298 | Jeff Lichtman on the Wiring Diagram of the Brain

298 | Jeff Lichtman on the Wiring Diagram of the Brain

The number of neurons in the human brain is comparable to the number of stars in the Milky Way galaxy. Unlike the stars, however, in the case of neurons the real action is in how they are directly connected to each other: receiving signals over synapses via their dendrites, and when appropriately triggered, sending signals down the axon to other neurons (glossing over some complications). So a major step in understanding the brain is to map its wiring diagram, or connectome: the complete map of those connections. For a human brain that's an intimidatingly complex challenge, but important advances have been made on tinier brains. We talk with Jeff Lichtman, a leader in brain mapping, to gauge the current state of progress and what it implies.

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Blog post with transcript: https://www.preposterousuniverse.com/podcast/2024/12/09/298-jeff-lichtman-on-the-wiring-diagram-of-the-brain/

Jeff Lichtman received an MD/PhD from Washington University in St. Louis. He is currently the Jeremy R. Knowles Professor of Molecular and Cellular Biology and Santiago Ramón y Cajal Professor of Arts and Sciences at Harvard University. He is co-inventor of the Brainbow system for imaging neurons. He is a member of the National Academy of Sciences.

Jaksot(416)

AMA | August 2022

AMA | August 2022

Welcome to the August 2022 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patr...

1 Elo 20223h 6min

205 | John Quiggin on Interest Rates and the Information Economy

205 | John Quiggin on Interest Rates and the Information Economy

The idea of an "interest rate" might seem mundane and practical, in comparison to our usual topics around here, but there is a profound philosophical idea lurking in the background: if you lend me mon...

25 Heinä 20221h 19min

204 | John Asher Johnson on Hunting for Exoplanets

204 | John Asher Johnson on Hunting for Exoplanets

Recent years have seen a revolution in the study of exoplanets, planets that orbit stars other than the Sun (or don't orbit stars at all). After a few tentative detections in the 1990s, dedicated inst...

18 Heinä 20221h 15min

203 | N.J. Enfield on Why Language is Good for Lawyers and Not Scientists

203 | N.J. Enfield on Why Language is Good for Lawyers and Not Scientists

We describe the world using language — we can't help it. And we all know that ordinary language is an imperfect way of communicating rigorous scientific statements, but sometimes it's the best we can ...

11 Heinä 20221h 24min

AMA | July 2022

AMA | July 2022

Welcome to the July 2022 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). I take the large number of questi...

4 Heinä 20223h 26min

202 | Andrew Papachristos on the Network Theory of Gun Violence

202 | Andrew Papachristos on the Network Theory of Gun Violence

The United States is suffering from an epidemic of tragic gun violence. While a political debate rages around the topic of gun control, it remains important to understand the causes and possible remed...

27 Kesä 20221h 15min

201 | Ed Yong on How Animals Sense the World

201 | Ed Yong on How Animals Sense the World

All of us construct models of the world, and update them on the basis of evidence brought to us by our senses. Scientists try to be more rigorous about it, but we all do it. It's natural that this pro...

20 Kesä 20221h 9min

AMA | June 2022

AMA | June 2022

Welcome to the June 2022 Ask Me Anything episode of Mindscape! We are inaugurating a slightly different publication schedule, in which these monthly AMA will take the place of one of the regular Monda...

13 Kesä 20223h 4min

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