Beyond 23&Me: A Deep Dive Into Ben Greenfield's Personal DNA Results (& How To Get Your Own Genes Interpreted).
Boundless Life13 Kesä 2019

Beyond 23&Me: A Deep Dive Into Ben Greenfield's Personal DNA Results (& How To Get Your Own Genes Interpreted).

I'm constantly blown away by the amount of genetic data and actionable information one can garner from a simple bit of saliva.

In today's episode, you're going to get an insider glimpse into how to go way beyond something as simple as 23AndMe or Ancestry and instead learn how to get truly useful health information that you can use to enhance health, performance, sleep, gut function, neurotransmitters and cognition and much more.

My guest on this podcast, Dr. Mansoor Mohammed, has an extremely impressive background in the field of genetics.

His credentials include:

-BSc. Specialized Honours in Molecular Genetics | University of Guelph | Guelph -Doctor of Philosophy with Distinction in Molecular Genetics & Immunology | University of Guelph | Guelph -Postdoctoral Clinical Cytogenetics Fellowship | University of California | Los Angeles -Postdoctoral Clinical Cytogenetics Fellowship | Baylor College of Medicine | Houston

Dr. Mansoor is now the President and CSO of The DNA Company, a leading and innovative provider of comprehensive Functional Genomics testing and consulting and an industry first: individually customized supplements based on your genetics. He is widely regarded as a pioneer in medical genomics and has been the recipient of multiple academic and industry awards. He is the holder of several patents in the general fields of molecular diagnostics and genomics research and is one of the most sought-after national and international conference speakers in the genre of personalized medicine.

Prior to his role at The DNA Company, Dr. Mansoor was:

- Founder and President of ManaGene (2010-2018)

- CEO of Combimatrix (Nasdaq traded leader in diagnostic genomic microarrays) (2006-2010)

- Director of Genomics at Quest Diagnostics (The world’s largest reference laboratory with a market capitalization of over $10 billion US) (2003-2006)

- Director of Research and Development at Spectral Genomics (one of the industry’s first commercial genomic microarray developers spun out of Baylor College of Medicine under Dr. Mansoor’s scientific leadership)

Dr. Mansoor maintains an active clinical practice as a genomics consultant to some of the leading executive health clinics in Canada and abroad.

