Podcast 783: LAD Occlusion & Troponin

Podcast 783: LAD Occlusion & Troponin

Contributor: Jared Scott, MD

Educational Pearls:

  • A study randomized 34 healthy patient to have their left anterior descending artery (LAD) occluded by balloon for 0, 15, 30, or 90 seconds
  • Subsequently, cardiac troponins (cTns) and Copeptin were measured every 15 minutes for 3 hours, then every 30 minutes for the next 3 hours
  • 5 conclusions were drawn:
    • Copeptin is not a useful marker of cardiac ischemia
    • cTn may be detected after only 30 seconds of ischemia
    • cTn may be detected in a little as 15 minutes after ischemic event
    • After only 90 seconds of ischemia, cTn levels met threshold for MI
    • Troponin I is a better marker than troponin T as it rises faster and reaches a higher peak
  • Patients very recent or very brief ischemic events may have elevated troponin in the ED

References

Árnadóttir Á, Pedersen S, Bo Hasselbalch R, et al. Temporal Release of High-Sensitivity Cardiac Troponin T and I and Copeptin After Brief Induced Coronary Artery Balloon Occlusion in Humans [published correction appears in Circulation. 2021 Jun 22;143(25):e1116]. Circulation. 2021;143(11):1095-1104. doi:10.1161/CIRCULATIONAHA.120.046574

Summarized by Kirsten Hughes, MS4 | Edited by John Spartz, MD, MPH & Erik Verzemnieks, MD

The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at https://emergencymedicalminute.org/cme-courses/ and create an account.

Donate to EMM today!



Jaksot(1145)

Podcast 686: Vaginal Self Swabs

Podcast 686: Vaginal Self Swabs

Contributor: Jared Scott, MD Educational Pearls: Recent study evaluated vaginal self swab testing for STIs to determine if they are equally sensitive to provider-obtained swab 515 patients consented ...

29 Kesä 20213min

Podcast 685: Cultural Sensitivity with LGBTIQ+ Patients

Podcast 685: Cultural Sensitivity with LGBTIQ+ Patients

Contributor: Dr. Nick Gorton, MD Educational Pearls: Use transgender people's correct names and pronouns, the Russell study found a 56% reduction in suicide behavior with chosen name usage ⅕ to ½ of ...

28 Kesä 202110min

Podcast 684: Acidosis

Podcast 684: Acidosis

Contributor:  Nick Tsipis, MD Educational Pearls: pH 7.45=alkalemia If pH low and pCO2 high, indicates a respiratory acidosis If pH low and pCO2 low, indicates metabolic acidosis After determining ty...

23 Kesä 20216min

Podcast 683: Zofran vs. Haldol for Cannabinoid Hyperemesis Syndrome

Podcast 683: Zofran vs. Haldol for Cannabinoid Hyperemesis Syndrome

Contributor: Jared Scott, MD Educational Pearls: Around 30 patients with cannabinoid hyperemesis syndrome (CHS) randomized treatment in three arms with 8mg Zofran, Haldol 0.05 mg/kg, and Haldol 0.1 ...

22 Kesä 20215min

Podcast 682: Snake Bites

Podcast 682: Snake Bites

Contributor: Gretchen Hinson, MD Educational Pearls: Pit vipers include cottonmouths, rattlesnakes, and copperheads All have folding long fangs, triangular face, and elliptical pupils About 5,00...

21 Kesä 20216min

Podcast 681: Internal Hernias

Podcast 681: Internal Hernias

Contributor: Adam Barkin, MD Educational Pearls: Internal hernias, when bowel herniates through iatrogenic or congenital defect in mesentery, represent 1-6% of all small bowel obstructions Mortality...

16 Kesä 20215min

Podcast 680: Coronary Artery Dissection

Podcast 680: Coronary Artery Dissection

Contributor: Adam Barkin, MD Educational Pearls: Spontaneous coronary artery dissection (SCAD) is the most common cause of acute MI in women under 50 years old Risk factors include fibromuscular dys...

15 Kesä 20214min

Podcast 679: Antibiotics for CAP

Podcast 679: Antibiotics for CAP

Contributor: Peter Bakes, MD Educational Pearls: Community-acquired pneumonia (CAP) is normally stratified into outpatient-candidates vs. inpatient candidates for treatment For outpatient treatment,...

9 Kesä 20217min

Suosittua kategoriassa Tiede

tiedekulma-podcast
rss-mita-tulisi-tietaa
rss-poliisin-mieli
docemilia
rss-duodecim-lehti
rss-sosiopodi
radio-antro
filocast-filosofian-perusteet
rss-ammamafia
utelias-mieli
mielipaivakirja
rss-bios-podcast
rss-astetta-parempi-elama-podcast
rss-tiedetta-vai-tarinaa
rss-luontopodi-samuel-glassar-tutkii-luonnon-ihmeita