The Truth About The Carnivore Diet: Everything You Need To Know About Dangers, Benefits, Mistakes & Hacks For Eating Only Meat.
Boundless Life14 Maalis 2019

The Truth About The Carnivore Diet: Everything You Need To Know About Dangers, Benefits, Mistakes & Hacks For Eating Only Meat.

Prepare yourself for the most epic, deep dive into the carnivore diet that you've ever heard.

I recently listened to a physician named Paul Saladino debate research scientist Layne Norton about the carnivore diet on my friend Mark Bell's podcast. I was so intrigued by the episode that I decided to get Paul on my show to explore the science behind the carnivore diet, carnivore diet do's and don'ts, and whether the carnivore diet is a true, sustainable, natural, ancestral nutrition approach or just a dietary fad.

During this show, we cover: -Why Paul is a raving fan of salmon roe...17:15
  • Humans cannot make Omega 3 fatty acids
    • Omega 3's in salmon roe are in the phospholipid form
    • Salmon roe crosses the blood brain barrier more efficiently than in the triglyceride or ethyl ester form (which you'll find in most fish oil capsules)
  • Two tbsps of salmon roe gives you the DHA without being exposed to the metals
  • Benefit of getting a nutrient from a food vs. from a supplement
  • Concern with oxidation in fish oil:
    • Look for certificate of analysis
    • Look at levels of lipid peroxides
    • Not nearly as much oxidation in eggs than the fish
-Why Paul doesn't consume black pepper...21:15
  • A central principle of the carnivorous diet: plants are not put on the earth to serve humans
  • Develop potentially toxic compounds to defend themselves from other animals
  • A peppercorn is the seed of a plant
    • The seeds are where a higher concentration of pesticides and toxins reside
    • Pepper contains a compound called piperine, which inhibits UDP glucuronosyltransferase
  • In essence: black pepper inhibits our body's natural detoxification process.
  • Piperine is added to curcumin supplements to increase the level of curcumin you can absorb
  • We don't actually use these molecules in human biochemistry
    • Used to activate certain pathways to produce our own antioxidants (which is glutathione)
  • Plants induce Nrf2, while simultaneously doing toxic things to our bodies
  • Sulforaphane is considered to be a highly beneficial molecule as a precursor to glutathione pathways
    • But is known to be a goitrogen (meaning it can induce hypothyroidism)
  • Key take away: You can simulate the benefits of eating plants by eating meat and living a healthy lifestyle
-Why Paul refused a cup of Kion Coffee when offered by Ben...30:45
  • Coffee is felt to be beneficial because of a couple of polyphenolic compounds: chloragenic acid and caffeic acid
  • A coffee bean is the seed of a plant, which contains toxins as a natural defense mechanism
  • Very few animals eat those seeds
-Aren't plants like exercise, where you need them, but too much can be harmful?...26:05
  • Hormesis is potential benefit of plants
  • Sulforaphane:
    • Is linked to hypothyroidism
    • Depends on one's baseline level of iodine consumption
    • Does not exist in a plant
    • Glucoraphanin is converted into sulforaphane by Myrosinase
      • Highest levels are found in broccoli seeds and sprouts
  • Humans are "facultative carnivores" meaning we can get everything we need from meat without ingesting the toxins found in plants.
-Storage organs in plants that result in larger brains and smaller guts...46:35
  • Richard Wrangham
  • Tubers
    • Fairly toxic generally speaking
    • Ancestral (non-hybridized) tubers aren't as valuable to humans due to size, appearance, etc.
    • Developed big brains by eating bone marrow and brains of animals (as scavengers)
    • No DHA, or fatty acids in a tuber
    • Macronutrients for short term survival; micronutrients for long term survival
    • Tubers have macronutrients, but not micronutrients
  • Fossils of homo erectus found near water: algae, DHA, other micronutrients
  • Just because tubers were efficacious for our ancestors doesn't mean we should choose them today
    • Animals provide all the micronutrients we need in the most bioavailable forms
    • The ultimate multivitamin for a human would be an animal
-Why plants may not be necessary, could be harmful to the gut, and are "survival food"...50:50