During our discussion, you'll discover: -What makes each DNA test different and how to choose what's right for you...9:30
  • Consider the various elements of genetic testing:
    • SNPs (pronounce "snips"; single nucleotide polymorphisms)
    • Copy number variation (CNV)
    • INDEL (insertion/deletion polymorphism)
  • Understand how the various labs go about testing the elements
  • Humans have two identical copies of the DNA code (from each parent)
  • When testing for SNPs, the genetic paragraph is "read" and looks for variations between the two
  • The more paragraphs you try to query simultaneously, the greater risk of error (false negatives/positives)
  • Characteristics of a proper DNA test:
    • Concern is for the physical manifestation of the genes, not the genes themselves
    • Cellular function is key indicator
    • Identify the genes that influence the desired outcome
    • Pinpoint the specific DNA to test vs. "shotgun" approach
    • Avoid drawing data for data's sake
-A review of Ben's DNA test and how they compare to his two sons...25:00
  • Two different reports: Genome Pulse Report and Hormone Pulse Report (looking at the GPR)
  • Vascular function
    • Cells that line the vascular system receive the most wear and tear
    • 9P21 markers (not genes) are correlated with the lining of the blood vessels; "the heart of the human genome"
    • A alleles and G alleles
    • The more G alleles you have, the less resilient is the endothelial lining
    • Increase good quality vegetable matter
    • People with multiple G alleles benefit less from vegetable matter (like red wine) than those with none
    • Smokers are more likely to die of vascular disease than lung disease
    • Glutathione S-Transferase (GST) pathway is one of the key pathways in the body
    • Glutathionization: the cellular process that neutralizes toxins in the body
  • What happens when someone doesn't have 2 copies of a gene...
    • You sometimes have genes you didn't inherit from either parent
    • Talking about SNPs in the gene is irrelevant;
    • As is epigenetics (alter the expression of the genes, not the genes itself)
  • 3 vitally important GST genes:
    • Theta 1,
    • Pai 1,
    • Nu1
  • Should a person only have 1 copy of a gene, they will produce 50% less than someone with 2 copies
  • Ben Greenfield has 1 copy of the GSTT1 gene (as does 60% of the population)
    • Important to not exceed a healthy toxicity threshold
  • Ben Greenfield does not have the GSTM1 gene at all
    • Useless to discuss SNPs for that gene
    • The M1 gene is a backup: it can be lost with less consequence than other genes (such as the T1)
  • What this means is that Ben Greenfield has low to average glutathione detox capacity
    • Must be more cognizant of diet, environment, etc.
  • Ben's two boys are missing the GSTT1 gene completely
-Personalizing diet and/or supplements based on DNA test results...57:25
  • Youtrients [link]
  • Nothing compares to an optimal diet (eating whole foods)
  • Customized based on dietary limitations (lactose intolerance)
  • Ethnic and geographic factors, as well as the environment during weaning, affect how to interpret test results
  • Elites of Victorian era England adjusted their lifestyle (living in Scottish highlands in the autumn months)
  • Reduce, not promote, supplementation, to where only necessary
  • Our bodies are not designed to accommodate many of the supplements on the market
  • "Is there a cellular function that is dysfunctional?" Then address that through supplementation
  • More is not always better when it comes to genetics
  • 3 disparate aspects of cellular function:
    • Endothelial quality
    • Detox capacity
    • Insulin productivity and function in response to diet
-Differences between the hormone pulse report and the genome pulse report...1:18:25
  • BDNF (brain-derived neurotropic factor) is one of the most important genes in our body
  • First thing looking at: How does the body (male or female) convert progesterones into androgens, into estrogens
  • t-intersection (4 points):
    • How efficiently converting progesterone into androgens
  • 3 things happen when you make testosterone:
    • Use it
    • Convert some of it into DHT
    • Metabolize (glucuronidation)
  • Ben has the perfect balance of the t-intersection
  • Ben's boys are identical, except have a higher predisposed conversion of testosterone into estrogen
-About the ACTN3 gene and its relation to exercise types...1:28:50 -And much more... Resources from this episode:

- Click here for testing with Youtrients through the TheDNACompany. They offer their complete functional genomics test package for $399 USD (that’s a savings of $50 from retail price), and your test package includes both Hormone and Genome Pulse panel tests as well as a clinical report for each panel, along with full access to their webinar series, which introduces the science and interpretation of your genomic results with regards to key biological systems and processes. Click here for that special offer from YouTrients for Ben Greenfield listeners.

- Ben's Hormone Pulse results from TheDNA Company [pdf-embedder url="/wp-content/uploads/2019/06/Ben-Greenfield-HORMONE-PULSE-REPORT.pdf" title="Ben Greenfield HORMONE PULSE REPORT"]

- Ben's Genome Pulse results from TheDNA Company [pdf-embedder url="/wp-content/uploads/2019/06/Ben-Greenfield-GENOME-PULSE-REPORT.pdf" title="Ben Greenfield GENOME PULSE REPORT"]

Episode sponsors:

-Kion: My personal playground for new supplement formulations. Ben Greenfield Fitness listeners receive a 10% discount off your entire order when you use discount code: BGF10.

-Trusii: Contains a host of anti-inflammatory, anti-obesity, and anti-allergy benefits. For this reason, I have decided to now make consumption of hydrogen-rich water an important part of my daily nutritional routine...and I highly recommend it! Enter code: BEN at checkout and get 30% off your order!

-Halo Sport: Halo Sport revolutionized physical training by being the first-ever product that can increase your neuroplasticity by putting your brain into a state that neuroscientists called hyperlearning. The fully upgraded Halo Sport 2 was just announced and it’s pre-selling for just $279 (less than half the price of the first model) when you use code: GREENFIELD.

