How Different Anabolic Steroids Can Affect Your Immune System And Vulnerability To Viral Infections

How Different Anabolic Steroids Can Affect Your Immune System And Vulnerability To Viral Infections

Both Testosterone and anabolic androgenic steroids (AAS) adversely influence the immune system, affecting leucocyte growth or activity, and antibody and cytokine production, particularly when used at supraphysiological doses, mimicking a condition of secondary immunodeficiency [R, R]. Secondary immunodeficiency, much more common than primary immunodeficiency (that is to say those caused by genetic defects affecting the cells of the immune system), is characterized by various factors that affect a normal immune system, including infectious, iatrogenic, metabolic and environmental factors. These immune deficiencies are manifested clinically with an increased frequency or unusual complications of common infections and occasionally with the onset of opportunistic pathogen infections. https://youtu.be/ceqSC6GYks4 Nandrolone And Anadrol Effects On The Immune System Nandrolone Decanoate and Anadrol directly induce the production of inflammatory cytokines Interleukin 1 Beta (IL-1β) and Tumor Necrosis Factor Alpha (TNF-α) in human peripheral blood leukocyte cultures [R]. Testosterone and DHEA had no direct cytokine inducing effect in the same model. Nandrolone Decanoate also inhibits interferon production in NDV-infected mouse L-929 and human WISH cells. Winstrol And Trenbolone Effects On The Immune System Winstrol and Trenbolone were found to be genotoxic and cytotoxic to human lymphocytes in a dose dependent manner [R]. Testosterone, Teslac, Anavar And Winstrol Effects On The Immune System To evaluate how anabolic steroids affect the immune system, five commercially available steroids with various types of structural differences were studied in a rodent model [R]. Animals were divided into five groups and treated with Testosterone (group 1), Testosterone Propionate (Group 2), the steroidal aromatase inhibitor Testolactone (Teslac) (Group 3), Anavar (Group 4), and Winstrol (Group 5). Significant immunosuppression was observed with all groups. However, by day 10, the Teslac, Anavar and Winstrol treated group showed immunostimulation and actually exceeded baseline immunity while the Testosterone treated groups maintained immunosuppressed. To truly test the effects of endogenous androgens on the immune system a second experiment was then performed. Ten animals maintained in a similar manner to the initial experiment were either treated intact or were castrated and then treated for 8 days, with Anavar (1.1 mg/kg/day), Testosterone (1.1 mg/kg/day) or Anavar combined with physiologic amounts of Testosterone (15 μg/day). Anavar was selected because it has the greatest anabolic activity of all Testosterone analogues as compared to Testosterone (androgenic/anabolic activity = 1:13). In the intact animals after 8 days of treatment with Anavar, serum Testosterone levels were measured by radioimmunoassay on tail vein blood. Levels were either undetectable or very low, reflecting what would be significant HPTA suppression. Immune function (DCH responses) measured at the same time revealed a 41% increase over baseline. The Testosterone treated group experienced a 36% suppression of immune function. Further treatment for 8 days with Anavar combined with physiologic amounts of Testosterone eliminated the immune system enhancement provided by Anavar monotherapy and returned the DCH responses to levels that were not significantly different from baseline. The results were different in the castrated animals. Castration, resulted in an increase in immune (DCH) responses. The mean observed change was 90% greater than intact (pre-castration) baseline. That means that castrated rats had a 90% improvement above and beyond rats that weren’t castrated. Eight day administration of Anavar to these animals had an immunodepressive effect returning the DCH response to baseline. Eight day treatment with Anavar combined with physiologic doses of Testosterone produced an even greater suppression, 45% change from baseline. These observations indicate that immune alterations do occur with anabolic steroids which are immunosuppressive when the steroid nucleus is intact and immunostimulatory with nuclear alterations. How Steroids Influence Immune Function The hypothesis to explain the immune system responses to steroids is as follows. Exogenous androgenic anabolic steroids produce two effects on the immune system: (A) a direct early effect on immune function which is suppressive and, (B) an indirect delayed stimulatory effect mediated through the negative feedback on the pituitary. (B) results in inhibition of gonadal Testosterone through diminished LH release. A decrease in the synthesis of Testosterone results in low serum Testosterone level and immune stimulation. Castration, by abolishing the modulation of Testosterone secretion eliminates the effect of (B) but leaves (A) intact. In summation, the more suppressive a steroid is the more it can indirectly enhance immune function, simply by suppressing the endogenous production of Testosterone and its metabolites. However, anabolic steroids will also be genotoxic and cytotoxic to human lymphocytes in a dose dependent manner. So, the only reason anabolic steroids can enhance immunity is by being more tissue selective than Testosterone and by shutting down the HPTA, not by inherently being protective. They too will be inherently immunosuppressive, just to a lesser degree based on their tissue selectivity and magnitude of impact on endogenous androgen production suppression. At the end of the day, the data all suggests that the lower your levels of steroids are in the body, the higher level your immune system will function at in parallel. Are You Increasing Your Risk Of Viral Infection When You Are On Cycle? In summary, the vast majority of studies suggest that steroid use decreases antibody formation, Natural Killer (NK) lymphocyte activity, T and B lymphocyte maturation and stimulation resulting in immunosuppression [R]. Supraphysiological doses of common anabolic steroids have been shown to directly influence the production of certain cytokines, altering immune function. The results from both animal and human studies suggest that supraphysiological doses of AAS can negatively impact the immune system. The takeaway from all of this is that with an easily spread virus infecting thousands of people throughout the world right now, it would be prudent to reduce your exogenous AAS use at least down to therapeutic levels to support immune function during this time where having increased vulnerability to viral infection is the most risky. Regardless if you are young and believe you are invincible based on the mortality rate statistics showing that the elderly are the most at risk of being symptomatic or ending up in critical condition, you may still be increasing your chances of becoming an infected carrier who then transmits the virus to the elderly (including your parents or grandparents) as a result of self-induced immunosuppression. Learn more about your ad choices. Visit megaphone.fm/adchoices

