Podcast 781: Foxglove, Dropsy, and Salvador Dali

Podcast 781: Foxglove, Dropsy, and Salvador Dali

Contributor: Chris Holmes, MD

Educational Pearls:

  • Foxglove plant contains the cardiac glycoside digoxin
  • Foxglove leaf potions were once used to treat Dropsy; a historic term for symptoms of heart failure
  • Digoxin, previously used for treating heart failure, works by increases heart contraction strength and slows heart rate
  • Of note, the EKG of patient on digitalis may have a 'Dali Mustache' appearance
  • Digoxin toxicity can lead to a variety of dysrhythmias as well as neurological, GI, and metabolic effects
  • Treatment of digoxin toxicity is digoxin-immune fab, which is an antibody that binds digoxin

References

David MNV, Shetty M. Digoxin. [Updated 2021 Dec 23]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK556025/

Cummings ED, Swoboda HD. Digoxin Toxicity. [Updated 2021 Jul 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470568/?report=classic

Summarized by Kirsten Hughes, MS4 | Edited by John Spartz MS4 & Erik Verzemnieks, MD

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Podcast 635: Wide Complex Tachycardias

Podcast 635: Wide Complex Tachycardias

Contributor: Peter Bakes, MD Educational Pearls: Two main differentials for wide complex tachycardia (WCT) include ventricular tachycardia (most common) and supraventricular tachycardia with aberranc...

26 Tammi 20215min

Podcast 634: D10 for Hypoglycemia

Podcast 634: D10 for Hypoglycemia

Contributor: Dylan Luyten, MD Educational Pearls: D10 may be a better alternative to D50 in correcting hypoglycemia Risks of D50: Can cause extravasation injury Risk of rebound hypoglycemia D10 ...

25 Tammi 20214min

Podcast 633: Pathologic Femur Fractures

Podcast 633: Pathologic Femur Fractures

Contributor: Jared Scott, MD Educational Pearls: Pathologic bone fractures occur due to weakened bones from chronic disease and with less force when compared to non-pathologic fractures Can be due to...

19 Tammi 20215min

Podcast 632: Neonatal Jaundice

Podcast 632: Neonatal Jaundice

Contributor: Jared Scott, MD Educational Pearls: Bilirubin is natural breakdown product of red blood cells but can be neurotoxic if levels become too high Fetal red blood cells are fragile and break ...

18 Tammi 20216min

Pharmacy Phriday #7: Bactrim Adverse Events

Pharmacy Phriday #7: Bactrim Adverse Events

Contributor: Cheyenne Bean, PharmD Educational Pearls: Bactrim (TMP-SMX) is a sulfa antibiotic used for a number of infections but can have untoward effects. Hypoglycemia can be induced by the sulfa ...

15 Tammi 20214min

Podcast 631: UK COVID-19 Mutation

Podcast 631: UK COVID-19 Mutation

Contributor: Gretchen Hinson, MD Educational Pearls: Viruses mutate frequently and a new variant of COVID has been found in the United Kingdom. Mutations typically occur due to transcription errors d...

13 Tammi 20215min

Podcast 630: Evolution of an STEMI

Podcast 630: Evolution of an STEMI

Contributor: Peter Bakes, MD Educational Pearls: Hyperacute T waves can occur immediately and typical last less than an hour Hyperacute T waves are typically broader than peaked T-waves, which are ...

12 Tammi 20215min

Podcast 629: Inferior STEMI

Podcast 629: Inferior STEMI

Contributor: Jared Scott, MD Educational Pearls: EKGs look at different angles, or vectors, of the heart's electrical conduction as it travels through the heart. Knowing how to read these vectors is ...

11 Tammi 20214min

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