Podcast 729: Molnupiravir for COVID

Podcast 729: Molnupiravir for COVID

Contributor: Jared Scott, MD

Educational Pearls:

  • A press release from Merck introduced Molnupiravir for treatment of mild to moderate COVID-19
  • The yet to be published study is a randomized control trial at around 100 different sites
  • Reported outcomes were hospitalization and mortality from COVID and mortality from COVID
  • Molnupiravir was found to be twice as effective as placebo looking at these two endpoints (7% vs. 14%)
  • 5 day course of the drug taken twice per day costs $700, but cost-saved from using this drug was $32,000 per patient

References

https://www.merck.com/news/merck-and-ridgebacks-investigational-oral-antiviral-molnupiravir-reduced-the-risk-of-hospitalization-or-death-by-approximately-50-percent-compared-to-placebo-for-patients-with-mild-or-moderat/

https://www.merck.com/news/merck-and-ridgebacks-molnupiravir-an-oral-covid-19-antiviral-medicine-receives-first-authorization-in-the-world/

Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD

The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at https://emergencymedicalminute.org/cme-courses/ and create an account.

Donate to EMM today!

Diversity and Inclusion Award



Jaksot(1146)

Podcast # 423: Blunt Cardiac Injuries

Podcast # 423: Blunt Cardiac Injuries

Author: Mike Hunt, MD Educational Pearls: Blunt cardiac injuries most commonly occur in motor vehicle collisions, auto-pedestrian collisions, and from sports injuries The more anterior right ventri...

14 Tammi 20194min

Podcast # 422: ED Opioid Prescription Trends

Podcast # 422: ED Opioid Prescription Trends

Author: Jared Scott, MD Educational Pearls: From 1996 to 2012, the total quantity of opioids prescribed increased 647% for non-cancer pain Office based prescriptions accounted for 84% of the total ...

11 Tammi 20194min

Podcast # 421: Sweet DKA Pearls

Podcast # 421: Sweet DKA Pearls

Author: Gretchen Hinson, MD Educational Pearls:   Diabetic ketoacidosis patients are subject to electrolyte derangements Potassium should be monitored closely: K 3.3 K > 5.3 = delay potassium repl...

9 Tammi 20194min

Podcast # 420: CT Contrast and the Kidneys

Podcast # 420: CT Contrast and the Kidneys

Author: Don Stader, MD Educational Pearls: Recent meta-analysis has demonstrated that there is no significant risk for kidney injury from CT contrast Most kidney injury seen after contrast CTs wer...

7 Tammi 20192min

Podcast # 419: Etripamil

Podcast # 419: Etripamil

Author: Don Stader, MD Educational Pearls: Etripamil is an intranasal calcium channel blocker in development for use in SVT A recent study showed that etripamil has an SVT conversion rate of arou...

20 Joulu 20183min

Podcast # 418: Vertebral Artery Dissection

Podcast # 418: Vertebral Artery Dissection

Author: Don Stader, MD Educational Pearls: Vertebral artery dissection (VAD) contributes to just 2% of strokes overall but ~25% of strokes for patients VAD is associated with minor trauma (chiroprac...

17 Joulu 20183min

Podcast # 417: Water Balance

Podcast # 417: Water Balance

Author: Katie Sprinkle, MD Educational Pearls: Hyponatremia results when patients over hydrate and dilute their sodium with too much free water Symptoms of hyponatremia can mimic symptoms of dehydrat...

15 Joulu 20183min

Podcast # 416: Wide Complex Tachycardia

Podcast # 416: Wide Complex Tachycardia

Author: Aaron Lessen, MD Educational Pearls: Defined as QRS over 120 ms and rate over 120 Two major rhythms = Vetricular tachycardia (VT) or SVT with aberrancy Safest approach is to assume it is VT S...

12 Joulu 20183min

Suosittua kategoriassa Tiede

tiedekulma-podcast
rss-mita-tulisi-tietaa
rss-poliisin-mieli
docemilia
rss-duodecim-lehti
rss-luontopodi-samuel-glassar-tutkii-luonnon-ihmeita
utelias-mieli
rss-astetta-parempi-elama-podcast
filocast-filosofian-perusteet
rss-lapsuuden-rakentajat-podcast
rss-sosiopodi