  • Vilhjalmur Stefansson: Lived with Inuit people for a year
    • Observed they ate plants only when "real foods" i.e. animals weren't available
  • Book: 100 Million Years of Food by Stephen Lee
  • Even though humans have made plants more digestible via sprouting, fermenting, etc. we should still opt for the ribeye steak.
-Whether a carnivorous diet is sustainable or ethical...53:53
  • Eat the animal "nose to tail"
  • Book: The Whole Beast by Fergus Henderson
  • Muscle meat is high in methionine but low in glycine
  • Best results come when we eat organs and tendons along with the muscle meat
    • Different nutrients in different parts of the animal
  • Why Ben called the carnivore diet "lazy" on the Joe Rogan podcast
  • Carbohydrate availability for the thyroid
    • Ancestors would eat the thyroid immediately after killing an animal
  • Do you need plants to consume adequate amounts of vitamins and minerals?
    • Good amounts of Vitamin C in liver and in brain; whale blubber
    • Liver also has large amounts of carotenal, a precursor to Vitamin A
    • Quercetin doesn't directly contribute to human biochemistry
    • You may not be able to get flavonoids from meat, but you may not need them at all
-How we would consume fiber on a carnivore diet, or if we even need it at all...1:06:40
  • The debate between Paul Saladino and Layne Norton on the Mark Bell show
  • Fiber is a "fairy tale"
    • Physician named Burkett in Tanzania
    • Tanzanians did not have as many cases of diverticulosis as Westerners
    • Erroneously equated high amounts of fiber intake with low cases of diverticulosis
    • The reverse is true
    • Applies to insoluble and soluble fiber
  • "Healthy user bias" affects studies on fiber
    • People who eat less meat and more fiber, and engage in healthy activities
    • Stereotypical "meat eater": Steak, fries, cake, etc.
-Why Ben Greenfield is hesitant to embrace a full-on carnivore diet...1:13:50
  • Variety is the spice of life (colors of food, tastes, etc.)
  • Humans are "facultative carnivores"
    • Meant to eat animals, but can eat plants when animals are not available
    • Plants can contribute to life enjoyment if you choose to use them in your diet
-The carnivore diet and longevity...1:23:30
  • Fallacy: centenarians live longer because of genetics. They live long in spite of what they eat.
  • Theory of "blue zones" has been incorrectly interpreted
    • Not caused by diet (plants, legumes, etc.)
    • Clusters of longevity mutation in certain genes; improves insulin sensitivity, antioxidants, etc.
  • High insulin sensitivity when carbs are cut out
-Carnivore vs. ketosis...1:28:45
  • Three micronutrients: carbs, protein, fat
  • We can run on two fuels: fat or carbs
    • fat that is stored or that you're eating
    • No such thing as an "essential carbohydrate"
  • You can have a ketogenic diet that includes some plant foods that are potentially immunotoxic
  • Carnivorous diet is by default a ketogenic because you're not eating plant-based carbs (trace amounts in meat)
  • What about coconut oil and coconut cream?
  • Dairy: addictive to humans because it's the combination of fat and sugar; great for infants
    • It's why we crave ice cream
    • Rewarding but not satiating
    • Some cut out dairy, and find they're more satiated when eating meat
-The carnivore diet and amino intake...1:37:53
  • Paul typically eats 3 pounds of meat per day
  • No risk of developing cancer
    • Eating methionine without glycine becomes problematic
    • Bone broth and collagen are good sources of glycine
-Concern about constant activation of mTor on the carnivorous diet...1:41:00
  • Concern about IGF-1 (insulin growth factor) levels raising on the diet
  • Paul has found the opposite to be true
  • Caloric restriction benefits come from sirtuin family of genes, which is activated by beta hydroxy butyrate
  • Balances out because of the ketogenic state of the diet
-Whether a carnivorous diet is sustainable or ethical...1:45:30
  • It's not practical for everyone to hunt their own meat
  • Look at it from a population vs. individual basis
    • Answer questions pertaining to the individual before the population
    • Advances in technology contribute to increases in greenhouse gases (fossil fuel emissions)
    • Agriculture contributes ~8% of greenhouse gases; 3-4% is animal agriculture
-And much more... -Who is Paul Saladino?

