101 | David Baltimore on the Mysteries of Viruses

101 | David Baltimore on the Mysteries of Viruses

I recently saw an estimate that if you took all the novel coronaviruses in the world (the actual viruses, not patients), you could fit them into a bucket no more than a couple of liters in volume. A huge impact has been wrought by a very small amount of stuff. The world of viruses is vast and complicated, and we're still learning some of its basic features. Today's guest David Baltimore won the Nobel Prize in Physiology or Medicine for the discovery that genetic information in viruses could flow from RNA to DNA, establishing an exception to the Central Dogma of Biology. He is the author of the Baltimore Classification scheme for viruses, and has done important research in the role of viruses in diseases from AIDS to cancer. We talk about what viruses are, how they work, and the status of the novel coronavirus we are currently battling. David also has some strong opinions about public health and how we should be preparing for future outbreaks.

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David Baltimore received his Ph.D. in molecular biology from the Rockefeller Institute. He is currently the Robert Andrews Millikan Professor of Biology at Caltech. At age 37 he was awarded the Nobel Prize, which he shared with Howard Temin and Renato Dulbecco. He has served as the President of both Rockefeller University and Caltech, as well as President of the American Association for the Advancement of Science and the Founding Director of the Whitehead Institute for Biomedical Research. Among his other awards are the National Medal of Science and the Warren Alpert Foundation Prize.


Jaksot(415)

333 | Gordon Pennycook on Unthinkingness, Conspiracies, and What to Do About Them

333 | Gordon Pennycook on Unthinkingness, Conspiracies, and What to Do About Them

Why are people wrong all the time, anyway? Is it because we human beings are too good at being irrational, using our biases and motivated reasoning to convince ourselves of something that isn't quite ...

27 Loka 20251h 10min

332 | Dmitri Tymoczko on the Mathematics Behind Music

332 | Dmitri Tymoczko on the Mathematics Behind Music

Music is math that you can dance to. The fact that certain notes sound good when played together, or in succession, is related to the mathematical properties of the frequencies to which they correspon...

20 Loka 20251h 21min

AMA | October 2025

AMA | October 2025

Welcome to the October 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pat...

13 Loka 20253h 37min

331 | Solo: Fine-Tuning, God, and the Multiverse

331 | Solo: Fine-Tuning, God, and the Multiverse

Certain features of our universe seem unnatural to us. These include "constants of nature" such as the cosmological constant and the mass of the Higgs boson, as well as features of the initial conditi...

6 Loka 20251h 54min

330 | Petter Törnberg on the Dynamics of (Mis)Information

330 | Petter Törnberg on the Dynamics of (Mis)Information

A characteristic of complex systems is that individual components combine to exhibit large-scale emergent behavior even when the components were not specifically designed for any particular purpose wi...

29 Syys 20251h 12min

329 | Steven Pinker on Rationality and Common Knowledge

329 | Steven Pinker on Rationality and Common Knowledge

Getting along in society requires that we mostly adhere to certainly shared norms and customs. Often it's not enough that we all know what the rules are, but also that everyone else knows the rules, a...

22 Syys 20251h 16min

328 | Mary Roach on Replacing Parts of Our Bodies

328 | Mary Roach on Replacing Parts of Our Bodies

Like any machine, bodies occasionally break down, and it's natural to go in search of a replacement part. Ancient societies featured simple prosthetics for teeth, noses, and limbs, while modern medici...

15 Syys 20251h 7min

AMA | September 2025

AMA | September 2025

Welcome to the September 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by P...

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