Jaksot(1360)

Jeff Seid Explains Why It's Obvious He's Natty

Jeff Seid Explains Why It's Obvious He's Natty

📩 My private email list for written articles, exclusive offers, sales & more: http://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Gorilla Mind - My Pre-Workout, Nootropic, Performance & Health Focused Formulas) discount code "MPMD" for 10% off your entire order ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic infused energy drinks) 💡 https://intelligent.shop/derek (Intelligent Shop - Gorilla Mind's Sister Company For Niche Products) discount code "MPMD" for 10% off your entire order ⚕️ My Preventive Medicine & HRT Clinic: https://bit.ly/373k791 🧪 Blood Work: http://bit.ly/2wI3k9J | discount code "MPMD" for 10% off your entire order 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | discount code "MPMD" for 10% off your entire order 🧴 Intelligent Minoxidil | The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | discount code "MPMD" for 10% off your entire order ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 🧴 The Skincare Products I Use: https://bit.ly/3pdS2DO - discount code "MPMD" for 10% off your entire order 🥩 The Best Newbie Friendly Diet For Muscle Growth (hits macros and micros): http://bit.ly/2JmpTGv 🧵 https://www.youngla.com/ (YoungLA Fitness & Lifestyle Clothing) discount code "MPMD" for 15% off your entire order ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ THREADS: https://www.threads.net/@moreplatesmoredates FACEBOOK: https://www.facebook.com/moreplates/ SNAPCHAT: https://www.snapchat.com/add/derek-fit TWITTER: https://twitter.com/Derek_Fitness TIKTOK: https://www.tiktok.com/@moreplates ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— #jeffseid #nattyornot #naturalbodybuilding  ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

7 Kesä 202441min

Did Messi Rip Off Prime?

Did Messi Rip Off Prime?