Throughout the course of his life Paul Saladino has embarked on many adventures that have shaped his personal interests - including his unique, individualized approach to medicine. After studying chemistry at College of William he spent 6 years traveling and exploring. Highlights included a thru-hike of the Pacific Crest Trail from Mexico to Canada, a summer in the New Zealand backcountry, and 2 years skiing and climbing in Wyoming's Teton Mountains. He returned to academic studies after these adventures, first becoming a physician assistant and practicing in cardiology before training at the University of Arizona, obtaining his M.D. in 2015.

He is a certified Functional Medicine practitioner (IFMCP) through the Institute for Functional Medicine and will complete his residency in psychiatry at the University of Washington this June. When he is not researching connections between nutritional biochemistry and chronic disease he can be found in the frigid waters of the pacific northwest in search of the perfect wave.

Resources from this episode:

-My Facebook post on my "bastardized version" of the carnivore diet

-Paul Saladino's website

-Paul Saladino's YouTube channel

-The debate between Paul Saladino and Layne Norton on the Mark Bell show

-USWellnessMeats ribeye steaks - Use GREENFIELD for a 15% storewide - Offer good for up to 2 orders per customer. Excludes orders over 40 lbs, sale items, volume discounts, and gift certificates.

-Salmon roe

-Fred Provenza's book Nourishment

-Fiber and Colon Health On A Well-Formulated Ketogenic Diet: New Insights Question Its Role As An Unconditional Requirement

-The Kettle & Fire bone broth Ben drinks - Use code GREENFIELD for 10% off

Additional resources/research from Dr. Paul Saladino: -Curcumin Curcumin (No RCTs which show benefit, potential toxicity) "The Dark Side of Curcumin" -Piperine Curcuminoids inhibit multiple human cytochromes P450 (CYP), UDP- glucuronosyltransferase (UGT), and sulfotransferase (SULT) enzymes, while piperine is a relatively selective CYP3A4 inhibitor

Impairment of UDP-glucose dehydrogenase and glucuronidation activities in liver and small intestine of rat and guinea pig in vitro by piperine

Plant pesticides (claustogenicity of safrole[also in black pepper], caffeic acid, chlorogenic acid, glucosinolates [sulforaphane precursors]) -Cyanogenic glycosides in food Cyanogenic glycosides in plant-based foods available in New Zealand

A Review of Cyanogenic Glycosides in Edible Plants

No association with meat consumption and colorectal cancer in Asia No association of saturated fat and animal protein with colorectal cancer -Fiber -Diverticulosis study (worsened with increased fiber) Low fiber no association with constipation, diverticulosis Removal leads to improvement in constipation Lack of benefit in adenoma recurrence Soluble fiber increases colon cancer in rodents Fiber does not increase alpha diversity -BHB and signalling/anti-aging mechanisms: Anti-Oxidant and Anti-Inflammatory Activity of Ketogenic Diet: New Perspectives for Neuroprotection in Alzheimer's Disease

Ketone bodies as signaling metabolites

β-hydroxybutyrate: Much more than a metabolite

D-ß-hydroxybutyrate: an anti-aging ketone body

Estrogenic properties of quercetin Effects of phyto-oestrogen quercetin on productive performance, hormones, reproductive organs and apoptotic genes in laying hens Dangers of excess omega-6 (especially from seed oils) Centenarians and genetic advantage Salicylates (coconut) Removal of flavonoid containing foods results in improved markers of oxidative stress Green Tea catechins at obtainable dosing connected with liver injury (rise in transaminases) Oxalate toxicity -Casomorphin: A naturally occurring opioid peptide from cow's milk, beta-casomorphine-7, is a direct histamine releaser in man -Methionine/glycine ratio: Effect of dietary glycine on methionine metabolism in rats fed a high-methionine diet

