Podcast 781: Foxglove, Dropsy, and Salvador Dali

Podcast 781: Foxglove, Dropsy, and Salvador Dali

Contributor: Chris Holmes, MD

Educational Pearls:

  • Foxglove plant contains the cardiac glycoside digoxin
  • Foxglove leaf potions were once used to treat Dropsy; a historic term for symptoms of heart failure
  • Digoxin, previously used for treating heart failure, works by increases heart contraction strength and slows heart rate
  • Of note, the EKG of patient on digitalis may have a 'Dali Mustache' appearance
  • Digoxin toxicity can lead to a variety of dysrhythmias as well as neurological, GI, and metabolic effects
  • Treatment of digoxin toxicity is digoxin-immune fab, which is an antibody that binds digoxin

References

David MNV, Shetty M. Digoxin. [Updated 2021 Dec 23]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK556025/

Cummings ED, Swoboda HD. Digoxin Toxicity. [Updated 2021 Jul 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470568/?report=classic

Summarized by Kirsten Hughes, MS4 | Edited by John Spartz MS4 & Erik Verzemnieks, MD

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Podcast 658: Febrile Seizures

Podcast 658: Febrile Seizures

Contributor: Peter Bakes, MD Educational Pearls: Febrile Seizure clinical criteria 6 months - 5 years of age Rapid rise in temp No preexisting seizure disorder No other explanation for the seizure...

13 Huhti 20214min

Podcast 657: Caustic Ingestion

Podcast 657: Caustic Ingestion

Contributor: Aaron Lessen, MD Educational Pearls: Acid and alkali ingestions have differing prognosis and immediate concerns Immediate issues can include superficial irritation, severe burns, esopha...

12 Huhti 20213min

Podcast 656: Rashes

Podcast 656: Rashes

Contributor:  Peter Bakes, MD Educational Pearls: Lyme disease gives a single expanding target lesion with central clearing called erythema chronicum migrans Erythema multiforme is another targetoid ...

7 Huhti 20217min

Podcast 655: Hypothermia in Sepsis

Podcast 655: Hypothermia in Sepsis

Contributor: Adam Barkin, MD Educational Pearls: Fever is an adaptive response to infection, but elderly and immunocompromised patients may not be able to mount a hyperthermic response in sepsis Pati...

6 Huhti 20213min

Podcast 654: Depression in COVID

Podcast 654: Depression in COVID

Contributor: Aaron Lessen, MD Educational Pearls: Survey study compared depression symptom prevalence in the United States at the beginning of COVID compared to data acquired by a similar survey for...

5 Huhti 20213min

Podcast 653: Nitroglycerin Disimpaction

Podcast 653: Nitroglycerin Disimpaction

Contributor: Ricky Dhaliwal, MD, JD Educational Pearls: Glucagon administered intravenously has a high rate of adverse events (nausea/vomiting) with very weak evidence NItroglycerin too has very lim...

30 Maalis 20212min

Podcast 652: Prosthetic Hip Dislocation

Podcast 652: Prosthetic Hip Dislocation

Contributor: Jared Scott, MD Educational Pearls: While it is rare to have a native hip dislocation, it is relatively common to dislocate a prosthetic hip The mechanism for dislocation is usually add...

29 Maalis 20215min

Dr. Don Stader Shares Personal Experience of Losing his Mother to COVID-19 and Ruminates on the Culture of Death in Medicine (UnfilterED #12 Excerpt)

Dr. Don Stader Shares Personal Experience of Losing his Mother to COVID-19 and Ruminates on the Culture of Death in Medicine (UnfilterED #12 Excerpt)

A heartfelt excerpt from our most recent UnfilterED episode with Dr. Don Stader.

26 Maalis 202120min

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