis. When there is enough Testosterone and Estrogen, your body has this mechanism in place to prevent you from making more. The same thing happens with exogenous GH use. When you administer exogenous GH, IGF-1 elevates. When your body recognizes that IGF-1 is elevated, it starts to suppress GH pulse amplitude in a dose dependent manner. If you are using supraphysiological amounts of GH for bodybuilding purposes, you can assume that your natural secretion is greatly inhibited during sleep as this negative feedback loop will prevent your body from secreting GH in your sleep like it normally would. When endogenous GH production is suppressed, administering exogenous GH at times that lipolysis or muscle growth can be optimized is the most logical approach to injection timing. https://youtu.be/8j9MGfQPeXg If fat loss is the goal, then taking GH in a fasted state prior to fasted cardio would be ideal. There is a ceiling on how much GH is needed to maximize lipolysis, so if your dosage exceeds 2 IU per day, then I would advise splitting up that dose into two (or more if needed) different periods of the day with as much time between them as possible. If muscle growth is the goal, GH should still be administered in a pulsatile fashion to mimic endogenous secretions. Topped out stimulation of autocrine IGF-1 in skeletal muscle can be achieved with fairly low dosages of exogenous GH, and administering a higher dose above and beyond that may just be a waste. This is why it would be wise to split up your daily GH dose into multiple administrations if you are using supraphysiological dosages. Learn more about your ad choices. Visit megaphone.fm/adchoices

Jaksot(1361)

Paul Saladino Getting Railroaded By "The Doctors" On TV

Paul Saladino Getting Railroaded By "The Doctors" On TV

Learn more about your ad choices. Visit megaphone.fm/adchoices

18 Huhti 202214min

How To Cure Jada Pinkett Smith's Alopecia Areata & Leaky Gut Explained - Paul Saladino Weighs In

How To Cure Jada Pinkett Smith's Alopecia Areata & Leaky Gut Explained - Paul Saladino Weighs In

Learn more about your ad choices. Visit megaphone.fm/adchoices

18 Huhti 202214min

Paul Saladino On The New Controversial Metformin Study And Diabetes

Paul Saladino On The New Controversial Metformin Study And Diabetes

Learn more about your ad choices. Visit megaphone.fm/adchoices

17 Huhti 202215min

Paul Saladino On Liver King & If Medications/Supplements Can Substitute As Hormetic Stressors

Paul Saladino On Liver King & If Medications/Supplements Can Substitute As Hormetic Stressors

Learn more about your ad choices. Visit megaphone.fm/adchoices

17 Huhti 202217min

Paul Saladino's Routine To Get Optimal Sleep Quality (lights, EMF, diet, circadian rhythm, etc.)

Paul Saladino's Routine To Get Optimal Sleep Quality (lights, EMF, diet, circadian rhythm, etc.)

Learn more about your ad choices. Visit megaphone.fm/adchoices

17 Huhti 202210min

Paul Saladino's Macros That Keep Him Shredded And Daily Routine For Productivity

Paul Saladino's Macros That Keep Him Shredded And Daily Routine For Productivity

Learn more about your ad choices. Visit megaphone.fm/adchoices

17 Huhti 20229min

Greg O'Gallagher - Natty Or Not, How To Get Jacked & Strong, Blood Work & Advice To Young Men

Greg O'Gallagher - Natty Or Not, How To Get Jacked & Strong, Blood Work & Advice To Young Men

Greg's Instagram: https://www.instagram.com/gregogallagher/ Greg's YouTube Channel: https://www.youtube.com/c/Kinobody ———————————— 🥬 To get a 1 year supply of Vitamin D3 & K2 + 5 individual travel packs for free with your first purchase, go to https://athleticgreens.com/moreplatesmoredates 💊 Use code DEREK at checkout for 15% off your first month's supply of Seed's Daily Synbiotic: https://thld.co/seed_derek_0422 ———————————— 🕑 Time Stamps: 0:00 - Steroid Accusations And How He Healed His Ruthless Elbow Tendinitis 9:16 - Lifting Only 3 Days A Week For Maximum Gains - How To Gain Muscle & Strength 37:53 - How Long It Takes To Reach Your Genetic Limit And How To Beat PR's Once You've Plateaued 55:23 - How Much Faster Would You Get To Your Genetic Peak If You Didn't Cut 1:02:09 - How Greg O'Gallagher Stays Below 10% Body Fat Year Round Naturally Without Doing Cardio Or 10,000 Steps 1:30:00 - Number 1 Piece Of Advice For Young Men 1:44:56 - Testosterone Makes Effort Feel Good, Sleep Regimen & Edibles Crushing Motivation 1:54:49 - Scientifically Dismantling Greg O'Gallagher's Blood Test Results ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— #moreplatesmoredates #gregogallagher #kinobody ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

17 Huhti 20223h 15min

Paul Saladino - The TRUTH About "Mental Clarity" On Ketogenic Diets And Eating Sugar With Red Meat

Paul Saladino - The TRUTH About "Mental Clarity" On Ketogenic Diets And Eating Sugar With Red Meat

Learn more about your ad choices. Visit megaphone.fm/adchoices

15 Huhti 202210min

Suosittua kategoriassa Koulutus

rss-murhan-anatomia
voi-hyvin-meditaatiot-2
psykopodiaa-podcast
rss-valo-minussa-2
adhd-podi
psykologia
rss-narsisti
rss-niinku-asia-on
rss-duodecim-lehti
aamukahvilla
kesken
rss-uskonto-on-tylsaa
rss-luonnollinen-synnytys-podcast
rahapuhetta
jari-sarasvuo-podcast
rss-liian-kuuma-peruna
rss-laadukasta-ensihoitoa
rss-ai-mita-siskopodcast
rss-vapaudu-voimaasi
mielipaivakirja