Methionine restriction decreases mitochondrial oxygen radical generation and leak as well as oxidative damage to mitochondrial DNA and proteins

Methionine and choline regulate the metabolic phenotype of a ketogenic diet

-Ketogenic Diet Improves Lifespan:

Epigenetic mechanisms underlying lifespan and age-related effects of dietary restriction and the ketogenic diet

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice

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Do you have questions, thoughts or feedback for Paul or me? Leave your comments below and one of us will reply!

See omnystudio.com/listener for privacy information.

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21 Kesä 202555min

This Guy Takes 75+ Supplements A Day & Does The Most Advanced AI Diagnostic Imaging For Health (& Wrote A Guide On How He Does It All!) With Dr. Peter Diamandis

This Guy Takes 75+ Supplements A Day & Does The Most Advanced AI Diagnostic Imaging For Health (& Wrote A Guide On How He Does It All!) With Dr. Peter Diamandis

Dr. Peter Diamandis first joined me, along with guest Tony Robbins, for the show: “Tony Robbins, Peter Diamandis & Ben Greenfield Reveal New Anti-Aging Biohacks & Breakthroughs in Precision Medicine You’ve Never Heard Of Before.” Today, the physician, investor, entrepreneur, and longevity enthusiast is back to reveal the secrets from his brand new book, Longevity Guidebook: How to Slow, Stop, and Reverse Aging—and NOT Die from Something Stupid, which includes tactics such as: Implementing proven lifestyle practices to optimize your diet, sleep, exercise, and mindset, all enabling extended healthspan. Understanding advancements in diagnostic and therapeutic technologies to find and reverse disease at the earliest time possible. Receiving insights on how to “NOT die from something stupid” and the breakthroughs that can save your life and the lives of those you love. Maximizing female healthspan through every stage of life. Building and maintaining a “longevity mindset” (coupled with the routines that will transform your health). You'll also get to explore what truly correlates with heart disease (the answer may surprise you), why your genes might matter less than you think, and the practical steps Dr. Diamandis personally takes to optimize muscle, metabolism, and sleep well into his 60s. From the impact of GLP-1s and the real story on alcohol's effect on longevity, to biohacks for sleep and the promise (and practical realities) of advanced diagnostics like full-body MRI and AI-powered heart scans—nothing is off the table. Whether you’re a health tech enthusiast, longevity nerd, or just curious about actionable strategies to dramatically extend your healthspan, this episode is packed with groundbreaking science, inspiring personal stories, and a glimpse into the future of human potential. Full show notes: https://bengreenfieldlife.com/longevityguide Episode Sponsors: CAROL Bike: The science is clear—CAROL Bike is your ticket to a healthier, more vibrant life. And for a limited time, you can get $100 off yours with the code BEN. Don't wait any longer, join over 25,000 riders and visit carolbike.com/ben today. Organifi Shilajit Gummies: Harness the ancient power of pure Himalayan shilajit anytime you want with these convenient and tasty gummies. Get them now for 20% off at organifi.com/Ben. LVLUP Health: Head over to lvluphealth.com/BGL and use code BEN15 for a special discount on their game-changing range of products. MOSH: MOSH's signature blend offers a plant-based high-protein bar. They are a great source of vitamin D and an excellent source of vitamin B12. Head to moshlife.com/BEN to save 20% off, plus FREE shipping on either the Best Sellers Trial Pack or the new Plant-Based Trial Pack. Pique: Go to Piquelife.com/Ben to get 20% off for life, plus a free starter kit with a rechargeable frother and glass beaker to elevate your ritual.See omnystudio.com/listener for privacy information.

19 Kesä 20251h 10min

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