Podcast 712: Cephalosporin with a Penicillin Allergy

Podcast 712: Cephalosporin with a Penicillin Allergy

Contributor: Aaron Lessen, MD

Educational Pearls:

  • Retrospective cohort study in the Kaiser system looked at over 4 million patients receiving antibiotics to determine the effect of penicillin allergy prompts in the EHR on antibiotic prescribing
  • Half of the sites removed prompts stating penicillin allergy and half kept the prompts
  • Patients with penicillin allergies who received cephalosporins went up from 20% to 27% in areas where the prompt was remove
  • No difference in mortality or no new allergies found between the two groups
  • Reduced the use of fluoroquinolones and clindamycin in the group without the prompt

References

Macy E, McCormick TA, Adams JL, et al. Association Between Removal of a Warning Against Cephalosporin Use in Patients With Penicillin Allergy and Antibiotic Prescribing. JAMA Netw Open. 2021;4(4):e218367. Published 2021 Apr 1. doi:10.1001/jamanetworkopen.2021.8367

Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD

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Podcast 788: Tracheostomy Bleeding

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Podcast 787: TAVR and Stroke

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Podcast 786: Smiling Death

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Podcast 785: Pepper Spray

Podcast 785: Pepper Spray

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Podcast 784: Wastewater Surveillance for COVID

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Podcast 783: LAD Occlusion & Troponin

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Contributor: Jared Scott, MD Educational Pearls: A study randomized 34 healthy patient to have their left anterior descending artery (LAD) occluded by balloon for 0, 15, 30, or 90 seconds Subsequen...

23 Touko 20225min

Podcast 782: Ventilator Management

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Contributor: Aaron Lessen, MD Educational Pearls: Tidal volume is the amount of breath a patient receives in a single ventilation Traditional tidal volume (TV) setting was 10 ml/kg but studies showe...

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Podcast 781: Foxglove, Dropsy, and Salvador Dali

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