Ep 156 Retinoids Part 1: How it started…

Ep 156 Retinoids Part 1: How it started…

That little bottle of retinol serum sitting on your bathroom counter - what do you know about its history? This week, we’re digging deep into the man behind the medicine, renowned dermatologist Dr. Albert Kligman, and the unethical research he conducted at Holmesburg Prison in the mid-20th century. Kligman’s research program at Holmesburg spanned decades, involved dozens of experiments (including tretinoin) and thousands of individuals, received ample funding from public universities and many pharmaceutical companies, and was generally praised until it all came crashing down in the early 1970s. But, as we’ll discover, the unethical behavior persisted even after the program’s closure as Kligman fought to get tretinoin to market. The murky history of retinoids might be a bit too long to include on the label, but this episode forces us to consider the human cost of a household product and the importance of acknowledging that history.

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Ep 9 Tuberculosis: A Slow Burn

Ep 9 Tuberculosis: A Slow Burn

Today, we’re taking a page straight out of Dickens and talking about tuberculosis- a disease as rich in history as it is in bloody sputum. We'll travel the path of an individual Mycobacterium tubercul...

2 Tammi 201859min

Ep 8 ABRACADABRA - Go Away Malaria!

Ep 8 ABRACADABRA - Go Away Malaria!

It's both a disease of dinosaurs and a plague of people. A gin and tonic might make you forget how much those bites itch, but it won't protect you much from this mosquito-borne monster. That's right p...

19 Joulu 201759min

Ep 7 Hit Me With Your Best (Polio) Shot

Ep 7 Hit Me With Your Best (Polio) Shot

A scientific rivalry for the ages, a president with a closely kept secret, and a summertime with no pool time. What do all these things have in common? Well step right up and take a listen- today we'r...

12 Joulu 20171h 1min

Ep 6 Plague Part 2: TGFA

Ep 6 Plague Part 2: TGFA

We're back with another episode all about plague-TGFA: Thank Goodness For Antibiotics! Today we'll focus on the status of plague in the modern world: where it is, where it isn't, and what we can do ab...

5 Joulu 201740min

Ep 5 Plague Part 1: The GMOAT

Ep 5 Plague Part 1: The GMOAT

That's right y'all... Today we're talking the GMOAT: The GREATEST MORTALITY OF ALL TIME: BLACK DEATH. This episode we'll cover the biology and history of one of the most epic diseases of all time- Yer...

28 Marras 201759min

Ep 4 The Poop Show

Ep 4 The Poop Show

That's right.. this is the poop show! Today we talk cholera- the bacterial disease that makes you liquid-poop your pants (and then some). Travel back in time with us to when London was a sewage-filled...

21 Marras 201749min

Ep 3 Gnarlypox

Ep 3 Gnarlypox

This week we pay tribute to one of the gnarliest diseases of all time, and the only human disease that's ever been eradicated (thus far). That's right, people- we're talking smallpox! It's gonna get g...

14 Marras 201757min

Ep 2 Skin in the Game, Horse in the Race

Ep 2 Skin in the Game, Horse in the Race

This week we tackle leprosy. That biblical (or is it?) infection that, believe it or not, is still with us today. Leprosy has an ancient history that exemplifies some of the worst of human behavior, a...

7 Marras 201754min

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