Podcast 529: Hemophilia

Podcast 529: Hemophilia

Contributor: Aaron Lessen, MD

Educational Pearls:

  • Hemophilia is characterized by bleeding (A /B) A is is 8, B (chrstmas, 9)
  • Hemophilia refers to a group of bleeding disorders caused by a deficiency in a certain clotting factor. The two most common are hemophilia A (caused by a lack of factor VIII), and B (caused by a lack of factor 9)
  • Most cases are inherited in an X-linked recessive manner. Therefore, males are the most commonly affected. However, spontaneous cases do occur in all sexes.
  • People with hemophilia can present to the ED with a variety of bleeding complications including hemarthrosis, intracranial hemorrhage, and GI bleeds.
  • Treatment is guided by the type of hemophilia and the degree of bleeding, with the most severe cases being treated with replacement of 100% of that person's deficient clotting factor.
  • Timely treatment improves outcomes, so consider empiric therapy in those with known hemophilia

References

Hemophilia A in the third millennium.Franchini M, Mannucci PM Blood Rev. 2013 Jul;27(4):179-84. Epub 2013 Jun 28.

Rheumatic manifestations of hematologic disorders.Aviña-Zubieta JA, Galindo-Rodriguez G, Lavalle C Curr Opin Rheumatol. 1998;10(1):86.

The molecular genetics of hemophilia: blood clotting factors VIII and IX.Lawn RM Cell. 1985;42(2):405.

Guidelines for the management of hemophilia.Srivastava A, Brewer AK, Mauser-Bunschoten EP, Key NS, Kitchen S, Llinas A, Ludlam CA, Mahlangu JN, Mulder K, Poon MC, Street A, Treatment Guidelines Working Group on Behalf of The World Federation Of Hemophilia Haemophilia. 2013 Jan;19(1):e1-47. Epub 2012 Jul 6.

Summarized by Will Dewispelaere, MS4 | Edited by Erik Verzemnieks, MD

Jaksot(1148)

Podcast 540:   Zyprexa

Podcast 540: Zyprexa

Contributor:  Don Stader, MD Educational Pearls: Olanzapine (Zyprexa) is an atypical antipsychotic that can be used in a similar fashion to haloperidol for pain and nausea, including that with abdomi...

11 Helmi 20202min

Podcast 539:  Coricidin Abuse

Podcast 539: Coricidin Abuse

Contributor:  Rachel Beham, PharmD Educational Pearls: Coricidin HBP Cough & Cold (dextromethorphan and chlorpheniramine) is one of the more commonly abused over-the-counter medications Dextromethorp...

10 Helmi 20203min

Podcast 538:  Low Maintenance Boxer's Fracture

Podcast 538: Low Maintenance Boxer's Fracture

Contributor: Jared Scott, MD Educational Pearls: A distal 5th metacarpal neck fracture is often referred to as a "boxer's fracture" and a common fracture encountered in the emergency department Splin...

4 Helmi 20202min

Podcast 537:  Thoughts on Cardiac Arrest

Podcast 537: Thoughts on Cardiac Arrest

Contributor:  Don Stader, MD Educational Pearls: High-quality compressions are an essential, and probably one of the most important, part of cardiac arrest  Actual evidence for drugs in cardiac arres...

3 Helmi 20205min

UnfilterED #4: Dr. Vivek Tayal

UnfilterED #4: Dr. Vivek Tayal

Dr. Vivek Tayal of Carolinas Medical Center, a pioneer of using ultrasound in the emergency department, reflects on his role in establishing ultrasound use in emergency medicine and much more! Ultra...

29 Tammi 202045min

Podcast 536:  Epistaxis 101

Podcast 536: Epistaxis 101

Contributor:  Dylan Luyten, MD Educational Pearls: Clear the nasal passages - have the patient, if stable, blow their nose to dislodge any clot that might be in the way Searching for the source of bl...

28 Tammi 20208min

Podcast 535: A Prescription for Falls

Podcast 535: A Prescription for Falls

Contributor: Aaron Lessen, MD Educational Pearls: Emergency department evaluation of falls, particularly in the elderly, should include an assessment of risk factors Common causes of falls in th...

28 Tammi 20202min

Mental Health Monthly #1: Decision Making Capacity

Mental Health Monthly #1: Decision Making Capacity

In the first episode of this new series, the complexities of decision making capacity are discussed. References and Further Reading: [1] Appelbaum, P. S. (2007). Assessment of patients' competence to...

22 Tammi 202010min

Suosittua kategoriassa Tiede

rss-mita-tulisi-tietaa
utelias-mieli
tiedekulma-podcast
rss-poliisin-mieli
rss-duodecim-lehti
docemilia
radio-antro
rss-ylistys-elaimille
filocast-filosofian-perusteet
rss-luontopodi-samuel-glassar-tutkii-luonnon-ihmeita
rss-sosiopodi
mielipaivakirja
rss-tervetuloa-tervemenoa
rss-tervetta-skeptisyytta