Podcast 529: Hemophilia
Emergency Medical Minute8 Tammi 2020

Podcast 529: Hemophilia

Contributor: Aaron Lessen, MD

Educational Pearls:

  • Hemophilia is characterized by bleeding (A /B) A is is 8, B (chrstmas, 9)
  • Hemophilia refers to a group of bleeding disorders caused by a deficiency in a certain clotting factor. The two most common are hemophilia A (caused by a lack of factor VIII), and B (caused by a lack of factor 9)
  • Most cases are inherited in an X-linked recessive manner. Therefore, males are the most commonly affected. However, spontaneous cases do occur in all sexes.
  • People with hemophilia can present to the ED with a variety of bleeding complications including hemarthrosis, intracranial hemorrhage, and GI bleeds.
  • Treatment is guided by the type of hemophilia and the degree of bleeding, with the most severe cases being treated with replacement of 100% of that person's deficient clotting factor.
  • Timely treatment improves outcomes, so consider empiric therapy in those with known hemophilia

References

Hemophilia A in the third millennium.Franchini M, Mannucci PM Blood Rev. 2013 Jul;27(4):179-84. Epub 2013 Jun 28.

Rheumatic manifestations of hematologic disorders.Aviña-Zubieta JA, Galindo-Rodriguez G, Lavalle C Curr Opin Rheumatol. 1998;10(1):86.

The molecular genetics of hemophilia: blood clotting factors VIII and IX.Lawn RM Cell. 1985;42(2):405.

Guidelines for the management of hemophilia.Srivastava A, Brewer AK, Mauser-Bunschoten EP, Key NS, Kitchen S, Llinas A, Ludlam CA, Mahlangu JN, Mulder K, Poon MC, Street A, Treatment Guidelines Working Group on Behalf of The World Federation Of Hemophilia Haemophilia. 2013 Jan;19(1):e1-47. Epub 2012 Jul 6.

Summarized by Will Dewispelaere, MS4 | Edited by Erik Verzemnieks, MD

Jaksot(1148)

CBHW Summit: Substance Use During the Perinatal Period

CBHW Summit: Substance Use During the Perinatal Period

From DU's 1st annual Colorado Behavioral Health and Wellness Summit: Contributors: Tracy Vozar, Ph.D., Director of the Infant and Early Childhood Mental Health Specialty, and Jennifer M. Tippett, Psy...

26 Marras 20191h 5min

CBHW Summit: Strategies for Remaining Adaptive and Agile in Response to the Dynamic Issue of Substance (Mis)use

CBHW Summit: Strategies for Remaining Adaptive and Agile in Response to the Dynamic Issue of Substance (Mis)use

From DU's 1st annual Colorado Behavioral Health and Wellness Summit: Contributors: Marion Rorke, MPH, Substance Use Resource Coordinator, City and County of Denver, and Maggie Kauffman, MPH, Health Eq...

26 Marras 201932min

CBHW Summit: Project Colorado Opioid Synergy

CBHW Summit: Project Colorado Opioid Synergy

From DU's 1st annual Colorado Behavioral Health and Wellness Summit: Contributors: Lesley Brooks, MD, Chief Medical Officer, Sunrise Community Health Center; Medical Director – Quality, North Colorado...

26 Marras 201919min

CBHW Summit: Innovative and Interactive Approaches to Suicide Assessment and Safety Planning

CBHW Summit: Innovative and Interactive Approaches to Suicide Assessment and Safety Planning

From DU's 1st annual Colorado Behavioral Health and Wellness Summit: Contributor: Khara Croswaite Brindle, MA, LPC, ACS, Croswaite Counseling, PLLC

26 Marras 20191h 13min

CBHW Summit: Benzos - Boon or Blunder?

CBHW Summit: Benzos - Boon or Blunder?

From DU's 1st annual Colorado Behavioral Health and Wellness Summit: Contributor: Steven Wright, MD, Colorado Consortium for Prescription Drug Abuse Prevention

26 Marras 20191h 51min

Podcast 519: Malaria Drug Resistance

Podcast 519: Malaria Drug Resistance

Contributor: John Winkler Educational Pearls: There is increasing resistance to antimalarial drugs, especially in P. falciparum. This trend started with chloroquine, but is now spreading to the other...

19 Marras 20193min

Podcast 518: Professional Complications

Podcast 518: Professional Complications

Contributor: Jared Scott, MD Educational Pearls In a 4 yr period at 2 hospital systems, unprofessional behavior of surgeons was monitored via a complaint system. Number of complaints was compared wit...

16 Marras 20193min

Podcast 517: It's all about the PEEP

Podcast 517: It's all about the PEEP

Contributor: Dylan Luyten, MD Educational Pearls: Bag-valve masks (BVM) typically  have a port to connect O2 to. Unfortunately room air becomes entrained in the mask, reducing the FiO2 delivered to t...

12 Marras 20195min

Suosittua kategoriassa Tiede

rss-mita-tulisi-tietaa
utelias-mieli
tiedekulma-podcast
rss-poliisin-mieli
rss-duodecim-lehti
docemilia
radio-antro
rss-ylistys-elaimille
filocast-filosofian-perusteet
rss-luontopodi-samuel-glassar-tutkii-luonnon-ihmeita
rss-sosiopodi
mielipaivakirja
rss-tervetuloa-tervemenoa
rss-tervetta-skeptisyytta