6. SPECIAL EPISODE - Testosterone as a treatment for DMD with Prof Volker Straub
Decoding Duchenne1 Huhti 2019

6. SPECIAL EPISODE - Testosterone as a treatment for DMD with Prof Volker Straub

In this podcast we speak with Prof Volker Straub about Testosterone, which is sometimes given to patients with Duchenne Muscular Dystrophy (DMD) who take steroids. Steroids are part of the recognised standard of care in treating Duchenne Muscular Dystrophy (DMD). But long-term use of steroids causes a number of side effects including delayed puberty. Testosterone is sometimes given to make boys begin going through puberty. There is a clinical trial running at the John Walton Muscular Dystrophy Research Centre (JWMDRC), led by Prof Volker Straub and Dr Claire Wood, treating 15 adolescents with DMD with testosterone to induce puberty. As well as looking at the effect of testosterone on pubertal development, growth, muscle strength and function, bone mineral density and body composition, the trial is looking at the mood, quality of life and well-being of patients to assess their satisfaction with the benefits of the treatment compared to the side effects. Duchenne UK has granted £228,562.51 to pay for the extension study of this trial to look at the longer term effects of testosterone treatment following earlier treatment to induce puberty. The extension study will investigate whether testosterone treatment to induce puberty will be enough to support long term testosterone production, or whether further treatment with testosterone is needed for patients on long-term steroids to keep producing testosterone, even if puberty was successfully induced.

Jaksot(11)

11. Duchenne UK Family Funds

11. Duchenne UK Family Funds

We know that the people who are most passionate about raising money to find treatments and a cure for Duchenne Muscular Dystrophy are those who live with it every day. That's why we at Duchenne UK ...

12 Syys 20199min

10. Repurposing Drugs for DMD

10. Repurposing Drugs for DMD

Repurposing is an exciting approach to drug development; it involves looking at existing medicines, and testing them to see if they could be effective in treating Duchenne Muscular Dystrophy. Our ho...

2 Syys 201912min

9. Growing Up With DMD - Saul Catlin

9. Growing Up With DMD - Saul Catlin

Our host Clare Runacres speaks to Saul Catlin about growing up with DMD. Saul is an 18 year old man living with DMD. He is studying games design at university. If you have any questions or would lik...

31 Heinä 201914min

8. The DMD Hub - Alex Johnson, Emily Crossley, Prof Volker Straub and Emma Helsop

8. The DMD Hub - Alex Johnson, Emily Crossley, Prof Volker Straub and Emma Helsop

Our host Clare Runacres speaks about the DMD Hub with Prof Volker Straub - Professor of Medicine and Professor of Neuromuscular Genetics at Newcastle University, Emma Heslop - DMD Hub manager and Duch...

8 Heinä 201912min

7. What Is Duchenne - Dr David Bull

7. What Is Duchenne - Dr David Bull

Our host Clare Runacres speaks with Duchenne UK's Director of Research, Dr David Bull, about Duchenne muscular dystrophy. If you have any questions please email support@duchenneuk.org.

24 Kesä 201926min

5. Decoding Duchenne - Clinical trials with Dr David Bull

5. Decoding Duchenne - Clinical trials with Dr David Bull

In this episode Dr David Bull gives a breakdown about how clinical trials work. This was recorded at our Patient Information Day in September 2018. We host free patient information days twice a year. ...

7 Tammi 201917min

4. Decoding Duchenne - Advice From Parents

4. Decoding Duchenne - Advice From Parents

In this weeks episode of Duchenne UK's DECODING DUCHENNE podcast series, our host Clare Runacres interviews Lisa Kuhwald and Alex Johnson, whose son's both have Duchenne, about the time of diagnosis. ...

21 Joulu 201825min

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