-Birdwell Beach Britches: Quality is our Gimmick isn’t just our slogan, it’s a commitment we honor with every stitch we sew. 100% money back guarantee. Get 10% off your order, PLUS free shipping on any order over $99 when you use discount code: BENG.

Do you have questions, thoughts or feedback for Dr. Mansoor or me? Leave your comments below and one of us will reply!

See omnystudio.com/listener for privacy information.

Jaksot(1747)

Foilboarding Mastery, Hidden Monopoly Secrets, Digital Addiction & How To Make Family Dinners Fun Again, With Exploding Kitten's Elan Lee.

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In this episode with Elan Lee, you’ll get a behind-the-scenes look at one of the most creative minds in the world of game design—and walk away with some unexpected life lessons along the way. You’ll hear how Elan went from crafting movie special effects and pioneering the Xbox to co-creating Exploding Kittens, a wildly successful card game that started with nothing more than a Sharpie and a deck of poker cards on a beach in Hawaii. Whether you’re a parent looking for better ways to connect with your kids, a creative chasing your next big idea, or just someone who loves a good origin story with a dose of humor and heart, you won't want to miss this conversation. Full show notes: https://bengreenfieldlife.com/elanlee Episode Sponsors: RoXiva: Experience the world-class RX1 lamp—an immersive, multisensory tool designed to transport you into deeper, expanded states of awareness through meticulously crafted light and sound journeys. Get yours now by going to roXiva.com/ben! Calroy: Head on over to calroy.com/ben and save over $50 when you purchase the Vascanox (a breakthrough product providing nitric oxide support for up to 24 hours with a single dose) and Arterosil (a premier supplement to support the endothelial glycocalyx—the fragile inner lining of the entire vascular system) bundle at calroy.com/ben. Plus, you'll receive a free canister of 2-in-1 Nitric Oxide Test Strips with a 3-pack bundle purchase. LeelaQ: Not only do LeelaQ’s products neutralize EMFs, increase ATP production, optimize HRV, and improve blood flow, but they've been third-party proven to do so in placebo-controlled double-blind studies. Visit leelaq.com/ben and use code BEN10 for 10% off. Ketone-IQ: Ketones are a uniquely powerful macronutrient that can cross the blood-brain barrier and increase brain energy and efficiency. With a daily dose of Ketone-IQ, you'll notice a radical boost in focus, endurance, and performance. Save 30% off your first subscription order of Ketone-IQ at Ketone.com/BENG. Prolon: Prolon's 5-Day Fasting Nutrition Program is scientifically tested and patented to nourish your body while keeping it in a physiological fasted state. Right now, you can save 15% on your 5-day nutrition program when you go to prolonlife.com/GREENFIELD.See omnystudio.com/listener for privacy information.

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12 Kesä 20251h

The Longevity City Of The Future, The Ultimate Biohacking Wellness Club Experience & The Next-Level Merging Of Ancient Wisdom & Modern Science, With Tim Gurner

