Podcast 691: TXA in Head Bleeds

Podcast 691: TXA in Head Bleeds

Contributor: Ricky Dhaliwal, MD

Educational Pearls:

  • CRASH 3 Trial looked at over 12,000 patients with traumatic intracranial bleeds, randomizing patients to a therapy with TXA or standard of care without TXA
  • Dosing was 1 gram over 10 min for loading dose and then an infusion of 1 gram over 8 hours
  • Found Improvement in survival and neurologic outcomes when patient received TXA within 3 hours

References

CRASH-3 trial collaborators. Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial [published correction appears in Lancet. 2019 Nov 9;394(10210):1712]. Lancet. 2019;394(10210):1713-1723. doi:10.1016/S0140-6736(19)32233-0

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Jaksot(1145)

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Podcast 722: Lower Extremity Dislocations

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13 Loka 20211h 4min

Podcast 720: Blakemore & Minnesota Tubes: Part I

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Podcast 719: Normal Saline vs. Tap Water for Wound Irrigation

Podcast 719: Normal Saline vs. Tap Water for Wound Irrigation

Contributor: Ricky Dhaliwal, MD Educational Pearls: Multiple RCTs and a Cochrane Review found there is no difference in wound infection rates when irrigating with tap water  Pressure of the water and...

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Podcast 718: Renal Failure Follow Up

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Contributor: Aaron Lessen, MD Educational Pearls: Patients with acute renal failure often need medical management for hyperkalemia Those with severe electrolyte derangements or absent renal function ...

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Podcast 717: A cautionary tale of renal failure

Podcast 717: A cautionary tale of renal failure

Contributor: Aaron Lessen, MD Educational Pearls: Hyperkalemia can cause EKG changes such as a widened QRS The fastest electrolyte results can be obtained off a VBG with electrolytes or point-of-car...

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