The Weight-Loss Drug Revolution, Part 1: Why These Drugs Work So Well

The Weight-Loss Drug Revolution, Part 1: Why These Drugs Work So Well

Today’s podcast is about the weight-loss drug revolution—which I believe might be one of the most important stories in the world right now. Despite all the attention weight-loss drugs are receiving, it’s possible that they might soon affect the world even more than we realize as they teach us about the science of human metabolism, decision-making, and even free will. Beverly Tchang, an endocrinologist at Weill Cornell, explains how these drugs work, what they mean for people with diabetes and obesity, and how to wrap our minds around their stranger and spookier side effects. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guest: Beverly Tchang Producer: Devon Manze Learn more about your ad choices. Visit podcastchoices.com/adchoices

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Why the Bad Guys—in China, Russia, Iran, and the U.S.—Are Having a Terrible Winter

Why the Bad Guys—in China, Russia, Iran, and the U.S.—Are Having a Terrible Winter

One year ago, we had Anne Applebaum on the podcast to talk about her essay, "The Bad Guys Are Winning." And I think you could have made an argument that this was the most important story in geopolitic...

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Why America is Suffering a 'Friendship Recession'

Why America is Suffering a 'Friendship Recession'

Americans have never spent so much time alone. And alone time is rising sharply for every demographic—young and old, male and female, white and non-white, metro and rural. But is aloneness the same as...

29 Marras 202259min

Thanksgiving Mega-Pod: Bob Iger’s Power Grab, SBF’s Scandal, and Elon Musk’s Omnishambles

Thanksgiving Mega-Pod: Bob Iger’s Power Grab, SBF’s Scandal, and Elon Musk’s Omnishambles

Today’s episode is a Thanksgiving feast of corporate scandal and media gossip. Derek kicks things off with a big-picture theory for why everything in tech and media seems to be falling apart at the sa...

22 Marras 20221h 26min

If China Invades Taiwan, Is It World War III?

If China Invades Taiwan, Is It World War III?

Today’s episode is about China’s turn toward authoritarianism—and why it might be one of the most important stories in the world. If you don’t know a lot about China—if you’ve been interested or aston...

18 Marras 202248min

A Crypto Catastrophe: The Stunning Fall of FTX—and What Comes Next

A Crypto Catastrophe: The Stunning Fall of FTX—and What Comes Next

Derek shares his thoughts on the meltdown of crypto exchange FTX and the disgrace of its founder, Sam Bankman-Fried, before welcoming veteran finance journalist William D. Cohan to discuss the history...

15 Marras 202247min

Instant Reaction Pod: Midterm Election Winners, Losers, Surprises, and Takeaways

Instant Reaction Pod: Midterm Election Winners, Losers, Surprises, and Takeaways

The polls were right; the vibes were wrong. Democrats seem to have blocked the Republican wave by riding “Dobbs and democracy.” Trump lost, and extremism lost. DeSantis won, and Florida is a red state...

9 Marras 202217min

Elon Musk's Reign of Chaos and Mark Zuckerberg's Metaverse Madness

Elon Musk's Reign of Chaos and Mark Zuckerberg's Metaverse Madness

The Musk regime is off to a chaotic start at Twitter. In barely a week or two of ownership, Elon has already overseen a collapse in advertising revenue, announced a pivot to subscriptions, attempted t...

7 Marras 202248min

America in the Age of Conspiracy: Q-Anon, JFK, Aliens, and More

America in the Age of Conspiracy: Q-Anon, JFK, Aliens, and More

Americans are unusually conspiratorial as a nation. But in the last week, we have really outdone ourselves. The beating of Paul Pelosi—husband of the Speaker of the House—by a Q-Anon conspiracy theori...

4 Marras 20221h 2min

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