Podcast 691: TXA in Head Bleeds

Podcast 691: TXA in Head Bleeds

Contributor: Ricky Dhaliwal, MD

Educational Pearls:

  • CRASH 3 Trial looked at over 12,000 patients with traumatic intracranial bleeds, randomizing patients to a therapy with TXA or standard of care without TXA
  • Dosing was 1 gram over 10 min for loading dose and then an infusion of 1 gram over 8 hours
  • Found Improvement in survival and neurologic outcomes when patient received TXA within 3 hours

References

CRASH-3 trial collaborators. Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial [published correction appears in Lancet. 2019 Nov 9;394(10210):1712]. Lancet. 2019;394(10210):1713-1723. doi:10.1016/S0140-6736(19)32233-0

The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at www.emergencymedicalminute.org/cme-courses/ and create an account.

Donate to EMM today!



Jaksot(1146)

Podcast # 465: As easy and 1, 2, 10 - Capillary Refill and Sepsis

Podcast # 465: As easy and 1, 2, 10 - Capillary Refill and Sepsis

Author: Ryan Circh, MD Educational Pearls: The 2019 ANDROMEDA-SHOCK trial compared using serum lactates to capillary refill assessment in septic shock patients to guide resuscitation Capillary refill...

5 Touko 20192min

Podcast # 464: Narcan't?

Podcast # 464: Narcan't?

Author: Aaron Lessen, MD Educational Pearls: A problem of take-home-naloxone is the administration of it by an able-bodied bystander Australian study looked at consecutive opioid overdose deaths in a...

2 Touko 20192min

Podcast # 463: Buproprion Overdose

Podcast # 463: Buproprion Overdose

Author: Erik Verzemnieks, MD Educational Pearls: Buproprion is used as an antidepressant and for smoking cessation Severe buproprion overdoses can cause seizures and lead to cardiac dysrhythmias Benz...

30 Huhti 20191min

Podcast # 462: Death after OD

Podcast # 462: Death after OD

Author: Don Stader, MD Educational Pearls: 10% of patients seen in the emergency department for opioid overdose patients will die within a year Half of these overdoses will occur in the next month Th...

27 Huhti 20192min

Podcast # 461: Breath Stacking

Podcast # 461: Breath Stacking

Author: Gretchen Hinson, MD Educational Pearls: Breath stacking occurs when a patient is unable to expire fully before another inspiration In intubated/ventilated patients, this is because adequate t...

24 Huhti 20195min

Podcast # 460: Hunting for PE in Syncope

Podcast # 460: Hunting for PE in Syncope

Author: Michael Hunt, MD Educational Pearls: Most causes of syncope are benign Pulmonary embolism can result in syncope and is life threatening A recent study of Canadian and US ED patients with s...

22 Huhti 20192min

Podcast # 459 Clonidine Ingestion

Podcast # 459 Clonidine Ingestion

Author: Julian Orenstein, MD Educational Pearls: Severe clonidine ingestion can present as a fluctuating mental status between typically accompanied by changes in vital signs (hypotension/bradycar...

20 Huhti 20193min

Podcast # 458: A Tylenol a Day Keeps the Delirium Away?

Podcast # 458: A Tylenol a Day Keeps the Delirium Away?

Author: Nick Hatch, MD Educational Pearls: A recent study investigated the effect of scheduled IV acetaminophen on the incidence of delirium in post-CABG patients in the ICU The use of scheduled IV...

17 Huhti 20193min

Suosittua kategoriassa Tiede

tiedekulma-podcast
rss-mita-tulisi-tietaa
rss-poliisin-mieli
rss-duodecim-lehti
docemilia
utelias-mieli
filocast-filosofian-perusteet
rss-ammamafia
rss-astetta-parempi-elama-podcast
rss-luontopodi-samuel-glassar-tutkii-luonnon-ihmeita
rss-sosiopodi
rss-tiedetta-vai-tarinaa