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6 Kesä 202411min

"I F***ING LOVE STEROIDS" - Ryan Garcia ABSOLUTELY Took Ostarine (positive B sample) | My Analysis

"I F***ING LOVE STEROIDS" - Ryan Garcia ABSOLUTELY Took Ostarine (positive B sample) | My Analysis

📩 My private email list for written articles, exclusive offers, sales & more: http://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Gorilla Mind - My Pre-Workout, Nootropic, Performance & Health Focused Formulas) discount code "MPMD" for 10% off your entire order ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic infused energy drinks) 💡 https://intelligent.shop/derek (Intelligent Shop - Gorilla Mind's Sister Company For Niche Products) discount code "MPMD" for 10% off your entire order ⚕️ My Preventive Medicine & HRT Clinic: https://bit.ly/373k791 🧪 Blood Work: http://bit.ly/2wI3k9J | discount code "MPMD" for 10% off your entire order 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | discount code "MPMD" for 10% off your entire order 🧴 Intelligent Minoxidil | The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | discount code "MPMD" for 10% off your entire order ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 🧴 The Skincare Products I Use: https://bit.ly/3pdS2DO - discount code "MPMD" for 10% off your entire order 🥩 The Best Newbie Friendly Diet For Muscle Growth (hits macros and micros): http://bit.ly/2JmpTGv 🧵 https://www.youngla.com/ (YoungLA Fitness & Lifestyle Clothing) discount code "MPMD" for 15% off your entire order ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ THREADS: https://www.threads.net/@moreplatesmoredates FACEBOOK: https://www.facebook.com/moreplates/ SNAPCHAT: https://www.snapchat.com/add/derek-fit TWITTER: https://twitter.com/Derek_Fitness TIKTOK: https://www.tiktok.com/@moreplates ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— #ryangarcia #boxing #peds ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

25 Touko 202416min

Drugs, Diets, & Training Protocols Of The World's Best Bodybuilders & Powerlifters - Stan Efferding

Drugs, Diets, & Training Protocols Of The World's Best Bodybuilders & Powerlifters - Stan Efferding

