Is Metformin Really Dangerous, Little-Known Peptides For Muscle Gain & Fat Loss, Testosterone Replacement Therapy & Much More!
Boundless Life21 Helmi 2019

Is Metformin Really Dangerous, Little-Known Peptides For Muscle Gain & Fat Loss, Testosterone Replacement Therapy & Much More!

Is metformin really as dangerous as it's been made out to be? What are the best peptides to use for muscle gain, fat loss and cognition? How can you get started with testosterone optimization therapy?

I answer all these questions and many more in this podcast with Jay Campbell, a Champion Men’s Physique Competitor and the best selling author of the Testosterone Optimization Bible and of The Definitive Testosterone Replacement Therapy Manual: How to Optimize Your Testosterone for Lifelong Health and Happiness... (along with a host of other books linked to in the resources section below).

As a 17 year TRT patient, Jay is a master at manipulating and tweaking the human endocrine system to optimize performance and health. He has experience working with thousands of men and women in optimizing their nutrition, exercise, fitness and fat loss. Jay makes it his personal mission to affect positive and rapid change in each and every client who enters the mastermind program.

During our absolutely epic discussion, you'll discover: -Jay's daily routine and why he eats only 3 days per week...
  • Metformin
  • Armour Desiccated Thyroid
  • Lion's Mane
  • Curcumin, turmeric,
  • Protein powder, MCT oil
  • Practice intermittent fasting if you're not fast-adapted or want to lose weight
  • The cold-filtration whey isolate Jay recommends...
    • 70% of people have some sort of response (allergic or otherwise) to whey protein
    • True Nutrition
    • Ben has used Mt. Capra
    • Cold filtration similar to micro-filtration for wine
    • Thorne Mediclear
-Jay's response to Ben's concerns about the use of Metformin...
  • Mitochondrial dysfunction
    • 2 studies by Dr. Chandler Mars
    • Morbidly obese diabetics using a disproportionate amount of Metformin
    • "Life extension dose" varies due to body size, ancestry, etc.
    • Jay has used Metformin for 17 years
    • Lactic Acidosis: studies done on samples not representative of the population
    • Gastric issues are a result of Metformin cleaning up microbiota
      • Subsides as the biome becomes used to Metformin
    • Metformin protects the brain and cleans vascular pathways
-How to go about getting Metformin...
  • Tell your doctor you want it because it's cardio-protective, prevents cancer and is believed to stop the progress of neuro-degenerative diseases such as Alzheimers
  • It's also very affordable
  • inhousepharmacy.vu
-Whether Berberine should be used, and if so, as an alternative or a supplement to Metformin...
  • Berberine is similar to Metformin, but isn't as regulated and is much more expensive
  • Berberine doesn't have a good reputation among people in the know
  • Metformin is the most studied drug in the world (because of diabetes)
-Jay's favorite peptides and what to look for when choosing a peptide for yourself...
  • Peptides are a great option for an aging man or woman to slow down aging process, increase sleep, etc.
  • Ipamorelin (GHRP)
    • Highest efficacy if combined with a growth hormone
    • Best peptide for women by far
  • Neanderthal genes
  • Quercetin
  • Tesamorelin
    • FDA approved; created by Merck
    • Created for HIV positive men for lipo dystrophy
    • Extremely expensive
    • Highly effective in eliminating body fat
  • Peptide fact sheet from Tailor Made Compounding
  • Sermorelin is useless
  • PeptideSciences
  • Semax as a nootropic
  • BP 157
  • Jay doesn't like:
    • Ibutamoren
    • GHRP 2 or 6
-Why Jay is taking Armour Thyroid...
  • Thyroid synergistic with hormones and testosterone
  • Desiccated Thyroid: Combo of T3 and T4
-Rapid fire questions on testosterone...
  • Is there a risk of cardio vascular health if one supplements their testosterone?
    • If a man is a "metabolic emergency," potential for an incident; because of that person's compromised health
    • Testosterone is cardio protective; beneficial for the heart for someone in good health
  • TRT as a nootropic
    • Testosterone increases dopamine signaling
    • Feeling of "well-being"
    • Improves working memory
  • Once you start using it, do you have to be on it for life?
    • Yes, but the individual's environment is vital
  • What's the best delivery mechanism?
    • Transscrotal application (absorbed 8x better in the scrotum skin)
  • What are you taking with testosterone to mitigate the downstream side effects?
    • World Link Medical
    • You need testosterone to aromatize into estrogen to confer the protective effects to your biological system
    • You'd never want to take an aromatase inhibitor
  • What should you be looking for in reference ranges, and what should you be monitoring when you're on testosterone?
-And much more! Resources from this episode:

