298 | Jeff Lichtman on the Wiring Diagram of the Brain

298 | Jeff Lichtman on the Wiring Diagram of the Brain

The number of neurons in the human brain is comparable to the number of stars in the Milky Way galaxy. Unlike the stars, however, in the case of neurons the real action is in how they are directly connected to each other: receiving signals over synapses via their dendrites, and when appropriately triggered, sending signals down the axon to other neurons (glossing over some complications). So a major step in understanding the brain is to map its wiring diagram, or connectome: the complete map of those connections. For a human brain that's an intimidatingly complex challenge, but important advances have been made on tinier brains. We talk with Jeff Lichtman, a leader in brain mapping, to gauge the current state of progress and what it implies.

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Blog post with transcript: https://www.preposterousuniverse.com/podcast/2024/12/09/298-jeff-lichtman-on-the-wiring-diagram-of-the-brain/

Jeff Lichtman received an MD/PhD from Washington University in St. Louis. He is currently the Jeremy R. Knowles Professor of Molecular and Cellular Biology and Santiago Ramón y Cajal Professor of Arts and Sciences at Harvard University. He is co-inventor of the Brainbow system for imaging neurons. He is a member of the National Academy of Sciences.

Jaksot(415)

128 | Joseph Henrich on the Weirdness of the West

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4 Tammi 20211h 27min

Holiday Message 2020 | The Screwy Universe

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127 | Erich Jarvis on Language, Birds, and People

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14 Joulu 20201h 15min

AMA | December 2020

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126 | David Stasavage on the Origin and History of Democracy

126 | David Stasavage on the Origin and History of Democracy

Those of us living in democracies tend to take the idea for granted. We forget what an audacious, radical idea it is to put government power into the hands of literally all of the citizens of a countr...

7 Joulu 20201h 25min

125 | David Haig on the Evolution of Meaning from Darwin to Derrida

125 | David Haig on the Evolution of Meaning from Darwin to Derrida

Aristotle conceived of the world in terms of teleological "final causes"; Darwin, or so the story goes, erased purpose and meaning from the world, replacing them with a bloodless scientific algorithm....

30 Marras 20201h 15min

124 | Solo: How Time Travel Could and Should Work

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Time! It doesn't stop, psychological effects of being under lockdown notwithstanding. How we experience time depends on our situation, but time itself just marches forward. Unless, of course, it's pos...

23 Marras 20202h 41min

AMA | November 2020

AMA | November 2020

As you have likely heard me mention before, I have an account on Patreon, where people can sign up to donate a dollar or two per episode of Mindscape. In return they get two tangible (if minor) benefi...

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