0:00:00 - 0:03:38 – What Is “The Vertical Diet”? 0:03:38 - 0:09:53 – 98 Pounds In High School - How Stan Delayed Puberty By Not Eating Or Sleeping Enough 0:09:53 - 0:12:43 – 145 ng/dL Testosterone Level At 20 Years Old – Discovering His Varicocele, Hypogonadism Diagnosis, And Getting On Testosterone 0:12:43 - 0:14:58 – The Steroid Cycle Stan Used In The 90’s To Get To Nearly 300 Pounds 0:14:58 - 0:18:33 – How To Determine If You Have IFBB Pro Bodybuilder Caliber Genetics 0:18:33 - 0:20:27 – Stan’s Thoughts On Cycling Off Vs. Blasting And Cruising 0:20:27 - 0:21:28 – The Results Of Stan’s Varicocele Surgery   0:21:28 - 0:25:00 – Female Softball Players Who Became Anemic From Removing Red Meat, Dairy, Fruit, And Egg Yolks 0:25:00 - 0:30:03 – Sponsor: Marek Health 0:30:03 - 0:34:22 – Bulking And Cutting Mistakes Preventing Progress 0:34:22 - 0:36:13 – When Are You Too Fat To Bulk? 0:36:13 - 0:44:09 – Permabulking And Staying Healthy While Pushing The Scale 0:44:09 - 0:44:45 – Mitchell Hooper’s Diet For The World’s Strongest Man 0:44:45 - 0:45:40 – Dairy 0:45:40 - 0:46:33 – Fermented Foods - Yogurt, Kefir, Kimchee, Gut Microbiome 0:46:33 - 0:49:48 – Keto Diet Advocates Who Transitioned Back To Including Carbs 0:49:48 - 0:54:04 – The Majority Of Health Benefits From Any Diet Coming From Weight Loss 0:54:04 - 0:55:32 – Paul Saladino’s Bold Assertion About APOB And Metabolic Health 0:55:32 - 0:59:05 – Anthony Chaffee, People With High LDL-C Live Longer? 0:59:05 - 1:03:26 – How Dana White ACTUALLY Transformed (weight loss and TRT) – Gary Brecka’s Wild Claims 1:03:26 - 1:04:53 – Addressing Vitamin Deficiencies 1:04:53 - 1:09:38 – The Ideal Protein Intake For Steroid Users Vs. Nattys 1:09:38 - 1:14:15 – The Best Diet For Weight Loss 1:14:15 - 1:16:38 – One Of The Main Ways Diet Can Lead To Ruthless Brain Fog 1:16:38 - 1:20:02 – The Utility Of Continuous Glucose Monitors (CGM’s) 1:20:02 - 1:20:44 – Why It’s Worthwhile To Count Calories (at least for a bit) 1:20:44 - 1:26:31 – Are Seed Oils Actually Unhealthy? 1:26:31 - 1:28:11 – How Hafþór Júlíus Björnsson Got Up To A Healthier 440 Pounds 1:28:11 - 1:33:39 – After Losing Weight Should You Stop Using Your CPAP Machine For Sleep Apnea? 1:33:39 - 1:38:31 – “It Was Absolutely Horrible!” - Stan Describes Coming Off Testosterone After 10 Years 1:38:31 - 1:41:33 – Why Stan Decided To Go Back On Steroids In 2006 At 39 Years Old 1:41:33 - 1:45:24 – The Steroid Cycle, Training, & Diet Flex Wheeler Put Stan Efferding On To Win His IFBB Pro Card In Bodybuilding 1:45:24 - 1:48:14 – Powerlifter Vs. Bodybuilder Steroid Use - Stan’s 2009 Stack To Hit A 2,221.2 Pound Total 1:48:14 - 1:56:17 – Getting Stronger But Not Getting Bigger - The “Horrible Lesson” IFBB Pro Stan Efferding Learned About Muscle Growth 1:56:17 - 2:01:38 – The Biggest Steroid Cycle Stan Efferding Has Ever Ran And What Happened - At A Point, Less Is More 2:01:38 - 2:03:43 – Can You Grow Muscle On Steroids Without Even Training? 2:03:43 - 2:05:36 – The Steroid Dosages IFBB Pro Bodybuilders Typically Take 2:05:36 - 2:11:30 – How Stan Approaches His Steroid Use And Training Now At 56 Years Old 2:11:30 - 2:15:48 – Stan’s Experience Using Growth Hormone And Insulin 2:15:48 - 2:18:25 – Stan’s Updated Recommendations On Sodium Intake 2:18:25 - 2:19:51 – Stan’s Updated Opinion On Seed Oils And Getting Sufficient Omega 3’s 2:19:51 - 2:28:10 – An Example Full Day Of Vertical Diet Eating For The Average Guy Trying To Gain Muscle 2:28:10 - 2:38:34 – The Most Impactful Changes Stan Made Working With Jon Jones, Hafþór Björnsson, Brian Shaw, Lane Johnson, Henry Cejudo, Mitchell Hooper, Gordon Ryan, And Other Elite Athletes He’s Worked With 2:38:34 - 2:44:08 – Organic Food Is A Scam? How Much Of A Difference Is There In Quality Between Organic Vs. Conventional Meat, Eggs, Fruit, And Vegetables? Grass-Fed Vs. Grain-Fed Beef. Fresh Vs. Frozen Fruit. 2:44:08 - 2:45:15 – Where To Buy The Vertical Diet 4.0 And Where To Follow Stan For More Information Learn more about your ad choices. Visit megaphone.fm/adchoices

21 Touko 20242h 45min

Paul Saladino - Quitting The Carnivore Diet After 2 Years And Avoiding Atherosclerosis

Paul Saladino - Quitting The Carnivore Diet After 2 Years And Avoiding Atherosclerosis

