Podcast #298: Seizures

Podcast #298: Seizures

Author: Sam Killian, M.D.

Educational Pearls

  • The availability of antiepileptic treatment has changed in the last 30 years.
  • A recent study in JAMA followed 18,000 pts with epilepsy for 30 years to assess the effectiveness of looked at seizure control.
  • The study found that although there have been new drugs introduced over the last 30 years, there has not been much of an improvement in seizure control.
  • Side effect profiles and medicine compliance may have improved in this time period, but the main goal of reducing seizure frequency has not been reached.

References: Chen Z, Brodie MJ, Liew D, Kwan P. Treatment Outcomes in Patients with Newly Diagnosed Epilepsy Treated With Established and New Antiepileptic DrugsA 30-Year Longitudinal Cohort Study. JAMA Neurol. Published online December 26, 2017. doi:10.1001/jamaneurol.2017.3949

Jaksot(1146)

Podcast # 335: Blunt Head Trauma

Podcast # 335: Blunt Head Trauma

Author: Peter Bakes, M.D. Educational Pearls: Epidural hematomas have a characteristic convex appearance on CT while a subdural hematoma will have a concave appearance. Indications for operative ...

29 Touko 20188min

Podcast #334 - Resuscitative Thoracotomy

Podcast #334 - Resuscitative Thoracotomy

Author: Dylan Luyten, MD Educational Pearls: Resuscitative thoracotomies are most commonly used for treatment of cardiac tamponade and to selectively perfuse the brain and heart in setting of hemor...

25 Touko 20187min

Podcast #333 - TBI Prognosticators

Podcast #333 - TBI Prognosticators

Author: Michael Hunt, MD Educational Pearls: Studies have shown that patients with decreasing GCS scores have worse outcomes, however GCS of 4 has worse outcome than GCS 3. Alternative scoring sy...

23 Touko 20183min

Podcast #332 - Door To Furosemide Time

Podcast #332 - Door To Furosemide Time

Author: Nick Hatch, MD Educational Pearls: Recent study argues that CHF patients receiving furosemide within 60 minutes of arrival had a lower in-hospital mortality than those receiving it after (2...

21 Touko 20182min

Podcast # 331:  Oral Rehydration Therapy (ORT)

Podcast # 331: Oral Rehydration Therapy (ORT)

Author: Nick Hatch, MD Educational Pearls: The sodium-glucose cotransporter in the gut is essential for rehydration. Oral rehydration therapies require an equimolar concentration of glucose and s...

19 Touko 20184min

Podcast # 330:  Behcet Disease

Podcast # 330: Behcet Disease

Author: Nick Hatch, MD Educational Pearls: Behcet Disease is an autoimmune disease that can affect any organ system. Typical symptoms include recurrent oral and genital ulcers, but more concernin...

17 Touko 20184min

Podcast # 329:  Hypokalemic Periodic Paralysis

Podcast # 329: Hypokalemic Periodic Paralysis

Author: Dylan Luyten , MD Educational Pearls: Rare autosomal dominant condition that is often misdiagnosed as a psychiatric illness. Presents as profound muscle weakness with frank paralysis that...

15 Touko 20183min

Podcast # 328:  Sleep Deprivation

Podcast # 328: Sleep Deprivation

Author: Sam Killian, MD Educational Pearls: Insufficient sleep and disrupted circadian rhythms are a major health problem today Millions of dollars, thousands of deaths, and millions of injuri...

11 Touko 20185min

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