-Jay's recent roundtable on peptides

-Jay's TRT Revolution podcast

-Jay's book: "Guaranteed Shredded"

-Men's Health Optimization Bundle

-Ultimate Fat Loss Bundle

-Jay's Facebook video about metformin

-Cold filtered whey protein

-Thorne Mediclear

-Kion energy bar

-True Nutrition whey protein

-My article on the dangers of metformin

-Jay's article on the benefits of metformin

-Jay's Facebook video on metformin

-Metformin Alters Microbiota, Improving Insulin Sensitivity

-Metformin Alters Gut Microbiota of Healthy Mice: Implication for Its Potential Role in Gut Microbiota Homeostasis

-Goat's Rue herb tea

-Extended release metformin from Inhouse pharmacy

-Berberine

-Kion Lean

-T.S. Wiley's book: Lights Out - Sleep, Sex & Survival

-My podcast on testosterone optimization from A4M in Vegas

-2020 A4M in Vegas

-Ben's peptide article: How To Use Growth Hormone Stacks For A Better Body: Everything You Need To Know About IGF-LR3, GHRP, and GHRH Peptide Stacks.

-Peptide fact sheet from Tailor Made Compounding

-Ben's article "Should You Get Growth Hormone Injections (And Will GH or IGF-1 Increase Your Cancer Risk)?"

-Thorne Quercetin

-Dr. Seed's oral BPC-157 (use ode BEN for 15% off entire product line)

-PeptideSciences

-Semax

-Testosterone for depression

-Amazon version of the Testosterone Optimization Bible

-Pharmacokinetics of testosterone cream applied to scrotal skin.

-My podcast with Anthony Jay - Estrogeneration: How Estrogenics Are Making You Fat, Sick, and Infertile.

-The DUTCH Hormone Panel

-DirectLabs

-Zach Bush's Restore

Other notes from Jay:

-Metformin Study: Mitochondrial Dysfunction

-This was on a thoroughly compromised patient population group of Morbidly Obese Diabetics who were using anywhere from 6-9 grams of Metformin per day. If you do further searches, it’s actually the opposite. Metformin reverses Mitochondrial Dysfunction. There are many, many others.

-Metformin Study: Lactic Acidosis - The fear of this condition happening was based on a study from the 40s (still attempting to find it) also in a massively compromised patient cohort. These patients were in end-stage renal failure and also obese and diabetic.

We must be mindful that correlation does not equate to causation. All of these linked studies show that Lactic Acidosis rarely happens if ever in normal patients population groups. Check them here, here and here.

Elevated plasma metformin concentrations (as occur in individuals with renal impairment) and a secondary event or condition that further disrupts lactate production or clearance (e.g., cirrhosis, sepsis, or hypoperfusion), are typically necessary to cause metformin-associated lactic acidosis (MALA). As these secondary events may be unpredictable and the mortality rate for MALA approaches 50%, metformin has been contraindicated in moderate and severe renal impairment since its FDA approval in patients with normal renal function or mild renal insufficiency to minimize the potential for toxic metformin levels and MALA. However, the reported incidence of lactic acidosis in clinical practice has proved to be very low (

See omnystudio.com/listener for privacy information.

Jaksot(1747)

Dry Sauna Vs Infrared Vs Hot Tub, Little Known Ways To Heal The Gut, Maintaining Muscle With Ketones and More! Solosode: 495

Dry Sauna Vs Infrared Vs Hot Tub, Little Known Ways To Heal The Gut, Maintaining Muscle With Ketones and More! Solosode: 495

Full Shownotes: https://bengreenfieldlife.com/podcast/495/ In this episode, I take you through a solo Q&A exploring topics like the best sauna practices, the real benefits of walking 7,000 steps a day, and the latest research on gut health treatments—including my personal experience starting a fecal microbiota transplant for chronic issues. How perceived food sensitivities can sometimes create real symptoms, clear up concerns about ketone supplements and liver health, and emphasize the importance of staying active throughout the day. I also mention my biohacking binder and let you know all the resources, studies, and tools I recommend will be linked in the show notes for anyone wanting more details. You’ll gain access to my complete binder of home biohacking tools and gadgets designed to support long-term health and performance (click here to start exploring). Episode Sponsors: IM8: Ditch the cabinet full of supplements—IM8 packs 92 powerhouse ingredients into one delicious scoop for all-day energy, gut health, and cellular support. Go to IM8Health.com and use code BEN for an exclusive gift—fuel your body the right way! Quantum Upgrade: Recent research has revealed that the Quantum Upgrade was able to increase ATP production by a jaw-dropping 20–25% in human cells. Unlock a 15-day free trial with the code BEN15 at quantumupgrade.io. Muse: Muse S Athena combines clinical-grade EEG and fNIRS technology to train your brain in real time while tracking sleep with 86% expert-level accuracy. Get 15% off at choosemuse.com/BENGREENFIELD or use code BENGREENFIELD at checkout. BIOptimizers Magnesium Breakthrough: The 7 essential forms of magnesium included in this full-spectrum serving help you relax, unwind, and turn off your active brain after a long and stressful day, so you can rest peacefully and wake up feeling refreshed, vibrant, and alert. Go to bioptimizers.com/ben and use code ben15 for 15% off any order. LMNT: Everyone needs electrolytes, especially those on low-carb diets, who practice intermittent or extended fasting, are physically active, or sweat a lot. Go to DrinkLMNT.com/BenGreenfield to get a free sample pack with your purchase!See omnystudio.com/listener for privacy information.