🛌 Use my Eight Sleep code "MPMD" for $200 off the Pod 4, or $350 off the Pod 4 Ultra: https://www.eightsleep.com/moreplatesmoredates/  ⚕️ Use code "MPMD" to get 10% off my go-to "Complete Panel" blood test, with a lab review included to interpret the results: https://marekhealth.com/mpmd  ———————————— 🕑 Time Stamps:  0:00:00 – 0:00:50 – Introduction  0:00:50 – 0:05:32 – Why Paul Saladino Stopped The Carnivore Diet After 2 Years  0:05:32 – 0:08:41 – Is There Ever A Point Of Doing A Keto Diet?  0:08:41 – 0:11:21 – Why Paul Reached Out To Me To Do A Second Podcast After Seeing Me Speak With Peter Attia  0:11:21 – 0:17:36 – What Actually Causes Atherosclerosis? Paul’s Take On The Traditional Hypothesis  0:17:36 – 0:22:17 – Should We Ignore High LDL-C Or APOB?  0:22:17 – 0:25:05 – Paul Describes How Some Studies Suggest That Those With Higher HDL-C Levels May Be Less Likely To Get Atherosclerosis Despite Having High LDL-C Levels  0:25:05 – 0:25:26 – Paul’s Perspective On Why Many Doctors Aren’t Educating Their Patients About Metabolic Health  0:25:26 – 0:33:41 – "Ignore Nutrition Just Focus On Exercise"  0:33:41 – 0:37:55 – Sponsor: Eight Sleep  0:37:55 – 0:39:02 – The Most Important Lab Tests For Avoiding Atherosclerosis  0:39:02 – 0:42:53 – Is It Possible To Get Atherosclerosis If You Have A Fasting Insulin Of 3 uIU/mL Or Less 0:42:53 – 0:46:27 – Familial Hypercholesterolemia (FH) And Why It’s A Phenotypic Diagnosis, Not A Genotypic Diagnosis 0:46:27 – 0:49:41 – What Happens When You Replace Saturated Fat With Linoleic Acid? 0:49:41 – 0:52:38 – How A Pure Carnivore Diet Affects Thyroid Metabolism 0:52:38 – 0:56:45 – Can Someone On A Keto Diet Long-Term Develop Atherosclerosis Despite Having A Low Fasting Insulin? Dave Feldman’s Lean Mass Hyper-Responder Study 0:56:45 – 1:00:56 – How Paul’s Perspective Differs From Dave Feldman and Shawn Baker     • The Baseline Data From The LMHR Study Paul Mentioned:         https://twitter.com/realDaveFeldman/status/1733387107610063195 1:00:56 – 1:03:55 – What Is APOB And LP(a)? 1:03:55 – 1:06:44 – Sponsor: Marek Health 1:06:44 – 1:10:21 – How Long It Takes For Plaque To Develop And Show On A CT Angiogram 1:10:21 – 1:13:46 – Why Paul Uses Proxy Biomarkers In Atherosclerosis Data Analysis To Discern Insulin Sensitivity 1:13:46 – 1:18:14 – Does Paul Think It Is Ever Justified To Take Lipid Lowering Medication To Avoid Atherosclerosis? 1:18:14 – 1:20:13 – How Should You Track If You Are Developing Atherosclerosis? 1:20:13 – 1:45:27 – Lipid Lowering Medication Risk-Reward Analysis. Will Lowering LDL-C Impair Quality Of Life, Regardless Of The Medication Used? Do Adolescents With Hypofunctioning PCSK9 And Very Low APOB Have Impaired Development Cognitively Or Structurally? 1:45:27 – 1:47:39 – If You Don’t Lower APOB But Want To Track Plaque Accumulation, Is The Dose Of Radiation From A CT Angiogram Concerning? 1:47:39 – 1:56:45 –Why Certain Tribes Have Lower Rates Of Cardiovascular Disease Than The Average Person. Should Or Shouldn’t We Copy What They’re Doing? 1:56:45 – 2:16:17 – The Lowest Hanging Fruit For Avoiding Atherosclerosis And Evaluating Your Risk ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

