#72 IGF-1, mTOR, Autophagy Deep Dive
Siim Land Podcast14 Syys 2018

#72 IGF-1, mTOR, Autophagy Deep Dive

You must've heard that eating protein, meat, and dairy gives you heart disease and gives you cancer. Does elevating IGF-1 and mTOR accelerate aging or do low levels of IGF-1 actually make you more prone to neurodegeneration and shorter life? Is it better to bulk up fast with carbs or do it slowly on keto? Does bulletproof coffee stop autophagy? How many carbs to eat on the targeted ketogenic diet? These are some of the few questions of this Body Mind Empowerment podcast. I’m your host Siim Land and we’re gonna have another Q & A episode. This time I decided to focus primarily on these anabolic pathways like mTOR or mammalian target of rapamycin and how it affects your longevity. mTOR and IGF-1 make you anabolic and grow but for longevity, you want to know how to balance it with things like autophagy and AMPK. So, most of the questions will be about these topics. Let’s get to it. Timestamps: Are IGF-1 and mTOR Bad for You 02:06 Autophagy and mTOR Explained 12:53 Does Bulletproof Coffee Stop Autophagy 29:30 Bulking on Carbs VS Bulking on Keto 37:00 How Many Carbs on Targeted Ketogenic Diet 44:14 What is Carb Backloading 48:17 And Much More... Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox Download mp3 If you want to support this podcast, then I'd greatly appreciate if you could join my Patreon community. You'll be able to get access to unique worksheets about Body Mind Empowerment, a lot of exclusive videos about my routines, biohacking workshops, and a privilege for your questions on the next Q&A. Click Here to Support the Show on Patreon! Show Notes Article on Is IGF-1 Good or Bad? Article on Balancing mTOR and Autophagy Article on Mastering mTOR for Longevity Article on Bulletproof Coffee and Autophagy Video on Autophagy and mTOR Video on How I Balance Autophagy and mTOR with Fasting Watch the Biohacker Summit Tallinn Livestream Watch the Biohacking Bootcamp Videos on Patreon Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program P.S. If you want to keep yourself on point with your recovery and sleep, then consider getting the OURA ring sleep monitoring ring. They're coming out with the 2.0 upgraded version and you can get a 10% discount by using the code SIIMLAND at checkout. Stay Empowered Siim

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#438 Skin Anti-Aging Masterclass with Dr Alexis Ortega

#438 Skin Anti-Aging Masterclass with Dr Alexis Ortega

Get Bon Charge infrared sauna blanket 15% off: https://boncharge.com/pages/siimland Timestamps: 00:00 Intro 00:30 Why Skin Anti-Aging Matters 02:15 What Everyone Should Do for Skin Anti-Aging 06:25 Bon Charge Sponsorship 07:12 Skin Aging Analysis Techniques 12:15 Pores and Cleaning the Skin 15:25 Three Basic Products Alexis Gives His Patients 20:55 Best Sunscreens to Take 37:30 Retinol 48:15 Microneedling 53:05 Red Light Therapy and Lasers 01:02:35 Botox 01:08:35 Exosomes 01:14:15 Moisturizers 01:17:40 Copper Peptide GHK-Cu 01:23:00 Niacinamide 01:24:55 Skin anti-aging supplements 01:34:55 Final words Alexis Ortega MD Instagram: https://www.instagram.com/alexis_ortega_md/

1 Helmi 1h 37min

#436 Is Methylene Blue the Magic Bullet for Health? - Dr Scott Sherr

#436 Is Methylene Blue the Magic Bullet for Health? - Dr Scott Sherr

Get Bon Charge infrared sauna blanket 15% off: https://boncharge.com/pages/siimland Timestamps: 00:00 Introduction 00:30 What Is Methylene Blue 05:35 Methylene Blue Antiviral Effects 12:55 Methylene Blue Effects on Mitochondrial Function 17:55 Is Methylene Blue and Oxygen 24:30 Methylene Blue for Exercise 26:10 Nitric Oxide 31:25 Does Methylene Blue Have Longevity Benefits 39:50 Skin Anti-Aging Effects 43:30 Safety 48:50 Nootropic Effects 52:05 Right Dosage Dr Scott Sherr Instagram: https://www.instagram.com/drscottsherr/