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In this fascinating episode, you’ll get to explore the story behind Saint Haven Private Club—an exclusive wellness club redefining what it means to live well, recover deeply, and connect meaningfully. I sit down with my friend Tim Gurner —founder of GURNER™, visionary developer, and global wellness pioneer—for a raw, eye-opening conversation about performance, resilience, and what it really takes to create spaces that heal, inspire, and transform. If you’re curious about the future of wellness, performance, and human potential, you won't want to miss this show. Full show notes: https://bengreenfieldlife.com/timgurner AND... If you’re in Melbourne and serious about taking your health to the next level, I want to personally invite you to join me for a rare live appearance. I’ll be delivering a deep-dive session on how to hack your biology, dial in your performance, and radically extend your healthspan—using the very same tactics and tools I’ve tested on myself and my clients for years. This is not your average wellness seminar. We’re talking about a two-hour immersive event filled with real science, practical tools, and an opportunity to connect with a community of people who, like you, are looking to break free from average and live at the edge of human potential. Here are the details: 📍Venue: Luminaire, Corner of Browns Lane & York Street, South Melbourne VIC 3205 📅 Date: June 26th, 6:30 p.m. – 8:30 p.m. 🎟️ General Admission – $180 AUDIncludes access to the main event + nourishing wholefoods catering curated to support metabolic flexibility, brain clarity, and digestive health. Limited to 200 spots. 🎟️ VIP Experience – $350 AUDIncludes everything above, plus: An exclusive post-session meet-and-greet with me A Saint Haven goodie bag packed with my personally approved supplements and wellness tools Extra Q&A time and private networking with Australia’s top health disruptors Only 50 VIP spots are available This event will fill fast. If you’ve been waiting for a moment to reset your health trajectory—or simply want to learn how to upgrade your biology using tools that actually work—this will be a night worth showing up for. I can’t wait to see you there! For early access to tickets and event info for the June 26th public event, you can head here: Saint Haven Presents Ben Greenfield. Episode Sponsors: Organifi Shilajit Gummies: Harness the ancient power of pure Himalayan shilajit anytime you want with these convenient and tasty gummies. Get them now for 20% off at organifi.com/Ben. Chroma SkyPortal 2.1: If you’re serious about dialing in your desk light for both performance and sleep, check out the SkyPortal 2.1 at getchroma.co and use code BENGREENFIELD to save 10% on your order. Ketone-IQ: Ketones are a uniquely powerful macronutrient that can cross the blood-brain barrier and increase brain energy and efficiency. With a daily dose of Ketone-IQ, you'll notice a radical boost in focus, endurance, and performance. Save 30% off your first subscription order of Ketone-IQ at Ketone.com/BENG. MUD\WTR: Not only does MUD\WTR give you that morning boost you need, but it’s also packed with adaptogens, antioxidants, and is 100% USDA-certified organic, non-GMO, gluten-free, vegan, and kosher. Give MUD\WTR a shot and save up to 43% off your entire order, receive free shipping, and get a free rechargeable frother by going to mudwtr.com/bengreenfield. Hiya: Give your kids the full-body nourishment they need to grow into healthy adults. I’ve secured a special deal with Hiya on their best-selling children's vitamin—get 50% off your first order today! To claim this deal, you must go to hiyahealth.com/BEN (it is not available on their regular website).See omnystudio.com/listener for privacy information.

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In today’s episode, I sit down with returning guest Dr. Scott Sherr, a board-certified internal medicine physician known for his work in hyperbaric medicine, innovative nootropics, and his role as Chief Operating Officer of Troscriptions, where he developed the infamous precision-dosed “smurf mouth” methylene blue troches (use code BEN to save 10%). In this conversation, we dive into the science and potential of one of the most intriguing compounds in advanced wellness: cordycepin. Dr. Scott Sherr is a Board-Certified Internal Medicine Physician Certified to Practice Health Optimization Medicine (HOMe), a specialist in Hyperbaric Oxygen Therapy (HBOT), and COO of Troscriptions. His clinical telepractice includes HOMe as its foundation alongside an integrative approach to HBOT that includes cutting-edge and dynamic HBOT protocols, comprehensive testing (using the HOMe framework), targeted supplementation, personal practices, synergistic technologies (new, ancient, psychedelic), and more. Full show notes: https://bengreenfieldlife.com/sherr Episode Sponsors: Just Thrive: For a limited time, you can save 20% off a 90-day bottle of Just Thrive Probiotic and Just Calm at justthrivehealth.com/ben with promo code BEN. That’s like getting a month for FREE—take control today with Just Thrive! LVLUP Health: I trust and recommend LVLUP Health for your peptide needs as they third-party test every single batch of their peptides to ensure you’re getting exactly what you pay for and the results you’re after! Head over to lvluphealth.com/BGL and use code BEN15 for a special discount on their game-changing range of products. Calroy: Head on over to calroy.com/ben and save over $50 when you purchase the Vascanox (a breakthrough product providing nitric oxide support for up to 24 hours with a single dose) and Arterosil (a premier supplement to support the endothelial glycocalyx—the fragile inner lining of the entire vascular system) bundle at calroy.com/ben. Plus, you'll receive a free canister of 2-in-1 Nitric Oxide Test Strips with a 3-pack bundle purchase. Sunlighten: Discover the ultimate efficiency in wellness with the Sunlighten Solo System, a compact, portable far infrared sauna designed to detoxify, reduce stress, improve sleep, and enhance heart health—all while fitting seamlessly into your daily routine. Save $600 or more today and start biohacking your mind, body, and spirit at get.sunlighten.com/ben! BIOptimizers Mushroom Breakthrough: Mushroom Breakthrough combines four powerful mushrooms with collagen to enhance brain function, promote healthier skin, hair, and nails, and strengthen your immune system. Go to bioptimizers.com/ben now and enter promo code BEN10 to get 10% off any order.See omnystudio.com/listener for privacy information.