8 Touko 20242h 16min

"GET YOUR HEAD TOGETHER OR K*LL YOURSELF" - Conor McGregor

"GET YOUR HEAD TOGETHER OR K*LL YOURSELF" - Conor McGregor

📩 My private email list for written articles, exclusive offers, sales & more: http://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Gorilla Mind - My Pre-Workout, Nootropic, Performance & Health Focused Formulas) discount code "MPMD" for 10% off your entire order ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic infused energy drinks) 💡 https://intelligent.shop/derek (Intelligent Shop - Gorilla Mind's Sister Company For Niche Products) discount code "MPMD" for 10% off your entire order ⚕️ My Preventive Medicine & HRT Clinic: https://bit.ly/373k791 🧪 Blood Work: http://bit.ly/2wI3k9J | discount code "MPMD" for 10% off your entire order 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | discount code "MPMD" for 10% off your entire order 🧴 Intelligent Minoxidil | The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | discount code "MPMD" for 10% off your entire order ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 🧴 The Skincare Products I Use: https://bit.ly/3pdS2DO - discount code "MPMD" for 10% off your entire order 🥩 The Best Newbie Friendly Diet For Muscle Growth (hits macros and micros): http://bit.ly/2JmpTGv 🧵 https://www.youngla.com/ (YoungLA Fitness & Lifestyle Clothing) discount code "MPMD" for 15% off your entire order ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ THREADS: https://www.threads.net/@moreplatesmoredates FACEBOOK: https://www.facebook.com/moreplates/ SNAPCHAT: https://www.snapchat.com/add/derek-fit TWITTER: https://twitter.com/Derek_Fitness TIKTOK: https://www.tiktok.com/@moreplates ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— #ryangarcia #boxing #conormcgregor  ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

4 Touko 202415min

Ryan Garcia Took PED's - My Analysis

Ryan Garcia Took PED's - My Analysis

📩 My private email list for written articles, exclusive offers, sales & more: http://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Gorilla Mind - My Pre-Workout, Nootropic, Performance & Health Focused Formulas) discount code "MPMD" for 10% off your entire order ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic infused energy drinks) 💡 https://intelligent.shop/derek (Intelligent Shop - Gorilla Mind's Sister Company For Niche Products) discount code "MPMD" for 10% off your entire order ⚕️ My Preventive Medicine & HRT Clinic: https://bit.ly/373k791 🧪 Blood Work: http://bit.ly/2wI3k9J 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | discount code "MPMD" for 10% off your entire order 🧴 Intelligent Minoxidil | The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | discount code "MPMD" for 10% off your entire order ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 🧴 The Skincare Products I Use: https://bit.ly/3pdS2DO - discount code "MPMD" for 10% off your entire order 🥩 The Best Newbie Friendly Diet For Muscle Growth (hits macros and micros): http://bit.ly/2JmpTGv 🧵 https://www.youngla.com/ (YoungLA Fitness & Lifestyle Clothing) discount code "MPMD" for 15% off your entire order ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ THREADS: https://www.threads.net/@moreplatesmoredates FACEBOOK: https://www.facebook.com/moreplates/ SNAPCHAT: https://www.snapchat.com/add/derek-fit TWITTER: https://twitter.com/Derek_Fitness TIKTOK: https://www.tiktok.com/@moreplates ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— #ryangarcia #boxing #peds ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

3 Touko 202433min

Peter Attia - Full Daily Routine, Top 10 Supplements and Dr*gs, Heart Disease, Cancer and F1

Peter Attia - Full Daily Routine, Top 10 Supplements and Dr*gs, Heart Disease, Cancer and F1

