Dementia Researcher Blogs24 Tammi 2022

Dr Yvonne Couch - The Blood Brain Barrier

Dr Yvonne Couch, narrates her blog written for the Dementia Researcher website.

The blood-brain barrier (BBB) is the specialised system of brain microvascular endothelial cells (BMVEC) that shields the brain from toxic substances in the blood, supplies brain tissues with nutrients, and filters harmful compounds from the brain back to the bloodstream - mostly you want that barrier closed, but what about when you want therapies to pass through, because they NEED to be in the brain? Yvonne explains how the blood brain barrier works, starting with Paul Ehrlich in the late 1800s and some notes on why we should stop talking about Paul Ehrlich and the blood brain barrier - and why all of this is important in dementia and stroke.

Find the original text, and narration here on our website.

https://www.dementiaresearcher.nihr.ac.uk/guest-blog-the-blood-brain-barrier

Dr Yvonne Couch is an Alzheimer's Research UK Fellow at the University of Oxford. Yvonne studies the role of extracellular vesicles and their role in changing the function of the vasculature after stroke, aiming to discover why the prevalence of dementia after stroke is three times higher than the average. It is her passion for problem solving and love of science that drives her, in advancing our knowledge of disease. Yvonne has joined the team of staff bloggers at Dementia Researcher, and will be writing about her work and life as she takes a new road into independent research.

Enjoy listening? We're always looking for new bloggers, drop us a line. http://www.dementiaresearcher.nihr.ac.uk

This podcast is brought to you in association with Alzheimer's Research UK and Alzheimer's Society, who we thank for their ongoing support.

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