18 Tammi 59min

#435 Hormone Doc Amy Killen Reveals the TRUTH About TRT and HRT Safety

#435 Hormone Doc Amy Killen Reveals the TRUTH About TRT and HRT Safety

Order my new book: https://www.amazon.com/dp/B0CW1B2XM1 Timestamps: 00:30 Is Hormone Replacement Therapy Good or Bad for You 05:22 Benefits of Treating Aging Hormones 08:20 Cardioprotective Effects of Estrogen 12:00 Estrogen’s Benefits in Men 16:15 How to Track Your Hormones 17:20 Testosterone Decline with Age 21:20 What’s Considered Low Testosterone 25:17 What Age to Start TRT 27:28 Testosterone Therapy for Women 28:42 Risks with TRT 32:13 Can You Extend Your Reproductive Window 36:38 DHEA and DHT 38:13 Progesterone and Pregnenolone 41:03 Different Forms of Testosterone 43:57 Where to Start With Hormone Optimization 46:12 Peptides for Testosterone and Estrogen 48:32 Growth Hormone 52:27 Gene Therapy for Preventing Aging Amy Killen Instagram: https://www.instagram.com/dr.amybkillen/

11 Tammi 54min

#434 Longevity Doctor Reveals How Genetics Affect Your Longevity

#434 Longevity Doctor Reveals How Genetics Affect Your Longevity

Get Bon Charge infrared sauna blanket 15% off: https://boncharge.com/pages/siimland Timestamps: 00:30 What Is Precision Medicine 05:15 N=1 vs Fundamentals 12:10 The Longevity Equation 16:12 Bon Charge Sponsorship 17:02 How Precision Medicine Works 22:40 Can You Excrete Microplastics 28:55 How Frequently Should You Test Things 31:20 Stem cells 37:25 Cancer risk 46:40 Stem cells for autoimmunity 51:05 Heart disease risk 01:01:50 Neurodegeneration risk 01:06:15 Individual response to diet and exercise Dr Anil Bajnath Instagram: https://www.instagram.com/dranilbajnath/ Order my new book: https://www.amazon.com/dp/B0CW1B2XM1

3 Tammi 1h 18min

#433 SUPERPODCAST of Protocols for Diet, Exercise, Sleep, and Supplements

#433 SUPERPODCAST of Protocols for Diet, Exercise, Sleep, and Supplements

Timestamps: 00:00 Intro 00:40 My Evidence-Based Nutrition 17:20 Gil Carvalho on Understanding Health Information 01:01:28 Michael Lustgarten on Nutrition and Bloodmarkers 01:43:38 My Evidence-Based Workout Plan 01:59:25 Dave Pascoe Exercise Routine 02:13:50 My Evidence-Based Sleep Routine 02:26:20 My Evidence-Based Morning Routine 02:38:20 Top Evidence-Based Longevity Supplements 02:45:00 Dr Bill Harriss on Omega-3s 03:12:30 Dr Alexis Ortega on His Supplements

28 Joulu 20243h 25min

#432 Top Foods and Supplements for Brain Health, Top 10 Health Items, and More - Q&A

#432 Top Foods and Supplements for Brain Health, Top 10 Health Items, and More - Q&A

Bon Charge holiday sale for 25% off: https://boncharge.com/pages/siimland Timestamps: 00:00 Top Foods and Supplements for Brain Health 07:07 Best and Worst Longevity Advice I've Received 12:45 Bon Charge Red Light Therapy Sponsorship 13:36 Top 3 Spices 16:12 How I Can Eat 3500 Calories When Doing Intermittent Fasting 19:23 Top 10 Health Purchases/Item 31:38 Daily Melatonin Dose 32:23 My Favorite Food 35:54 How to Approach Bloodwork Order my new book: https://www.amazon.com/dp/B0CW1B2XM1

20 Joulu 202445min

#431 The Second Most Important Muscle In Your Body and How to Train It - Marc Hamilton PhD

#431 The Second Most Important Muscle In Your Body and How to Train It - Marc Hamilton PhD

Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland Timestamps: 00:00 Intro 01:20 Marc Hamilton’s Soleus Study 08:45 Why Muscles Don’t Burn That Many Calories 13:13 Bon Charge Sponsorship 14:03 What Is the Soleus Muscle 22:08 Soleus Pushup Tutorial 31:08 Why Just Exercise Isn’t the Solution 44:20 How Long to Do the Soleus Pushup 57:45 Learn More About Marc’s Work 01:02:50 Marc’s Realization About Muscle Metabolism Marc Hamilton's Soleus Pushup Tutorials: https://www.youtube.com/@UCFWtvrfRWSi0KUFW1ZWo5dg My video about soleus pushups: https://youtu.be/wSJClvkCznY Order my new book: https://www.amazon.com/dp/B0CW1B2XM1

13 Joulu 20241h 16min

#430 The Longevity Leap, Fitness, Nutrition, and Bloodwork w/ Dr Michael Lustgarten

#430 The Longevity Leap, Fitness, Nutrition, and Bloodwork w/ Dr Michael Lustgarten

YouTube video on Michael's channel: https://www.youtube.com/watch?v=qIloJSMZdAA&t=20s&pp=ygUUc2lpbSBsYW5kIGx1c3RnYXJ0ZW4%3D

8 Joulu 20241h 50min

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