27 Joulu 202535min

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25 Joulu 202552min

The Hidden Damage That Happens "Behind-The-Scenes" In The Adult Entertainment Industry, With Former Adult Actress Felicity Feline

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Full Shownotes: BenGreenfieldLife.com/felicity Today’s guest, Felicity Feline, is a certified health coach, yoga instructor, professional drummer, and former adult actress. Felicity opens up about her journey through—and eventually out of—the porn industry, sharing a raw and honest perspective on the emotional and physical challenges she faced along the way. She and dives deep into the impact of the adult industry both on performers and consumers, discussing issues like mental health, addiction, relationships, and societal shifts with OnlyFans and digital content. Felicity also reveals her personal health and biohacking strategies, especially how she’s balanced late nights as a musician in LA with her commitment to wellness, clean nutrition, and restorative practices. Her story is a powerful blend of cautionary insight and practical advice, highlighting the need for self-awareness, resilience, and open communication—whether it’s about relationships, personal choices, or navigating modern social pressures. Episode Sponsors: Organifi Shilajit Gummies: Harness the ancient power of pure Himalayan Shilajit anytime you want with these convenient and tasty gummies. Get them now for 20% off at organifi.com/Ben. Truvaga: Balance your nervous system naturally with Truvaga's vagus nerve stimulator. Visit Truvaga.com/Greenfield and use code GREENFIELD30 to save $30 off any Truvaga device. Calm your mind, focus better, and recover faster in just two minutes. The Medicin: Immune Intel AHCC is a clinically studied shiitake mushroom extract that enhances immune cell communication through a patented fermentation process, creating highly bioavailable alpha-glucans. Backed by 30+ human studies and used in over 1,000 clinics worldwide, AHCC supports immune function for everyday wellness and chronic health challenges—learn more at TheMedicin.com and use code BEN for 10% off. Manukora: You haven’t tasted or seen honey like this before - so indulge and try some honey with superpowers from Manukora. If you head to manukora.com/ben or use code BEN, you’ll automatically get $25 off your Starter Kit. Sunlighten: Sunlighten's patented infrared sauna technology delivers the highest quality near, mid, and far infrared wavelengths to reduce inflammation, boost mitochondrial function, enhance detox pathways, and optimize recovery—backed by 25+ years of clinically proven, non-toxic innovation. Save up to $1,400 at get.sunlighten.com/ben with code BEN. Troscriptions: Explore Troscriptions' revolutionary buccal troche delivery system that bypasses digestion to deliver pharmaceutical-grade, physician-formulated health optimization compounds directly through your cheek mucosa for faster onset and higher bioavailability than traditional supplements. Discover a completely new way to optimize your health at troscriptions.com/BEN or enter BEN at checkout for 10% off your first order.See omnystudio.com/listener for privacy information.

20 Joulu 20251h 1min

Everything You Need To Know About SEED OILS (Including One Cool "Trick" To Make Them Less Damaging), With Dr. Nick Norwitz

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18 Joulu 202554min

How To COOL Your Body For Better Sleep, INCREDIBLE Travel Sleep Tips & Orion Vs. Eight Sleep With Dr. Michael Breus

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13 Joulu 202549min

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11 Joulu 20251h 8min

Optimizing Daily Habits: Snacking, Movement, Light Exposure, and More Wellness Hacks LIFE Network: RAW Podcast #3

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6 Joulu 202530min

How I "Hacked My Home": EMF Shielding, Grounded Floors, Protected Bedroom, The Healthiest Lighting & Much More with Brian Hoyer (Best of LIFE Network's Experts!)

How I "Hacked My Home": EMF Shielding, Grounded Floors, Protected Bedroom, The Healthiest Lighting & Much More with Brian Hoyer (Best of LIFE Network's Experts!)

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