Podcast #298: Seizures

Podcast #298: Seizures

Author: Sam Killian, M.D.

Educational Pearls

  • The availability of antiepileptic treatment has changed in the last 30 years.
  • A recent study in JAMA followed 18,000 pts with epilepsy for 30 years to assess the effectiveness of looked at seizure control.
  • The study found that although there have been new drugs introduced over the last 30 years, there has not been much of an improvement in seizure control.
  • Side effect profiles and medicine compliance may have improved in this time period, but the main goal of reducing seizure frequency has not been reached.

References: Chen Z, Brodie MJ, Liew D, Kwan P. Treatment Outcomes in Patients with Newly Diagnosed Epilepsy Treated With Established and New Antiepileptic DrugsA 30-Year Longitudinal Cohort Study. JAMA Neurol. Published online December 26, 2017. doi:10.1001/jamaneurol.2017.3949

Jaksot(1146)

Podcast # 367: Digital Necrosis after Epinephrine Drip

Podcast # 367: Digital Necrosis after Epinephrine Drip

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Podcast # 366: Ehlers Danlos

Podcast # 366: Ehlers Danlos

Podcast # 366: Ehlers Danlos Author: Gretchen Hinson, MD. Educational Pearls: Heritable mutation in collagen synthesis and expression commonly resulting in joint hyperextension and skin elasticity....

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Podcast # 365: Renal Trigger Point Injections

Podcast # 365: Renal Trigger Point Injections

Author: Erik Verzemnieks, MD Educational Pearls: Single study in Japan demonstrated possible effectiveness of renal colic trigger point Patients had injection at the area of maximal tenderness on...

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Podcast # 364: Other causes of ST elevation

Podcast # 364: Other causes of ST elevation

Author: Peter Bakes, MD Educational Pearls: Pericarditis, LBBB, LVH and left ventricular aneurysms can all present with ST elevation. Ventricular aneurysm will present days after a cardiac event ...

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Podcast # 363:  Ketamine for Alcohol Withdrawal

Podcast # 363: Ketamine for Alcohol Withdrawal

Educational Pearls: Recent study has shown adjunctive ketamine can be useful in setting of alcohol withdrawal. Ketamine was associated with a decrease in the amount of benzodiazepines needed, lik...

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Podcast # 362: Giant Hogweed

Podcast # 362: Giant Hogweed

Author: John Winkler, MD Educational Pearls: Tall flowering plant with phototoxic sap Direct skin contact with the sap can cause the skin to become photosensitive Severe blisters and even burns...

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Podcast # 361: Vertiginous Dizziness

Podcast # 361: Vertiginous Dizziness

Author: Peter Bakes, MD Educational Pearls: Important to find out if patients mean dysequilibrium, lightheadedness, or vertigo when patients say they are "dizzy." Differentiate central vs. periph...

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Podcast # 360: Epidural Abscess Screening

Podcast # 360: Epidural Abscess Screening

Author: Dylan Luyten, MD. Educational Pearls:   Dangerous causes of back pain: AAA, cauda equina syndrome, epidural abscess. Young person with back pain needs to be evaluated for injection drug use...

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