Podcast 777: Grass, Weed, and Ancient Rome

Podcast 777: Grass, Weed, and Ancient Rome

Contributor: Chris Holmes, MD

Educational Pearls:

  • Antiemetics were used in ancient Rome to help with sea-sickness and included toxic substances such as wine and wormwood and white hellborn
  • The first antihistamine used for nausea, dramamine, was introduced in 1947 for motion sickness
  • After this chlorpromazine, prochlorperazine, and promethazine came about in the 1950s and 1960s
  • Cannabis, colloquially referred to as weed, isolates like THC used in the 1970s to help with chemotherapy-induced
  • After this in the 1980s, ondansetron and metoclopramide were introduced for more severe chemotherapy-induced nausea
  • Lastly, NK-1 inhibitors were introduced to treat nausea

References

Sanger GJ, Andrews PLR. A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research. Front Pharmacol. 2018;9:913. Published 2018 Sep 4. doi:10.3389/fphar.2018.00913

Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD

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Podcast 855: QT Intervals

Podcast 855: QT Intervals

​​Contributor: Travis Barlock MD Educational Pearls The QT interval represents phases 2 and 3 of ventricular plateau and repolarization, respectively. As the QT interval lengthens, more sodium an...

12 Kesä 20234min

Mental Health Monthly #16: Psychosis in the ED Part II

Mental Health Monthly #16: Psychosis in the ED Part II

Contributors: Andrew White MD & Travis Barlock MD In this follow-up episode Dr. Andrew White, a practicing psychiatrist with an addiction medicine fellowship, and Dr. Travis Barlock, an emergency phys...

7 Kesä 202324min

Episode 854: Tranq (xylazine) with Heroin

Episode 854: Tranq (xylazine) with Heroin

Contributor: Aaron Lessen, MD Educational Pearls: What is Tranq? Tranq is the street name for xylazine, a sedative drug typically used in veterinary medicine. Xylazine has recently emerged as a re...

5 Kesä 20232min

Podcast 853: Critical Care Medications - Vasopressors

Podcast 853: Critical Care Medications - Vasopressors

Contributor: Travis Barlock MD Educational Pearls: Three categories of pressors: inopressors, pure vasoconstrictors, and inodilators Inopressors:  Epinephrine - nonselective beta- and alpha-adr...

29 Touko 20235min

Podcast 852: Angioedema After Thrombolysis

Podcast 852: Angioedema After Thrombolysis

Contributor: Aaron Lessen, MD Educational Pearls: What is thrombolysis? Thrombolysis is performed by administration of a medication that promotes the body's natural ability to break up clots. These ...

22 Touko 20232min

Podcast 851: High-Dose Nitroglycerin in SCAPE

Podcast 851: High-Dose Nitroglycerin in SCAPE

Contributor: Aaron Lessen MD Educational Pearls: SCAPE (Sympathetic Crashing Acute Pulmonary Edema), formerly known as flash pulmonary edema, is a life-threatening condition due to a sudden sympathet...

15 Touko 20233min

Podcast 850: Cardiac Arrest - Entertainment vs. Reality

Podcast 850: Cardiac Arrest - Entertainment vs. Reality

Contributor: Travis Barlock, MD Educational Pearls: Sudden Cardiac Arrest (SCA) is defined as when the heart suddenly stops beating. Immediate treatment for SCA includes Cardiopulmonary Resuscitation ...

8 Touko 20232min

Mental Health Monthly #15: Psychosis in the ED: Part I

Mental Health Monthly #15: Psychosis in the ED: Part I

Contributors: Andrew White MD & Travis Barlock MD In this episode of Mental Health Monthly, Dr. Andrew White, a practicing psychiatrist with an addiction medicine fellowship, and Dr. Travis Barlock, a...

3 Touko 202331min

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