ERJ January 2018: The RESPIRE trials

ERJ January 2018: The RESPIRE trials

As part of the January issue, the European Respiratory Journal presents the latest in its series of podcasts. Deputy chief editor James Chalmers interviews the Anthony De Soyza (Newcastle University, Newcastle, UK) and Timothy Aksamit (Mayo Clinic, Rochester, MN, USA) about the RESPIRE1 and RESPIRE2 trials of ciprofloxacin in non-cystic fibrosis bronchiectasis. These two global phase III trials enrolled a total of 937 and test two dosing regimens tested (identical dose). The range of treatment estimates favours use of a ciprofloxacin dry powder inhaler (DPI), which was overall, well tolerated, with high compliance and an excellent safety profile. The ciprofloxacin DPI 14-day regimen gave a 144-day delay in the to time to first exacerbation and a 25% reduction in the frequency of exacerbations, and the 28-day regimen gave a 138-day delay in to time to first exacerbation and a 28% reduction in frequency of exacerbations.

Jaksot(79)

ERS Monograph: Sarcoidosis

ERS Monograph: Sarcoidosis

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13 Touko 202223min

ERS Monograph: Eosinophilic Lung Diseases

ERS Monograph: Eosinophilic Lung Diseases

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28 Maalis 202223min

ERS Monograph: COVID-19

ERS Monograph: COVID-19

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28 Helmi 202227min

ERS Monograph: Pulmonary Rehabilitation

ERS Monograph: Pulmonary Rehabilitation

"People's lives can be changed and [...] the important symptoms they are struggling with can be managed and in many cases, relieved" In the latest instalment of the ERS Monograph podcast series, Edit...

10 Marras 202123min

ERS Monograph: Respiratory Diseases of the Newborn Infant

ERS Monograph: Respiratory Diseases of the Newborn Infant

"In terms of preventing them coming to your clinic, the only thing we can do is focus on the early years." The lasting impact of respiratory health in the early years, pre-birth and even pre-concepti...

17 Elo 202132min

ERS Monograph: Lung Stem Cells in Development, Health and Disease

ERS Monograph: Lung Stem Cells in Development, Health and Disease

Marko Nikolic and Brigid Hogan discuss the Monograph on Lung Stem Cells in Development, Health and Disease with Editorial Board member Sheila Ramjug. Featuring a fascinating and inspiring discussion a...

14 Kesä 202135min

ERS Monograph: Supporting Tobacco Cessation

ERS Monograph: Supporting Tobacco Cessation

ERS Monograph Editorial Board member Dr Sheila Ramjug interviews Guest Editors Dr Sofia Belo Ravara, Dr Paraskevi Katsaounou and Professor Keir Lewis about the latest ERS Monograph, Supporting Tobacco...

22 Maalis 202123min

ERS Monograph: Occupational and Environmental Lung Disease

ERS Monograph: Occupational and Environmental Lung Disease

In this podcast, Dr Sheila Ramjug (member of the ERS Monograph Editorial Board) interviews Guest Editor Dr Johanna Feary and contributing author Professor Mohamed Jeebhay about the latest ERS Monograp...

4 Tammi 202126min

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