#95 – A to Z on R&D: Challenges and Solutions for Sustained Antimicrobial Drug Development
Breakpoints29 Maalis 2024

#95 – A to Z on R&D: Challenges and Solutions for Sustained Antimicrobial Drug Development

In this episode, Drs. Helen Boucher (@hboucher3), Ramy Elshaboury, and Mike Dudley (@MikeMNDudley) join host, Megan Klatt (@MeganKlatt3), to discuss barriers to antimicrobial drug development, potential incentives and legislation to promote market growth, and what we can do to ensure the antimicrobial pipeline doesn’t run dry.

Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About X: @SIDPharm (https://twitter.com/SIDPharm) Instagram: @SIDPharm (https://www.instagram.com/sidpharm/) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp

References

  1. An analysis of antibacterial drug development trends in the United States, 1980-2019: Dheman N, et al. Clin Infect Dis. 2021 Dec 6;73(11):e4444-e4450. doi:10.1093/cid/ciaa859. PMID: 32584952.
  2. Antibacterial R&D at a crossroads: we’ve pushed as hard as we can…now we need to start pulling!: Rex JH, Outterson K. Clin Infect Dis. 2021 Dec 6;73(11):e4451-4453. doi:10.1093/cid/ciaa852. PMID: 32584949.
  3. No Patient Left Behind (website): https://www.nopatientleftbehind.org/ (many useful explainers of how the investment, innovation cycle, and drug pricing work)
  4. ISPOR special task force report on defining elements of value in health care – a health economics approach: Lakdawalla DN, et al. Value Health. 2018 2018 Feb;21(2):131-139. doi: 10.1016/j.jval.2017.12.007. PMID: 29477390.
  5. Generalized cost-effectiveness analysis to assess treatment value in hepatitis C: Chou JW, et al. Am J Manag Care. 2023 Dec;29(12):696-703. doi: 10.37765/ajmc.2023.89468. PMID: 38170486.

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#78 – New Therapies in HIV: The Long Road to Long-acting Antiretrovirals - Are We There Yet?

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#77 – Breakpoints Talks Breakpoints: Non-fermenters

#77 – Breakpoints Talks Breakpoints: Non-fermenters

Episode Notes Drs. Jim Lewis, Mike Satlin (@MSatlin) and Jason Pogue (@jpogue1) are back with Dr. Erin McCreary (@ErinMcCreary) for the grand finale of our five-episode miniseries all about breakpoint...

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#76 – Breakpoints Talks Breakpoints: Fluoroquinolones

#76 – Breakpoints Talks Breakpoints: Fluoroquinolones

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#75 – Breakpoints Talks Breakpoints: Aminoglycosides

#75 – Breakpoints Talks Breakpoints: Aminoglycosides

Episode Notes Drs. Jim Lewis, Mike Satlin (@MSatlin) and Jason Pogue (@jpogue1) are back with Dr. Erin McCreary (@ErinMcCreary) for episode three of a five-episode miniseries all about breakpoints! Jo...

7 Huhti 202341min

#74 – Breakpoints Talks Breakpoints: Piperacillin/tazobactam

#74 – Breakpoints Talks Breakpoints: Piperacillin/tazobactam

Episode Notes Drs. Jim Lewis, Mike Satlin (@MSatlin) and Jason Pogue (@jpogue1) are back with Dr. Erin McCreary (@ErinMcCreary) for episode two of a five-episode miniseries all about breakpoints! Join...

31 Maalis 202338min

#73 – You’re a Breakpoint, Harry: Magical Insights from CLSI and USCAST

#73 – You’re a Breakpoint, Harry: Magical Insights from CLSI and USCAST

Episode Notes Drs. Jim Lewis, Mike Satlin (@MSatlin) and Jason Pogue (@jpogue1) join Dr. Erin McCreary (@ErinMcCreary) for episode one of a five-episode miniseries all about breakpoints! Over the nex...

24 Maalis 202355min

#72 – This Isn't Just a Phage: A Discussion on Bacteriophage Therapy

#72 – This Isn't Just a Phage: A Discussion on Bacteriophage Therapy

Episode Notes Drs. Saima Aslam (@DocSaimaAslam) and Daria Van Tyne (@DariaVanTyne) join Dr. Rachel Britt (@RachelBPharmD) for a discussion on bacteriophage therapy! Tune in for a review of their role ...

17 Maalis 202359min

#71 – This is a Potential Breakup Song: Controversies in the Management of Infective Endocarditis

#71 – This is a Potential Breakup Song: Controversies in the Management of Infective Endocarditis

Episode Notes Episode Notes Inspired by lamentations on Twitter, Drs. Bobbi Jo Stoner (@BobbiJo_Stoner), Jonathan Ryder (@JonathanRyderMD) and Sami El-Dalati join Dr. Jillian Hayes (@thejillianhayes) ...

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