5 Kesä 202555min

What Cookware Does Ben Use?, Do You REALLY Need To Avoid Gluten & How To Gain Muscle Fast: Solosode #489

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31 Touko 202549min

The #1 Daily Habit That Changed Ben Greenfield’s Family Forever (& It’s Not a Biohack or Supplement!)

The #1 Daily Habit That Changed Ben Greenfield’s Family Forever (& It’s Not a Biohack or Supplement!)

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29 Touko 20251h 28min

What Porn Does To Your Brain (& What To Do About It)—How To Use Proven Science To QUIT Porn For Good, With Dr. Trish Leigh.

What Porn Does To Your Brain (& What To Do About It)—How To Use Proven Science To QUIT Porn For Good, With Dr. Trish Leigh.

In this episode with the remarkable Dr. Trish Leigh, a renowned cognitive neuroscientist and addiction recovery expert, you'll get to dive into the neuroscience of pornography and its far-reaching effects on the brain, hormones, relationships, and overall well-being. If you’re looking to unlock greater focus, happiness, and intimacy—or want to help someone you care about—this episode brings neuroscience and practical wisdom together in a conversation you won’t want to miss. Full show notes: https://bengreenfieldlife.com/mindovermatter Episode Sponsors: Calroy: Head on over to calroy.com/ben and save over $50 when you purchase the Vascanox (a breakthrough product providing nitric oxide support for up to 24 hours with a single dose) and Arterosil (a premier supplement to support the endothelial glycocalyx—the fragile inner lining of the entire vascular system) bundle at calroy.com/ben. Plus, you'll receive a free canister of 2-in-1 Nitric Oxide Test Strips with a 3-pack bundle purchase. Ancient Crunch: Introducing the best guilt-free snack on the market: classic, seed oil free tortilla chips with only 3 natural ingredients. Go to masachips.com/greenfield and get 25% off your first order! BON CHARGE: BON CHARGE is a holistic wellness brand with a wide range of products that naturally address the issues of modern life. Their products can help you sleep better, perform better, recover faster, balance hormones, reduce inflammation, and so much more. Go to boncharge.com/GREENFIELD and use coupon code GREENFIELD to save 15%. Truvaga: Balance your nervous system naturally with Truvaga's vagus nerve stimulator. Visit Truvaga.com/Greenfield and use code GREENFIELD30 to save $30 off any Truvaga device. Calm your mind, focus better, and recover faster in just two minutes. LMNT: Everyone needs electrolytes, especially those on low-carb diets, who practice intermittent or extended fasting, are physically active, or sweat a lot. Go to DrinkLMNT.com/BenGreenfield to get a free gift with your purchase! Sunlighten: Discover the ultimate efficiency in wellness with the Sunlighten Solo System, a compact, portable far infrared sauna designed to detoxify, reduce stress, improve sleep, and enhance heart health—all while fitting seamlessly into your daily routine. Save $600 or more today and start biohacking your mind, body, and spirit at get.sunlighten.com/ben!See omnystudio.com/listener for privacy information.

24 Touko 20251h 5min

Could This ONE Simple Change Fix Your Sleep Forever?, Making Schools Healthy Again, and Why Your Air Filter Probably DOESN'T Work Right With Mike Feldstein

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