Time Stamps: 00:00:00 - Peter Attia’s new book ‘Outlive’ 00:02:26 - Who is Peter Attia? What is Medicine 3.0? 00:03:28 - Peter Attia’s career. How did he become a doctor? And how did he evolve into his unique approach to preventative medicine? 00:07:54 - What do the acronyms in Peter’s Instagram bio stand for? 00:13:53 - The Four Horseman of Death (most will die from one of these) 00:22:46 - How to not die from atherosclerotic disease (the leading cause of death) 00:29:59 - The impact of smoking on atherosclerotic disease 00:30:36 - The impact of high blood pressure (hypertension) on atherosclerotic disease, how common it really is, and how to track it 00:32:32 - The accuracy of manual vs. automatic blood pressure cuffs 00:35:41 - The impact of APOB/all atherogenic particles (LDL’s, LP(a)’s, VLDL’s, and IDL’s) on atherosclerotic disease 00:40:57 - The minimum APOB level needed for adequate function 00:42:43 - PCSK-9 gene and its effect on LDL. How PCSK-9 inhibitors work to lower LDL 00:43:24 - APOB vs. APOA 00:44:56 - The most effective lipid managing dr*gs for preventing atherosclerosis 00:50:16 - Why Peter doesn’t see a reason why anybody should have an APOB over 60 mg/dL 00:52:15 - If Peter could go back in time knowing what he knows now and with modern pharmacology, at what age would he start lowering his APOB 00:55:04 - Arterial plaque accumulation starts as early as when you are a teenager. Calcification takes years to show up on a coronary CT calcium scan, but that does not mean plaque isn’t accumulating 00:57:12 - Should you screen for atherosclerosis before taking medication? If so, how?  01:01:06 - Why are carnivore diet zealots so dogmatic about cholesterol and atherosclerosis? What does the data show to date? 01:06:05 - If those with average genetics maintain a near perfect diet, exercise regimen and sleep hygiene, will many of those individuals still develop atherosclerosis? 01:09:41 - How to lower blood pressure 01:13:25 - Sleep Apnea and the use of CPAP 01:16:49 - Cancer: Causes, Prevention, and Proactive Screening  01:35:53 - The devices and metrics Peter uses to track his sleep and recovery 01:41:50 - Resting heart rate, HRV, heart rate recovery, and how predictive they are of mortality 01:44:43 - Peter's full daily routine and diet 01:54:35 - Why Peter stopped fasting 01:57:12 - Bodybuilders abuse of T3, Clen, DNP, and other metabolic modulators 01:58:54 - Peter breaks down his 6000+ calorie diet, 6 hours of daily exercise, and the most absurd meals he ate to maintain his weight when he was younger 02:01:25 - How Peter’s kids eat. How strict should the diet be for your kids when it comes to food quality to maximize growth potential? 02:07:41 - Where is the best burger in Austin? 02:08:22 - What time Peter stops eating each night, and the hack he uses to prevent him from overeating 02:11:33 - Peter's non-negotiable nightly practices for maximizing sleep quality 02:12:31 - Why Peter has a Bat phone 02:14:29 - How to live in the moment and be happy. The vicious circle of financial success and/or accolades never being enough. 02:22:46 - How to decide if you should have kids 02:25:13 - Peter’s Top 10 Supplements and Top 10 Dr*gs 02:29:35 - Peter's personal supplement stack and dr*g protocol 02:42:26 - Homocysteine reduction protocol 02:44:11 - Vitamin B6 deficiency paradoxically caused by Pyridoxine Hydrochloride supplementation 02:46:00 - How safe is TRT for cardiovascular health? TRAVERSE clinical trial results 02:51:31 - Comparison of TRT administration methods. What Peter prefers for patients 02:52:40 - What podcasts and YouTube channels Peter likes to watch or listen to 02:55:09 - Formula 1 02:55:54 - AlphaTauri x Hugo Boss 02:56:21 - Daniel Ricciardo, Max Verstappen 02:59:33 - How Red Bull became such a dominant F1 team 03:01:35 - Sim racing 03:05:13 - How Peter got so interested in F1 03:06:33 - Peter’s dream car 03:06:50 - Ayrton Senna 03:08:25 - Outro Learn more about your ad choices. Visit megaphone.fm/adchoices

31 Loka 20233h 8min

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