New Research Says Fasting Beats Cutting Calories – Leonie Heilbronn, Ph.D., with Dave Asprey : 781

New Research Says Fasting Beats Cutting Calories – Leonie Heilbronn, Ph.D., with Dave Asprey : 781

In this episode of Bulletproof Radio, I’m joined by Australian researcher Leonie Heilbronn, Ph.D.. Her fasting research looks at the biological pathways that support reducing the risk of chronic diseases.

Leonie leads the Obesity and Metabolism group based within the Lifelong Health Theme at South Australian Health and Medical Research Institute at Adelaide University in Adelaide, Australia. Today, I have her on to talk about her studies on fasting, many of which show more specific results than what we’ve seen in this field before. She looks at intermittent fasting, time restricted eating, calorie restriction and more.

In a particular study on women, Leoni says, “We did see that the intermittent fasting group lost a little bit more weight than the caloric restriction group, and they had better improvements in their health.” There were other positive results like reductions in diabetes and cardiovascular risk markers.

Fasting isn’t one-size-fits-all, so I asked Leonie a lot of questions about her research, such as:

  • How does the food you eat during intermittent fasting affect the fast itself?
  • What food works for some people and not others and how does that influence the effectiveness of your fast?
  • How do intermittent fasting and caloric restriction compare?
  • When should you eat your daily protein and carbs?
  • Should you consume black coffee during your fast?
  • How does time-restrictive eating affect your lifespan?


How do people respond in fasting studies? “For some people, it takes them a little while to get used to fasting and then some people just maybe never get used to it,” she says.

How do people respond in time restrictive eating studies? “I think time restrictive eating is great because you don’t really have to change everything that you’re eating and you’re still going to have some really good effects,” she says. “But I think if you started to have bad behaviors because of time pressure, then you’re not going to see the improvement that we’d hope to see.”

Leonie breaks down her research in in simple terms, so no matter what your familiarity with fasting might be, you’ll find a fascinating entry point.

Enjoy! And get more resources at https://blog.daveasprey.com/category/podcasts/

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The New Science Behind Psychedelics, Exotic Shrooms, & Daily Flow-States | Matt Zemon : 1280

The New Science Behind Psychedelics, Exotic Shrooms, & Daily Flow-States | Matt Zemon : 1280

Your brain has a gear you’ve never touched. Psychedelics can shift you into it. In this episode of The Human Upgrade, Dave Asprey uncovers how high-performance psychedelic mushrooms help you access fl...

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Why Oral Testosterone Is the Ultimate Upgrade for Energy, Mood and Longevity (Men AND Women) | Shalin Shah  : 1279

Why Oral Testosterone Is the Ultimate Upgrade for Energy, Mood and Longevity (Men AND Women) | Shalin Shah : 1279

Low testosterone is sabotaging your health, motivation, and longevity. Diet alone will not fix it. In this episode of The Human Upgrade, Dave Asprey sits down with Shalin Shah, CEO of Marius Pharmaceu...

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The Deadliest Room in Your House — And How to Detox It for Better Health | Aly Cohen MD  : 1278

The Deadliest Room in Your House — And How to Detox It for Better Health | Aly Cohen MD : 1278

Your environment is rewiring your hormones, fertility, and long-term health without your consent. In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Aly Cohen, board-certified rheuma...

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Biohacking Your Heart Health: The Life-Saving Molecule You NEED to Know | Dr. Anurag Singh : 1277

Biohacking Your Heart Health: The Life-Saving Molecule You NEED to Know | Dr. Anurag Singh : 1277

What if you could reverse the age of your heart...without leaving home? In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer of Timeline, to reveal ...

6 Touko 20251h 4min

How Laser Therapy Boosts Mood, Mental Clarity, and Consciousness with Dr. Brandon Crawford  : 1276

How Laser Therapy Boosts Mood, Mental Clarity, and Consciousness with Dr. Brandon Crawford : 1276

What if a laser could help a child speak for the first time—or reverse an “incurable” brain condition? In this episode of The Human Upgrade, Dave Asprey talks with Dr. Brandon Crawford, a leading neur...

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Conscious Bacteria? The Secret New Science of Cellular Intelligence | Zach Bush : 1275

Conscious Bacteria? The Secret New Science of Cellular Intelligence | Zach Bush : 1275

What if mitochondria weren’t just energy engines — but conscious beings guiding your survival and evolution? In this episode, Dave Asprey sits down with Zach Bush, MD, to uncover a radical new science...

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The End of Cardio? Burn Fat & Boost VO₂ Max in Just 8 Minutes a Week – with REHIT | Ulrich Dempfle  : 1275

The End of Cardio? Burn Fat & Boost VO₂ Max in Just 8 Minutes a Week – with REHIT | Ulrich Dempfle : 1275

You’ve probably heard of HIIT—but have you heard of “REHIT?” This isn’t just another workout trend...it’s a new science-backed way to train with maximum efficiency and zero wasted time. If you’re sti...

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The Real Reason You Still Feel Tired—Even When Your Bloodwork Looks Perfect | Dr Pompa : 1273

The Real Reason You Still Feel Tired—Even When Your Bloodwork Looks Perfect | Dr Pompa : 1273

Your bloodwork looks normal. Your doctor says you’re fine. But you still feel exhausted, inflamed, anxious—or worse. In this episode, Dave Asprey talks with Dr. Daniel Pompa, a leading voice in cellul...

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