Podcast 668: Opioid-Induced Hyperalgesia

Podcast 668: Opioid-Induced Hyperalgesia

Contributor: Donald Stader, MD

Educational Pearls:

  • Opioids target kappa and NMDA receptors that can lead to central nervous system sensitization and therefore increased pain
  • For patients with opioid-induced hyperalgesia (OIH), oral ketamine (25-50 mg) can be used to treat their pain as it targets the NMDA receptor
  • Other treatments is IV magnesium, NSAIDs, tylenol, and clonidine
  • Buprenorphine and methadone are options for chronic pain management in the setting of OIH

References

Lee M, Silverman SM, Hansen H, Patel VB, Manchikanti L. A comprehensive review of opioid-induced hyperalgesia. Pain Physician. 2011;14(2):145-161.

Summarized by John Spartz, MS3 | Edited by Erik Verzemnieks, MD

The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at www.emergencymedicalminute.com/cme-courses/ and create an account.

Donate to EMM today!



Jaksot(1146)

Podcast #407:  Choose your own blister adventure

Podcast #407: Choose your own blister adventure

Author: Don Stader, MD Educational Pearls:   Three options for a blister in partial thickness burns:  do nothing, unroof it, or poke a hole in it Recent study suggest that aspirating the blister may ...

21 Marras 20181min

Podcast #406:  PO vs. IV Tylenol

Podcast #406: PO vs. IV Tylenol

Author: Don Stader, MD Educational Pearls: Intravenous Tylenol currently is many times more expensive than oral Single ED study comparing the two has methodology flaws and there is a lack of additi...

19 Marras 20182min

Podcast #405:  Infant Walkers

Podcast #405: Infant Walkers

Author: Don Stader, MD Educational Pearls: Recent study has revealed that infant walkers are more harmful than helpful Infant walkers can also delay motor function The American Academy of Pediatric...

16 Marras 201822s

Podcast #404: Electric Scooter Injuries

Podcast #404: Electric Scooter Injuries

Author: Sam Killian, MD Educational Pearls: Recent news articles are showing an increase in injuries related to riding electric scooters Year-to-year, scooter injuries have increased as high as thr...

14 Marras 20182min

Podcast #403:  Meniscus Lock

Podcast #403: Meniscus Lock

Author: Mark Hinton, MD Educational Pearls: Meniscus lock can occur with a tear leading to inability to extend the knee Treatment can include an intra-articular joint block followed by straightenin...

12 Marras 20183min

Podcast #402: Rapid sequence intubation medications

Podcast #402: Rapid sequence intubation medications

Educational Pearls: RSI includes induction agent (sedative) and a paralytic Succinylcholine is a depolarizing paralytic of rapid onset and short duration with contraindications in hyperkalemic states...

9 Marras 20184min

Podcast #401: Foreign Body Aspiration

Podcast #401: Foreign Body Aspiration

Author: Gretchen Hinson, MD Educational Pearls: Diagnosis can be difficult and often delayed Asymmetric breath sounds, choking, stridor may be present, but children also present asymptomatically Peak...

6 Marras 20186min

Podcast #400: ECMO

Podcast #400: ECMO

Author: Dylan Luyten, MD Educational Pearls: Extracorporeal membrane oxygenation (ECMO) is similar to bypass ECMO is being utilized routinely at some centers and even prehospital in cardiac arrest ...

2 Marras 20186min

Suosittua kategoriassa Tiede

tiedekulma-podcast
rss-mita-tulisi-tietaa
rss-poliisin-mieli
docemilia
rss-duodecim-lehti
utelias-mieli
rss-astetta-parempi-elama-podcast
rss-luontopodi-samuel-glassar-tutkii-luonnon-ihmeita
filocast-filosofian-perusteet
rss-ammamafia
rss-tiedetta-vai-tarinaa
rss-lapsuuden-rakentajat-podcast
rss-sosiopodi